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LMU researchers identify new drug target for atherosclerosis

The enzyme Dicer processes RNA transcripts, cutting them into short segments that regulate the synthesis of specific proteins. An Ludwig-Maximilians-Universitaet in Munich team has shown that Dicer promotes the development of atherosclerosis, thus identifying a new drug target.

10 Feb 2016

Muscle protein titin plays vital role in Frank-Starling mechanism

Researchers at Illinois Institute of Technology and Loyola University have discovered new clues in the 100-year-old mystery of the Frank-Starling law of the heart: What makes the heart contract more strongly at longer lengths given the same level of calcium activation?

10 Feb 2016

Diet containing unsaturated fats positively impacts weight loss and heart health markers

A new study published in the Journal of the American Heart Association found that a diet containing unsaturated fats, such as those found in walnuts and olive oil, has similar weight loss effects as a lower fat, higher-carbohydrate diet.

10 Feb 2016

Simple strategies may help people stave off neurodegenerative condition

Diet, exercise, a good night's sleep -- all sound recommendations for mitigating one's risk for everything from heart disease to diabetes and, as it turns out, Alzheimer's.

9 Feb 2016

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

North American researchers have identified drugs that showed promising perspectives in treating cancers, according to a recent study published in Cancer Research.

9 Feb 2016

Study provides insights into molecular basis of Frank-Starling regulatory mechanism

In a finding that could lead to new drugs to treat heart failure, researchers have uncovered the molecular mechanism that regulates how the heart pumps blood.

9 Feb 2016

LifeWatch's wireless, patch-based vital signs monitoring system receives FDA clearance

LifeWatch AG, a leading developer and provider of medical solutions and remote diagnostic monitoring services in the digital health market, is pleased to announce that it has received FDA clearance for its continuous Vital Signs Monitoring Service.

9 Feb 2016

TBX5 gene expression could play key role in congenital heart disease

Congenital heart disease is the most common birth defect and the leading cause of all infant deaths in the United States. Mutations in the gene TBX5 have been shown to cause both rare and more prevalent forms of congenital heart disease, yet the underlying mechanisms have remained unclear.

9 Feb 2016

Robotic nephrectomy for inferior vena cava tumor thrombus shows promise in selected patients

Renal cell carcinoma can sometimes spread to the inferior vena cava (IVC), the body's largest vein, posing a threat to the heart and brain. Robotic nephrectomy for inferior vena cava tumor thrombus has favorable outcomes in selected patients compared with open surgery, which can have a high rate of complications, report surgeons in The Journal of Urology.

8 Feb 2016

Study reveals association between DNA methylation and type 2 diabetes

Researchers from the Hospital del Mar Medical Research Institute have found an epigenetic mechanism implicated in the regulation of blood sugar. The study, published in the journal Molecular Human Genetics, reveals that the methylation of the TXNIP gene is associated with diabetes mellitus type 2 and, in particular, average blood glucose levels.

8 Feb 2016

Positive data on ability of MyoKardia’s MYK-461 to prevent development of HCM published in Science

MyoKardia, Inc., a clinical stage biopharmaceutical company pioneering a precision medicine approach for the treatment of heritable cardiovascular diseases, today announced the publication of an article in the leading medical journal Science.

8 Feb 2016

Scientists develop potential treatment to prevent hypertrophic cardiomyopathy

More than 15 years ago, David Warshaw, Ph.D., and coworkers discovered the precise malfunction of a specific protein in the heart that leads to hypertrophic cardiomyopathy, a common culprit in cases of sudden death in young athletes.

7 Feb 2016

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

For twenty years, it has been understood that dystrophin is expressed in differentiated muscle fibers where it is part of a protein complex that crosses the membrane and connects the extracellular matrix to the actin network inside the cell to provide structural integrity.

5 Feb 2016

UTHealth researchers demonstrate new way to reduce preterm birth

Using nanoparticles to engineer a special drug, a team of researchers from McGovern Medical School at The University of Texas Health Science Center at Houston has demonstrated in pre-clinical trials a new way to both reduce preterm birth and avoid the risks of medication in pregnancy to unborn babies.

5 Feb 2016

Strong link found between incarceration of family members during childhood and heart attacks in men

A parent's incarceration has immediate, devastating effects on a family. Now, Virginia Tech and University of Toronto researchers say there may be a longer term risk: Men who as children experienced a family member's incarceration are approximately twice as likely to have a heart attack in later adulthood in comparison with men who were not exposed to such a childhood trauma.

5 Feb 2016

African-American patients with connective tissue diseases at risk for cardiovascular disease

A study based on medical records from more than a quarter million adult patients found that African-American patients with connective tissue diseases such as lupus or rheumatoid arthritis were twice as likely as white patients to suffer from narrowed or atherosclerotic blood vessels, which increase the risk of a heart attack, stroke or death.

5 Feb 2016

Study examines links between spending on social services and AIDS deaths in U.S.

Despite considerable advances in the prevention and treatment of HIV/AIDS over the past 30 years, HIV infection rates have remained stagnant in the United States for the past decade. A study by researchers at the Yale Global Health Leadership Institute examines links between spending on social services and public health and AIDS deaths in the United States.

4 Feb 2016

NIH researchers identify genetic mutation responsible for vibratory urticaria

Scientists at the National Institutes of Health have identified a genetic mutation responsible for a rare form of inherited hives induced by vibration, also known as vibratory urticaria. Running, hand clapping, towel drying or even taking a bumpy bus ride can cause temporary skin rashes in people with this rare disorder.

4 Feb 2016

U.S. panel endorses “three-parent” IVF technique

An expert committee have recommended that the U.S. government allows the clinical investigation of mitochondrial replacement techniques (MRT) to go ahead.

4 Feb 2016

PTC showcases Vuforia, ThingWorx and new ThingX technology during ThingEvent broadcast

The largest IOT-focused audience ever assembled joined PTC in taking ‘a fresh look at things’ during its recent ThingEvent™ broadcast, where the company showcased Vuforia, ThingWorx, and new ThingX™ technology to demonstrate how augmented reality can change the way companies create, operate and service smart, connected things.

4 Feb 2016

Heart News and Research

LMU researchers identify new drug target for atherosclerosis

Muscle protein titin plays vital role in Frank-Starling mechanism

Diet containing unsaturated fats positively impacts weight loss and heart health markers

Simple strategies may help people stave off neurodegenerative condition

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

Study provides insights into molecular basis of Frank-Starling regulatory mechanism

LifeWatch's wireless, patch-based vital signs monitoring system receives FDA clearance

TBX5 gene expression could play key role in congenital heart disease

Robotic nephrectomy for inferior vena cava tumor thrombus shows promise in selected patients

Study reveals association between DNA methylation and type 2 diabetes

Positive data on ability of MyoKardia’s MYK-461 to prevent development of HCM published in Science

Scientists develop potential treatment to prevent hypertrophic cardiomyopathy

Duchenne muscular dystrophy: direct effect on muscle stem cells? An interview with Dr Rudnicki

UTHealth researchers demonstrate new way to reduce preterm birth

Strong link found between incarceration of family members during childhood and heart attacks in men

African-American patients with connective tissue diseases at risk for cardiovascular disease

Study examines links between spending on social services and AIDS deaths in U.S.

NIH researchers identify genetic mutation responsible for vibratory urticaria

U.S. panel endorses “three-parent” IVF technique

PTC showcases Vuforia, ThingWorx and new ThingX technology during ThingEvent broadcast

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