Genetic News and Research

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Father’s life experiences can affect health, development of both children and grandchildren

If you have diabetes, or cancer or even heart problems, maybe you should blame it on your dad's behaviour or environment. Or even your grandfather's.

9 Oct 2015

Research shows sex change hormonal treatment also changes brain chemistry

Hormonal treatments administered as part of the procedures for sex reassignment have well-known and well-documented effects on the secondary sexual characteristics of the adult body, shifting a recipient's physical appearance to that of the opposite sex.

9 Oct 2015

Researchers reveal new subtypes of invasive lobular carcinoma

Researchers from the UNC Lineberger Comprehensive Cancer Center and other academic centers have revealed new subtypes of invasive lobular carcinoma, the second most commonly diagnosed invasive breast cancer type. The findings could lead to personalized treatment approaches for the disease.

9 Oct 2015

Research finding could lead to new treatments for celiac disease

A team of researchers has discovered that bacteria found in the gut may contribute to the body's response to gluten, an important finding that could lead to new treatments for celiac disease.

9 Oct 2015

Brain & Behavior Research Foundation to honor nine scientists with Outstanding Achievement Prizes

The Brain & Behavior Research Foundation will honor nine scientists with its 2015 Outstanding Achievement Prizes for their work in schizophrenia, mood disorders, child and adolescent psychiatry, and cognitive neuroscience.

9 Oct 2015

Study: Women less likely than men to have good relief of chronic pain with long-term opioid use

Women, and especially younger women, are much less likely than men to have good relief of chronic, non-cancer pain with long-term opioid use, with only one in five women reporting low levels of pain and high levels of function with chronic opioid therapy in a new study published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

9 Oct 2015

NIH launches new Breast Cancer and the Environment Research Program focused on prevention

A new phase of the Breast Cancer and the Environment Research Program (BCERP), focused on prevention, is being launched at the National Institutes of Health. Grant-funded researchers will now work across scientific disciplines, involve new racially and ethnically diverse communities, and expand the study of risk factors that precede breast cancer, such as breast density.

9 Oct 2015

People with restless legs syndrome at higher risk for stroke, heart and kidney disease

Imagine trying to lie down and rest but feeling an uncontrollable urge to keep moving your legs. That, in a nutshell, is the ongoing ordeal facing people with restless legs syndrome. Considered a neurological, sleep, or movement disorder, RLS affects up to 1 in 10 people in the U.S. For those coping with a more severe form of RLS, countless sleepless nights--during which they may toss and turn constantly, or get up and pace the floor--can shatter quality of life.

9 Oct 2015

Study finds link between poor infant sleep and behavioral problems at toddler stage

A study recently published in Developmental Neuropsychology finds a definite link between poor infant sleep and compromised attention and behavior at the toddler stage. The research discovered that one-year-olds who experienced fragmented sleep were more likely to have difficulties concentrating and to exhibit behavioral problems at three and four years of age.

9 Oct 2015

FDA grants accelerated approval for Keytruda to treat patients with advanced NSCLC

The U.S. Food and Drug Administration today granted accelerated approval for Keytruda (pembrolizumab) to treat patients with advanced (metastatic) non-small cell lung cancer (NSCLC) whose disease has progressed after other treatments and with tumors that express a protein called PD-L1. Keytruda is approved for use with a companion diagnostic, the PD-L1 IHC 22C3 pharmDx test, the first test designed to detect PD-L1 expression in non-small cell lung tumors.

9 Oct 2015

Ambry Genetics presents groundbreaking TP53 gene data at ASHG; TP53 linked to breast cancer

Ambry Genetics (Ambry), a leader in clinical genetic diagnostics and genetics software solutions, has announced new data affirming the effectiveness of multi-gene panel testing (MGPT) in identifying TP53 gene mutations in people who might otherwise not have been tested. The findings, presented as a poster at the American Society of Human Genetics (ASHG) 2015 Annual Meeting in Baltimore, includes data collected from more than 25,000 individuals having TP53 testing, of which 187 were positive. The tested cohort is the largest to date from a single testing laboratory.

9 Oct 2015

FDA grants 12-year exclusivity to RUCONEST (C1 esterase inhibitor [recombinant])

Salix Pharmaceuticals and Pharming Group NV announced today that the U.S. Food and Drug Administration has granted 12 years of exclusivity to RUCONEST (C1 esterase inhibitor [recombinant]) 50 IU/kg.

