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Scientists reveal chemical process behind anti-cancer properties of spicy pepper plant

UT Southwestern Medical Center scientists have uncovered the chemical process behind anti-cancer properties of a spicy Indian pepper plant called the long pepper, whose suspected medicinal properties date back thousands of years.

4 Jan 2017

Penn State researchers create smart, targeted system to attack specific cancers types

Many groups are working to discover new, safer ways to deliver drugs that fight cancer to the tumor without damaging healthy cells.

4 Jan 2017

Ardelyx initiates two clinical trials to evaluate new treatment for hyperkalemia

Ardelyx, Inc., a clinical-stage company focused on enhancing the treatment of patients with gastrointestinal and cardiorenal diseases, today announced the initiation of a Phase 3 clinical trial and an onset-of-action clinical trial evaluating RDX7675 in patients with hyperkalemia, a potentially life-threatening condition common in patients with cardiorenal disease.

3 Jan 2017

Researchers develop first non-human primate X-SCID models using genome editing techniques

Researchers affiliated with the Kawasaki INnovation Gateway at SKYFRONT, have successfully generated the first ever non-human primate X-SCID models by using two genome editing techniques. The findings were published in Cell Stem Cell, July 2016.

3 Jan 2017

TSRI researchers develop new approach to find how environmental estrogens impact public health

Breast cancer researchers from the Florida campus of The Scripps Research Institute have developed a novel approach for identifying how chemicals in the environment—called environmental estrogens—can produce infertility, abnormal reproductive development, including “precocious puberty,” and promote breast cancer.

3 Jan 2017

Biological Psychiatry special issue highlights role of dopamine signaling in schizophrenia

Biological Psychiatry presents a special issue, "The Dopamine Hypothesis of Schizophrenia", dedicated to recent advances in understanding the role of dopamine signaling in schizophrenia.

2 Jan 2017

200th live donor kidney transplant offers promise of new life for the New Year

In late December in San Antonio, Texas, a 36-year-old mother of three from Jefferson City, Missouri, gave her best friend the most precious gift of all: a healthy kidney and the promise of a new life for the New Year.

31 Dec 2016

Using 'fire to fight fire' approach to battle against disease could increase severity, research shows

A treatment billed as a potential breakthrough in the fight against disease, including cancer, could back-fire and make the disease fitter and more damaging, new research has found.

30 Dec 2016

Researchers warn about taking psilocybin-containing ‘magic mushrooms’

In a survey of almost 2,000 people who said they had had a past negative experience when taking psilocybin-containing "magic mushrooms," Johns Hopkins researchers say that more than 10 percent believed their worst "bad trip" had put themselves or others in harm's way, and a substantial majority called their most distressing episode one of the top 10 biggest challenges of their lives.

30 Dec 2016

Diabetes can be prevented and reversed with carbohydrate restricted diet, says UAB expert

According to a new comprehensive financial analysis reported in the Journal of the American Medical Association and The Washington Post diabetes leads a list of just 20 diseases and conditions that account for more than half of all spending on healthcare in the United States.

30 Dec 2016

Massive sequencing and coevolution unveils secrets of human protein interactions

Cells operate like an incredibly well-synchronized orchestra of molecular interactions among proteins. Understanding this molecular network is essential not only to understand how an organism works but also to determine the molecular mechanisms responsible for a multitude of diseases.

30 Dec 2016

TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment--called environmental estrogens--can produce infertility, abnormal reproductive development, including "precocious puberty," and promote breast cancer.

30 Dec 2016

New molecular imaging technologies can make it easier to treat cancers, minimize side effects

New molecular imaging technologies can make it easier to diagnose, monitor, and treat cancers while potentially saving patients from undergoing therapies that are likely to be ineffective and playing a role in minimizing side effects, according to experts from the Abramson Cancer Center and the Perelman School of Medicine at the University of Pennsylvania.

30 Dec 2016

Psychiatric and behavioral conditions are important risk factors for long-term opioid use

A wide range of pre-existing psychiatric and behavioral conditions and the use of psychoactive drugs could be important risk factors leading to long-term use of opioid pain medications, reports a study in PAIN, the official publication of the International Association for the Study of Pain (IASP).

30 Dec 2016

New active pharmaceutical ingredient may help against severe forms of testicular cancer

A new active pharmaceutical ingredient may help against severe forms of testicular cancer, which only respond inadequately to other therapies.

30 Dec 2016

Two research studies on new molecules could potentially treat Alzheimer's disease

This year, results have been published of two significant research studies about molecules that could potentially treat Alzheimer's disease.

30 Dec 2016

Aromatase inhibitors show advantages over tamoxifen in early-stage breast cancer

The German Institute for Quality and Efficiency in Health Care (IQWiG) investigated whether and what advantages drugs from the drug class of aromatase inhibitors offer compared with other breast cancer treatments or with each other.

30 Dec 2016

Nexmos, Base Pair Biotechnologies create new class of DNA-aptamer based oxidation inhibitors

Base Pair Biotechnologies, Inc., The Aptamer Discovery Company, and Nexmos, Inc., the Aptamer Application R&D Company, announce the creation of a new class of DNA-aptamer based oxidation inhibitors.

30 Dec 2016

New strategy may bring us one step closer to "fountain of youth”

It's an exciting time to be an elderly mouse. Researchers believe that by removing senescent cells (cells with a persistent damage response), which naturally accumulate with age, senior rodents can regrow hair, run faster, and improve organ function.

30 Dec 2016

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated selumetinib and, in most cases, responded to it with tumor shrinkage.

29 Dec 2016

Drugs News and Research

Scientists reveal chemical process behind anti-cancer properties of spicy pepper plant

Penn State researchers create smart, targeted system to attack specific cancers types

Ardelyx initiates two clinical trials to evaluate new treatment for hyperkalemia

Researchers develop first non-human primate X-SCID models using genome editing techniques

TSRI researchers develop new approach to find how environmental estrogens impact public health

Biological Psychiatry special issue highlights role of dopamine signaling in schizophrenia

200th live donor kidney transplant offers promise of new life for the New Year

Using 'fire to fight fire' approach to battle against disease could increase severity, research shows

Researchers warn about taking psilocybin-containing ‘magic mushrooms’

Diabetes can be prevented and reversed with carbohydrate restricted diet, says UAB expert

Massive sequencing and coevolution unveils secrets of human protein interactions

TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

New molecular imaging technologies can make it easier to treat cancers, minimize side effects

Psychiatric and behavioral conditions are important risk factors for long-term opioid use

New active pharmaceutical ingredient may help against severe forms of testicular cancer

Two research studies on new molecules could potentially treat Alzheimer's disease

Aromatase inhibitors show advantages over tamoxifen in early-stage breast cancer

Nexmos, Base Pair Biotechnologies create new class of DNA-aptamer based oxidation inhibitors

New strategy may bring us one step closer to "fountain of youth”

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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