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Sigma-Aldrich, Sanger Institute partner to manufacture and distribute arrayed lentiviral CRISPR library

Sigma-Aldrich Corporation today announced it has entered into an exclusive agreement with the Wellcome Trust Sanger Institute to manufacture and distribute the Sanger Institute's arrayed lentiviral CRISPR library. The library will be the first of its kind, providing researchers with a collection of individual clones designed to knock out every known human and mouse protein-coding gene using the CRISPR system.

20 Oct 2015

Sequenom enters into clinical collaboration with CU School of Medicine

Sequenom, Inc., a life sciences company committed to enabling healthier lives through the development of innovative products and services, today announced that it has entered into a clinical collaboration with the University of Colorado Denver, School of Medicine.

19 Oct 2015

UAMS researchers report positive results from treating Metastatic Merkel-cell carcinoma with idelalisib drug

Identifying a patient's genetic mutation led University of Arkansas for Medical Sciences (UAMS) physician-researcher Ling Gao, M.D., Ph.D., to an existing drug that eliminated the patient's stage IV Merkel-cell carcinoma. Gao's findings, made in collaboration with two other UAMS researchers, were published today in The New England Journal of Medicine.

19 Oct 2015

New 3D imaging technology lets researchers look at earliest signs of heart disease

Researchers have shown that people with high blood pressure develop changes in their hearts even before symptoms appear.

19 Oct 2015

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

Three teams of scientists supported by the National Institutes of Health showed that a genetic mutation linked to some forms of amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) may destroy neurons by disrupting the movement of materials in and out of the cell's nucleus, or command center where most of its DNA is stored.

19 Oct 2015

TGen researchers join international scientists in discovering how malaria protein could some day help stop cancer

Researchers at the Translational Genomics Research Institute joined an international team of scientists in discovering how a protein from malaria could some day help stop cancer.

19 Oct 2015

BWH, HSCI establish new method for making kidney structures from stem cells derived from patients

Investigators at Brigham and Women's Hospital and the Harvard Stem Cell Institute have established a highly efficient method for making kidney structures from stem cells that are derived from skin taken from patients.

19 Oct 2015

More research needed on commercially available nutrigenomics tests: Study

There is insufficient scientific evidence to support the utility of commercially available nutrigenomics tests that claim to link genetic variants to dietary intake or nutrition-related disorders.

19 Oct 2015

New research shows nicotine increases codeine-induced analgesia

According to new research in rat models, nicotine use over time increases the speed that codeine is converted into morphine within the brain, by increasing the amount of a specific enzyme. It appears smokers' brains are being primed for a bigger buzz from this common pain killer - which could put them at a higher risk for addiction, and possibly even overdose.

19 Oct 2015

NYSCF, CBR collaborate to customize creation of high-quality stem cell lines

The New York Stem Cell Foundation and Cbr Systems, Inc. DBA Cord Blood Registry today announced a collaboration to customize the creation of high-quality stem cell lines. NYSCF will create induced pluripotent stem (iPS) cell lines from umbilical cord tissue collected after birth from healthy newborns provided by CBR.

19 Oct 2015

BET protein family plays key role in regulation of normal neuronal development and function

Regulation of a family of brain proteins known as bromodomain and extra-terminal domain containing transcription regulators (BETs) plays a key role in normal cognition and behavior, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published advanced online on September 21 and in print October 19 in The Journal of Experimental Medicine.

19 Oct 2015

ToMMo constructs Japanese population reference panel from genome information of 1,070 individuals

A research group at Tohoku Medical Megabank Organization (ToMMo) has successfully constructed a Japanese population reference panel (1KJPN), from the genome information of 1,070 individuals who had participated in the cohort studies of the Tohoku Medical Megabank Project.

19 Oct 2015

New UCL study highlights genes associated with schizophrenia and obesity

Genes involved in schizophrenia and obesity have been highlighted in a new UCL study, which could lead to a better understanding of the DNA variants which affect risk of these conditions and aid the development of improved strategies for prevention and treatment.

18 Oct 2015

New research raises hope for novel cancer immunotherapy

New research by Dana-Farber Cancer Institute scientists raises the prospect of cancer therapy that works by converting a tumor's best friends in the immune system into its gravest enemies.

16 Oct 2015

Seizure control improves for TSC patients undergoing more extensive surgery

Children with the genetic disorder tuberous sclerosis complex (TSC) often need epilepsy surgery for severe, uncontrollable seizures. A new study finds that seizure control is improved for patients undergoing more extensive surgery, reports the October issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

16 Oct 2015

Brown University researchers describe new method to test HIV mutations

Tests that can distinguish whether HIV-positive people are infected with a drug-resistant strain or a non-resistant strain allow patients to get the most effective treatment as quickly as possible. In the November edition of the Journal of Molecular Diagnostics, a team of Brown University researchers describes a new method that works faster and more sensitively in lab testing than the current standard technologies.

16 Oct 2015

Genetic News and Research

Sigma-Aldrich, Sanger Institute partner to manufacture and distribute arrayed lentiviral CRISPR library

Sequenom enters into clinical collaboration with CU School of Medicine

UAMS researchers report positive results from treating Metastatic Merkel-cell carcinoma with idelalisib drug

New 3D imaging technology lets researchers look at earliest signs of heart disease

Genetic mutation linked to ALS, FTD prevents proteins from entering and exiting the cell's nucleus

TGen researchers join international scientists in discovering how malaria protein could some day help stop cancer

BWH, HSCI establish new method for making kidney structures from stem cells derived from patients

More research needed on commercially available nutrigenomics tests: Study

New research shows nicotine increases codeine-induced analgesia

NYSCF, CBR collaborate to customize creation of high-quality stem cell lines

BET protein family plays key role in regulation of normal neuronal development and function

ToMMo constructs Japanese population reference panel from genome information of 1,070 individuals

New UCL study highlights genes associated with schizophrenia and obesity

New research raises hope for novel cancer immunotherapy

Seizure control improves for TSC patients undergoing more extensive surgery

Brown University researchers describe new method to test HIV mutations

Study reveals gene mutation that increases risk of SUDEP in patients with mild forms of disease

WSU scientist wins federal grant to explore metabolism pathways, tobacco carcinogens

Analysis of high-throughput sequencing data reveals new genes linked to chronic lymphocytic leukemia

NIH's BCERP launches Columbia Mailman School & Columbia University Medical Center site

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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