Pharmaceuticals News and Research

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Why the cold hurts - research has implications for pain relief

Freeing knotted shoelaces with fingers that are frozen stiff is extremely difficult and can even be painful.

20 Jun 2007

Gene test not needed if cancer drug irinotecan given in low dose

Investigators at St. Jude Children's Research Hospital have shown that when the cancer drug irinotecan is given in low doses for multiple days, it eliminates the need to delay treatment to perform costly genetic testing that determines if the patient is at risk for serious treatment side effects, such as neutropenia.

20 Jun 2007

Scientists develop unique “switch” that can control the activity of any protein

Our bodies could not maintain their existence without thousands of proteins performing myriad vital tasks within cells. Since malfunctioning proteins can cause disease, the study of protein structure and function can lead to the development of drugs and treatments for numerous disorders.

20 Jun 2007

Dutch research project designed to reduce maternal and child mortality

Top Institute Pharma, which carries out pioneering research projects with the support of the Dutch Ministry of Health in order to develop better and safer medicines, is starting a unique research project designed to reduce maternal and child mortality.

20 Jun 2007

Orphan drug status granted to Immtech for malaria treatment pafuramidine

Immtech Pharmaceuticals, Inc. has announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation for pafuramidine (DB289) for the treatment of malaria.

19 Jun 2007

Cancer stem cells similar to normal stem cells thwart anti-cancer agents

Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual metastasis.

19 Jun 2007

New understanding of how the DNA helix replicates

A team of researchers led by University of Virginia Health System geneticists has uncovered a major secret in the mystery of how the DNA helix replicates itself time after time.

18 Jun 2007

Lupin announces FDA approval of Trandolapril tablets

Lupin Pharmaceuticals, Inc. announced that the U.S. Food and Drug Administration (FDA) has granted final approval for the Company's Abbreviated New Drug Application (ANDA) for Trandolapril Tablets, 1mg, 2mg and 4mg. Commercial shipments of Trandolapril tablets have commenced.

17 Jun 2007

Prescription and OTC pills may increase unhealthy behavior

The first FDA-approved over-the-counter weight loss pill, has hit shelves nationwide.

17 Jun 2007

Enbrel safety data for up to 8 years in patients with juvenile rheumatoid arthritis

Amgen and Wyeth Pharmaceuticals, a division of Wyeth have announced the presentation of additional data that showed that the safety profile of Enbrel, (etanercept) was maintained with long-term use in patients with moderate-to-severe juvenile rheumatoid arthritis (JRA) who completed up to eight years of therapy.

17 Jun 2007

Gaps in diabetes care identified

A symposium, sponsored by the American Journal of Nursing (AJN) in collaboration with the American Diabetes Association, the American Association of Diabetes Educators, Joslin Diabetes Center and the University of Pennsylvania School of Nursing identified barriers to, and strategies for, more effective diabetes self management and reaffirmed the nurse's critical role to facilitate better patient self care.

17 Jun 2007

Solvay Pharmaceuticals submits supplemental NDA for AndroGel

Solvay Pharmaceuticals, Inc., has announced that it submitted a supplemental New Drug Application (sNDA) for AndroGel (testosterone gel) 1% CIII to the U.S. Food and Drug Administration (FDA) for treatment in male adolescents ages 13-17 years old with primary or secondary hypogonadism.

17 Jun 2007

Changing face of dialysis care in the United States

As medical, economic, and policy trends converge to alter the way dialysis care is organized and financed, protecting the unique relationship between dialysis patients and the kidney specialists who direct their care is a top priority, according to a special feature in the July Journal of the American Society of Nephrology.

17 Jun 2007

U.S. DOJ investigation of Bristol-Myers Squibb in Plavix patent settlement resolved

Bristol-Myers Squibb has pleaded guilty to two counts of violating 18 U.S.C. Sec. 1001 in U.S. District Court for the District of Columbia. This guilty plea resolved as to the company the previously disclosed investigation by the Antitrust Division of the U.S. Department of Justice into the proposed settlement of the Plavix patent litigation with Apotex Inc., and Apotex Corp. (Apotex).

16 Jun 2007

Don't flush old or unused medications

Your spring cleaning is done. Or is it? Did you clean out your medicine cabinet? Before you flush old or unused medication, precautions need to be taken.

16 Jun 2007

Scientists extend life of fruit fly

In a triumph for pests, scientists have figured out how to make the fruit fly live longer.

16 Jun 2007

Snake venom medication

A chemist at the Vienna University of Technology (TU Vienna) is looking for unusual structures in snake venom and plans to prove their medical effectiveness.

16 Jun 2007

New model shows how simple chemical and physical processes may have laid the foundation for life

Before life emerged on earth, either a primitive kind of metabolism or an RNA-like duplicating machinery must have set the stage, so experts believe.

15 Jun 2007

Researchers find new mechanism of action of the anti-cancer drug sorafenib

Virginia Commonwealth University Massey Cancer Center researchers have uncovered a new mechanism of action of the anti-cancer drug sorafenib, which could stimulate the development of novel regimens in which it is combined with other molecularly targeted agents for patients with blood cancers and solid tumors.

15 Jun 2007

Structure of protein altered in autism revealed

As a result of mapping the structure of the protein complex implicated in autism spectrum disorders, a research team led by scientists at the University of California, San Diego (UCSD) Skaggs School of Pharmacy and Pharmaceutical Sciences has discovered how particular genetic mutations affect this complex and contribute to the developmental abnormalities found in children with autism.

15 Jun 2007