8 Oct 2015

Invasive Salmonella infections revealed as major cause of child illness and deaths in Africa

Invasive Salmonella infections in sub-Saharan Africa are a major cause of child illness and deaths, a new body of research into this usually overlooked infectious disease has revealed.

8 Oct 2015

Gut microbiome can play significant role in the body's response to gluten

Investigators interested in celiac disease, a chronic gastrointestinal disorder caused by an immunologic response to the ingestion of gluten, have wondered why only 2% to 5% of genetically susceptible individuals develop the disease.

8 Oct 2015

Controlling TH-containing neurons can manipulate maternal behavior of females and aggression of males

Most female mammals give birth and care for their offspring, while the males often breed with multiple partners and play little role in parenting once the mating is over. Yet researchers have had a hard time pinpointing where, exactly, in the brain these differences between the sexes are located and how they translate into behavior. The extent of "hardwired parental behavior" is hotly disputed.

8 Oct 2015

Penn study forms basis for new treatment approaches for Sezary syndrome

Sezary syndrome (SS), an aggressive leukemia of mature T cells, is more complicated at a molecular level than ever suspected, according to investigators from the Perelman School of Medicine at the University of Pennsylvania.

8 Oct 2015

Dr. Paul Liu named 2015 Distinguished Alumnus for contributions to leukemia research

In his laboratory in the National Human Genome Research Institute in Bethesda, Md., Paul Liu, M.D., Ph.D., is working on targeted treatments for leukemia, a life-threatening blood cancer.

8 Oct 2015

UCSD researchers develop new microbiome analysis platform

The human microbiome -- the total collection of bacteria, viruses and other microorganisms living in and on your body -- has been linked to a variety of health and disease states, including obesity, allergies, asthma, and a rapidly growing list of other conditions. But as researchers try to sort out the complex relationship between microbial populations and human health and use that information to diagnose or treat disease, they are generating a deluge of microbial sequence data that first needs to be organized and analyzed.

8 Oct 2015

Scientists identify culprit genes behind the formation and progression of breast tumours

A team from the SingHealth Duke-NUS Academic Medical Centre, comprising scientists and clinicians from the National Cancer Centre Singapore, Singapore General Hospital and Duke-NUS Graduate Medical School, has uncovered the genetic landscape of a distinct breast tumour group called fibroepithelial tumours.

8 Oct 2015

Claritas Genomics announces launch of Claritas Clinical Exome, novel diagnostic test

Claritas Genomics, Inc., announced the launch of its Claritas Clinical Exome, at the Annual Meeting of the American Society of Human Genetics running 10/6 – 10/10 in Baltimore, MD. This novel diagnostic test is the first to exploit the strengths of multiple DNA sequencing platforms simultaneously to deliver confirmed results for a patient’s clinical whole exome within 4 weeks, compared to the industry standard of 12 weeks or more. Patients with rare disease typically seek a diagnosis for 8-12 years, receiving 3-5 separate tests at a high cost.

7 Oct 2015

Genetic News and Research

Father’s life experiences can affect health, development of both children and grandchildren

Research shows sex change hormonal treatment also changes brain chemistry

Researchers reveal new subtypes of invasive lobular carcinoma

Research finding could lead to new treatments for celiac disease

Brain & Behavior Research Foundation to honor nine scientists with Outstanding Achievement Prizes

Study: Women less likely than men to have good relief of chronic pain with long-term opioid use

NIH launches new Breast Cancer and the Environment Research Program focused on prevention

People with restless legs syndrome at higher risk for stroke, heart and kidney disease

Study finds link between poor infant sleep and behavioral problems at toddler stage

FDA grants accelerated approval for Keytruda to treat patients with advanced NSCLC

Ambry Genetics presents groundbreaking TP53 gene data at ASHG; TP53 linked to breast cancer

FDA grants 12-year exclusivity to RUCONEST (C1 esterase inhibitor [recombinant])

Invasive Salmonella infections revealed as major cause of child illness and deaths in Africa

Gut microbiome can play significant role in the body's response to gluten

Controlling TH-containing neurons can manipulate maternal behavior of females and aggression of males

Penn study forms basis for new treatment approaches for Sezary syndrome

Dr. Paul Liu named 2015 Distinguished Alumnus for contributions to leukemia research

UCSD researchers develop new microbiome analysis platform

Scientists identify culprit genes behind the formation and progression of breast tumours

Claritas Genomics announces launch of Claritas Clinical Exome, novel diagnostic test

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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