Pharmaceuticals News and Research

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Hydrogel to tackle H5N1

Influenza virus H5N1, which caused the recent outbreak of avian flu, may have a new enemy.

9 May 2007

Sigma-Aldrich acquires Molecular Medicine BioServices

Sigma-Aldrich Corporation has announced that it has acquired Molecular Medicine BioServices Inc. (MMB), a biopharmaceutical contract manufacturing organization (CMO) located in Carlsbad, California, to further enhance the biologics capabilities within its SAFC Pharma business segment.

9 May 2007

Study finds collective bargaining rights for independent pharmacists could cost Medicare and commercial payors $29.6 billion over five years

A key legislative priority championed by the independent drugstore lobby, HR 971, that would provide pharmacists with new, sweeping collective bargaining rights could increase prescription drug costs for Medicare and commercial payors by 11.8 percent, or $29.6 billion, over five years, according to a new analysis from CRA International released by the Pharmaceutical Care Management Association (PCMA).

9 May 2007

Medicis Pharmaceutical to resolve false claims allegations

Medicis Pharmaceutical Corporation of Scottsdale, Ariz., will pay the United States $9.8 million to settle allegations that the company violated the False Claims Act with respect to claims submitted to Medicaid, the Justice Department announced.

9 May 2007

Abbott seeks U.S. and E.U. approvals for Humira as a treatment for juvenile rheumatoid arthritis

Abbott has announced it has simultaneously submitted a supplemental Biologics License Application (sBLA) with the U.S. Food and Drug Administration (FDA) and a Type II Variation to the European Medicines Agency (EMEA) seeking approval to market HUMIRA (adalimumab) as a treatment for juvenile rheumatoid arthritis (JRA) in the U.S. and juvenile idiopathic arthritis (JIA) in the European Union (EU).

9 May 2007

Loss of a single gene in kidney cancer cells causes them to stop making mitochondria

Studying a rare inherited syndrome, researchers at Johns Hopkins have found that cancer cells can reprogram themselves to turn down their own energy-making machinery and use less oxygen, and that these changes might help cancer cells survive and spread.

8 May 2007

Scientists delete enzyme in mice so they can eat any type of fat and not get heart disease

A new study in mice raises a tantalizing possibility, that humans may one day be able to eat any kind of fat they want without raising their risk of heart disease.

8 May 2007

FDA says beware of glycerin imported from China

The Food and Drug Administration (FDA) in the United States has issued a warning to drug manufacturers, suppliers and health professionals that counterfeit drug additives have been using diethyline glycol, or DEG as a substitute for glycerin in cough medicine, fever medication and injectable drugs.

7 May 2007

Doctors say too many Brits addicted to OTC drugs

Doctors in Britain are warning about the dangers of becoming addicted to over-the-counter (OTC) medicines; they say more research is needed on how many misuse OTC drugs.

7 May 2007

Study looks at effect of methylphenidate on young ADHD drivers

When a song on the radio or the cell phone on the car seat next to a young driver beckon, she may not resist the temptation to turn up the dial or take a call while maneuvering in traffic.

4 May 2007

Steroidal hormones for contraception in women with sickle cell disease

Hormonal contraceptives are unlikely to predispose women to type 2 diabetes and appear to be safe for those with sickle cell anemia.

4 May 2007

Study shows effectiveness of Peramivir in mouse model of H5N1 virus infection

BioCryst Pharmaceuticals has announced that investigators at St. Jude Children's Research Hospital, Memphis, TN, reported favorable results evaluating peramivir treatment in an animal model of influenza using a highly virulent strain of H5N1 virus (an avian influenza strain that had caused fatal human infection in Viet Nam).

4 May 2007

$Treatment with zoledronic acid effective in reducing fractures in women with postmenopausal osteoporosis$

Treatment with zoledronic acid effective in reducing fractures in women with postmenopausal osteoporosis

A treatment for osteoporosis delivered once a year is as effective as current monthly or weekly osteoporosis regimens at reducing the incidence of bone fractures, according to a new study led by a UCSF research team.

4 May 2007

LigoCyte Pharmaceuticals presents data showing that immunization with their influenza H1N1-VLP formulation resulted in 100% protection from H1N1 and H3N2

LigoCyte Pharmaceuticals has presented preclinical data showing that immunization with their influenza virus-like particles (VLPs) induced heterosubtypic protection in a virus challenge study.

4 May 2007

Scientists discover molecular mechanism that keeps HSV-1 activation restricted to a single gene for months or even years

By adulthood, most people have suffered at least one bout of painful cold sores brought on by the Herpes simplex virus 1, also known as HSV-1.

4 May 2007

BioMarin starts phase 2a study of 6R-BH4 in sickle cell disease

BioMarin Pharmaceutical has announced that the first patient has initiated treatment in the Phase 2a clinical study of 6R-BH4 (sapropterin dihydrochloride) for the treatment of sickle cell disease (SCD).

4 May 2007

AIDS Healthcare Foundation praises Thailand for drug stance

AIDS Healthcare Foundation (AHF) has lauded the Government of Thailand for its vow to continue with plans to issue compulsory licenses for the manufacturing and importing of generic versions of lifesaving drugs, including AIDS drugs, despite the fact that the office of United States Trade Representative (USTR), elevated Thailand to its 'Priority Watch' List.

4 May 2007

U.S. trade rep places Thailand on priority watch list in annual report

The Office of the U.S. Trade Representative in its annual report released on Monday placed Thailand on its Priority Watch List in part because the country recently issued compulsory licenses for several medicines, including two antiretroviral drugs, CongressDaily reports.

2 May 2007

Senate begins debate on prescription drug user fee act reauthorization bill

The Senate on Monday began debate on a bill (S 1082) that would reauthorize the Prescription Drug User Fee Act, which will expire on Sept. 30, with senators expected to propose a number of amendments to the legislation, the AP/Dallas Morning News reports ( AP/Dallas Morning News , 4/30).

2 May 2007

Peramivir shows promise for H5N1 protection

The antiviral drug peramivir might offer humans significant protection during a pandemic of the avian influenza virus H5N1, according to results of mouse studies conducted by investigators at St. Jude Children's Research Hospital.

2 May 2007