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FDA approves sNDA to include radiographic data updating label of Pfizer XELJANZ for treatment of RA

Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved a supplemental New Drug Application (sNDA) to update the current label of XELJANZ® (tofacitinib citrate) 5 mg tablets to include radiographic data from two Phase 3 studies, ORAL Scan (A3921044) and ORAL Start.

25 Feb 2014

Neuroscientists develop stimulation glove for patients suffering from stroke-related impairments

Improving the sense of touch and motor skills without active training - what sounds impossible, does actually work. Neuroscientists at the Ruhr-Universität Bochum have developed a glove that uses weak electrical pulses to stimulate the nerve fibres that connect the hands with the brain.

24 Feb 2014

New system delivers anti-inflammatory drugs to immune cells gone out of control

Researchers at the University of Illinois at Chicago have developed a system for precisely delivering anti-inflammatory drugs to immune cells gone out of control, while sparing their well-behaved counterparts. Their findings were published online Feb. 23 in Nature Nanotechnology.

24 Feb 2014

Ellex gets CE Mark approval for 2RT laser treatment of early stage AMD

Ellex Medical Lasers Limited, a pioneer in medical technologies for the diagnosis and treatment of eye disease, today announced that it has secured a CE Mark (Conformité Européenne) for its proprietary Retinal Rejuvenation Therapy (2RT) laser treatment of early Age-Related Macular Degeneration (AMD).

24 Feb 2014

State highlights: 'Health care homes' show promise in Minn.; Texas women's health providers; Fla.'s hidden costs

A selection of health policy stories from Minnesota, Texas, Louisiana, Florida, New York and Massachusetts.

24 Feb 2014

Policy statement suggests ways to improve drug safety and efficacy in children

With less than half of medications including specific labeling for children, Kathleen Neville, MD, MS, a physician at Children's Mercy Hospital, recently led an American Academy of Pediatrics (AAP) committee in updating the policy with new recommendations guiding the off-label use of drugs in pediatric patients.

24 Feb 2014

Researchers discover 'microbial Pompeii' preserved on teeth of skeletons around 1,000 years old

An international team of researchers have discovered a 'microbial Pompeii' preserved on the teeth of skeletons around 1,000 years old. The key to the discovery is the dental calculus (plaque) which preserves bacteria and microscopic particles of food on the surfaces of teeth, effectively creating a mineral tomb for microbiomes.

24 Feb 2014

Scientists discover how viral DNA of HBV can be degraded in cell nucleus

Scientists from the Helmholtz Zentrum München and the Technische Universität München have discovered how the viral DNA of the hepatitis B virus (HBV) can be degraded in the cell nucleus of liver cells, consequently allowing the virus to be eliminated.

24 Feb 2014

Prevently.com: New portal aims to help people live healthier lifestyle

Prevently.com is a new health and wellness portal that aims to help people live a healthier lifestyle. The website provides users with health information reviewed by physicians, virtual video coaching with dietitians, a personal health record that integrates with wearable fitness devices such as FitBit, social networking tools, and an ecommerce portal that allows users to purchase health products and food reviewed by physicians.

24 Feb 2014

REACT clinical trial provides valuable new insights for community gastroenterologists that benefit patients

The final results from an international clinical trial involving nearly 2,000 patients with Crohn's disease support the use of a new management strategy referred to as accelerated step-care as a best practice for the care of active Crohn's disease.

24 Feb 2014

Social/behavioral intervention strategies may help drug users avoid injection-related HCV, HIV infections

Despite a number of social/behavioral intervention and educational programs, the spread of hepatitis C (HCV) in people who inject drugs (PWIDs) remains a chronic problem.

24 Feb 2014

LJPC completes dosing in Phase 2 clinical trial of GCS-100 for treatment of chronic kidney disease

La Jolla Pharmaceutical Company (NASDAQ: LJPC) (the "Company" or "La Jolla"), a biotechnology company developing therapeutics targeting significant unmet, life-threatening diseases today announced that it has completed dosing of its Phase 2 clinical trial of GCS-100 for the treatment of chronic kidney disease ("CKD") and has collected the final data for evaluation of the primary endpoint.

