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Cycle Pharmaceuticals receives license for IP on PARP inhibitor drugs for treating vascular disease

Cambridge Enterprise has exclusively licensed intellectual property relating to the use of PARP inhibitor drugs for treating vascular disease to CYCLE Pharmaceuticals.

23 Dec 2016

Blocking protein that initiates immune response against viral infections may help combat HIV

In findings they call counterintuitive, a team of UCLA-led researchers suggests that blocking a protein, which is crucial to initiating the immune response against viral infections, may actually help combat HIV.

23 Dec 2016

Researchers working to develop pill for inherited bleeding disorders

Motivated by the tribulations of hemophilia patients and their families, researchers funded by the National Institute of Biomedical Imaging and Bioengineering are working to develop a pill to treat this serious inherited bleeding disorder.

23 Dec 2016

Making muscles burn more fat and less glucose could cause diabetes, say researchers

Making muscles burn more fat and less glucose can increase exercise endurance, but could simultaneously cause diabetes, says a team of scientists from Baylor College of Medicine and other institutions.

22 Dec 2016

New computational tool can predict personal cancer driver genes to optimize treatment

Columbia University Medical Center researchers have created a computational tool that can rapidly predict which genes are implicated in an individual's cancer and recommend treatments.

22 Dec 2016

Gambian sleeping sickness could be eliminated in six years in DRC, research reveals

Gambian sleeping sickness - a deadly parasitic disease spread by tsetse flies - could be eliminated in six years in key regions in the Democratic Republic of Congo, according to new research by the University of Warwick.

22 Dec 2016

Researchers use mathematical models to explain how bacteria, cancer cells exploit bet-hedging

Modern medicine and treatments for bacterial infections and cancer have significantly increased life spans and improved quality-of-life. However, many drugs eventually fail because of the outgrowth and survival of treatment-resistant populations.

22 Dec 2016

Gene testing could help predict ovarian cancer patients' sensitivity to new class of drugs

Testing for a gene commonly mutated in ovarian cancers could pick out patients who will respond well to a promising new class of cancer drugs, a major new study reveals.

22 Dec 2016

TSRI scientists shed light on how antiviral drug stops influenza infections

A new study led by scientists at The Scripps Research Institute (TSRI) is the first to show exactly how the drug Arbidol stops influenza infections. The research reveals that Arbidol stops the virus from entering host cells by binding within a recessed pocket on the virus.

22 Dec 2016

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment.

22 Dec 2016

Generative AAE can be radically new way to discover drugs on demand

Scientists at the Pharmaceutical Artificial Intelligence group of Insilico Medicine, Inc, today announced the publication of a seminal paper demonstrating the application of generative adversarial autoencoders (AAEs) to generating new molecular fingerprints on demand.

22 Dec 2016

TSRI scientists identify microbial natural products as abundant sources of potent anticancer drugs

Scientists from the Florida campus of The Scripps Research Institute have developed an efficient process to rapidly discover new “enediyne natural products” from soil microbes that could be further developed into extremely potent anticancer drugs.

22 Dec 2016

New research offers valuable insight for developing more effective drugs to treat IBD

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis.

22 Dec 2016

UNC scientists develop new tool to study G-protein signaling

Scientists from the UNC School of Medicine have developed a new tool for studying a key process in cells called G-protein signaling, which plays a central role in the normal functioning of cells and can go awry to cause severe disease, including cancers.

22 Dec 2016

Heart attack risk for people with HIV nearly 50% higher than predicted

Current methods to predict the risk of heart attack and stroke vastly underestimate the risk in individuals with HIV, which is nearly double that of the general population, reports a new Northwestern Medicine study.

21 Dec 2016

New UCLA research recommends community clinics to routinely screen for misuse of drugs

The misuse of both prescription and illicit drugs is so prevalent in Tijuana and East Los Angeles that community clinics in those areas should routinely, though discreetly, screen for it, according to new UCLA research.

21 Dec 2016

Leaf-shaped prototype reactor could act as 'mini-factory' for drugs

To produce drugs sustainably and cheaply, anywhere you want. Whether in the middle of the jungle or even on Mars. A 'mini-factory' whereby sunlight can be captured to make chemical products.

21 Dec 2016

RAGE regulates key signaling pathway that promotes acute and chronic inflammation

Researchers have shown that Receptor for Advanced Glycation End Products helps to regulate a key signaling pathway known to promote both acute and chronic inflammation.

21 Dec 2016

Person's ‘brain speed’ may matter more than other risk factors for geriatric falls

"Why does a 30-year-old hit their foot against the curb in the parking lot and take a half step and recover, whereas a 71-year-old falls and an 82-year-old falls awkwardly and fractures their hip?" asks James Richardson, M.D., professor of physical medicine and rehabilitation at the University of Michigan Comprehensive Musculoskeletal Center.

21 Dec 2016

Dual treatment strategies lengthen lives of mice with skin cancer

By combining two treatment strategies, both aimed at boosting the immune system's killer T cells, Johns Hopkins researchers report they lengthened the lives of mice with skin cancer more than by using either strategy on its own.

21 Dec 2016

Drugs News and Research

Cycle Pharmaceuticals receives license for IP on PARP inhibitor drugs for treating vascular disease

Blocking protein that initiates immune response against viral infections may help combat HIV

Researchers working to develop pill for inherited bleeding disorders

Making muscles burn more fat and less glucose could cause diabetes, say researchers

New computational tool can predict personal cancer driver genes to optimize treatment

Gambian sleeping sickness could be eliminated in six years in DRC, research reveals

Researchers use mathematical models to explain how bacteria, cancer cells exploit bet-hedging

Gene testing could help predict ovarian cancer patients' sensitivity to new class of drugs

TSRI scientists shed light on how antiviral drug stops influenza infections

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

Generative AAE can be radically new way to discover drugs on demand

TSRI scientists identify microbial natural products as abundant sources of potent anticancer drugs

New research offers valuable insight for developing more effective drugs to treat IBD

UNC scientists develop new tool to study G-protein signaling

Heart attack risk for people with HIV nearly 50% higher than predicted

New UCLA research recommends community clinics to routinely screen for misuse of drugs

Leaf-shaped prototype reactor could act as 'mini-factory' for drugs

RAGE regulates key signaling pathway that promotes acute and chronic inflammation

Person's ‘brain speed’ may matter more than other risk factors for geriatric falls

Dual treatment strategies lengthen lives of mice with skin cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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