23 Feb 2014

Study: Tooth decay may have detrimental effect on child's quality of life and success in life

Dental caries, commonly known as tooth decay, is the single most common chronic childhood disease. In fact, it is an infectious disease. Mothers with cavities can transmit caries-producing oral bacteria to their babies when they clean pacifiers by sticking them in their own mouths or by sharing spoons.

23 Feb 2014

Research sheds light on pathological mechanisms that trigger psoriasis lesions

Streptococcal antigens (Streptococcus pyogenes) might be directly involved in the pathological mechanisms that result in the appearance of psoriasis lesions.

21 Feb 2014

Chewable drug candidate BTI320 can potentially prevent added sugar intake

It's official: sugar is not so sweet—for our health, that is. The new study "Added Sugar Intake and Cardiovascular Diseases Mortality Among US Adults," published in JAMA Internal Medicine, examines the intake of "added sugars," and the results suggest that sugar is now an independent risk factor for heart disease and other chronic diseases.

21 Feb 2014

Ulcerative colitis patients not satisfied with current treatments according to new study

Patients with a serious type of inflammatory bowel disease, ulcerative colitis, are not satisfied with their current treatments and the majority do not have their disease under control, according to new research released today at the 9th Congress of the European Crohn’s and Colitis Organisation (ECCO) in Copenhagen. The majority (87.2 per cent) of the 250 patients with moderate to severe ulcerative colitis who were being treated with standard therapies failed to achieve control of their disease – defined either as going into remission or not having needed to use corticosteroid medications in the previous two months.1

21 Feb 2014

Genetic study reveals 11 new genetic signals are associated with blood pressure levels

A large international study analyzing genes in tens of thousands of individuals has discovered 11 new genetic signals associated with blood pressure levels. Ten of those signals are in or very near genes encoding proteins that appear to be likely targets for drugs already in existence or in development.

21 Feb 2014

Oropharyngeal cancer patients treated with CRT show decrease in voice and speech quality

Oropharyngeal cancer patients treated with combined chemotherapy and radiation therapy reported a decrease in their voice and speech quality (VSQ) for up to one year after the completion of treatment, according to research presented today at the 2014 Multidisciplinary Head and Neck Cancer Symposium.

21 Feb 2014

Highlights: Ky. malpractice bill; Texas punishes doc under abortion law; DOJ enters whistleblower case

A selection of health policy stories from Kentucky, Texas, Georgia, South Carolina, California, Colorado and Florida.

21 Feb 2014

Study determines effectiveness of gabapentin for treatment of vulvodynia in women

A chronic syndrome called vulvodynia that affects from four to seven percent of women is being studied by physicians at The Women's Health Institute at Robert Wood Johnson Medical School, part of Rutgers, The State University of New Jersey, in hopes of alleviating sometimes excruciating pain.

21 Feb 2014

Chronic News and Research

FDA approves sNDA to include radiographic data updating label of Pfizer XELJANZ for treatment of RA

Neuroscientists develop stimulation glove for patients suffering from stroke-related impairments

New system delivers anti-inflammatory drugs to immune cells gone out of control

Ellex gets CE Mark approval for 2RT laser treatment of early stage AMD

State highlights: 'Health care homes' show promise in Minn.; Texas women's health providers; Fla.'s hidden costs

Policy statement suggests ways to improve drug safety and efficacy in children

Researchers discover 'microbial Pompeii' preserved on teeth of skeletons around 1,000 years old

Scientists discover how viral DNA of HBV can be degraded in cell nucleus

Prevently.com: New portal aims to help people live healthier lifestyle

REACT clinical trial provides valuable new insights for community gastroenterologists that benefit patients

Social/behavioral intervention strategies may help drug users avoid injection-related HCV, HIV infections

LJPC completes dosing in Phase 2 clinical trial of GCS-100 for treatment of chronic kidney disease

Study: Tooth decay may have detrimental effect on child's quality of life and success in life

Research sheds light on pathological mechanisms that trigger psoriasis lesions

Chewable drug candidate BTI320 can potentially prevent added sugar intake

Ulcerative colitis patients not satisfied with current treatments according to new study

Genetic study reveals 11 new genetic signals are associated with blood pressure levels

Oropharyngeal cancer patients treated with CRT show decrease in voice and speech quality

Highlights: Ky. malpractice bill; Texas punishes doc under abortion law; DOJ enters whistleblower case

Study determines effectiveness of gabapentin for treatment of vulvodynia in women

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