Protein C News and Research

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Immune system plays key role in development of atherosclerosis

The immune system plays an important role in the development of atherosclerosis, the underlying cause of cardiovascular diseases. Thomas van der Heijden has discovered that immunosuppressants may play a preventative role. PhD defense 19 December.

19 Dec 2017

Zinc present in semen determines male fertility, study shows

Trace levels of zinc present in semen is a vital determinant of male fertility, a recent study in Bangladesh capital Dhaka concludes.

19 Dec 2017

Treatment for skin cancer could be more effective if combined with arthritis drug

Treatment for the most deadly form of skin cancer could be more effective if combined with a well-known drug for rheumatoid arthritis, new research has shown.

19 Dec 2017

TSRI scientists uncover new insights into regulatory network behind axon termination

All things must come to an end. This is particularly true for neurons, especially the extensions called axons that transmit electrochemical signals to other nerve cells. Without controlled termination of individual neuron growth, the efficient and accurate construction of a nervous system is in serious jeopardy.

19 Dec 2017

Study shows vital role for maternally inherited gene in embryonic development

A new study indicates an essential role for a maternally inherited gene in embryonic development. The study found that zebrafish that failed to inherit specific genetic instructions from mom developed fatal defects earlier in development, even if the fish could make their own version of the gene.

18 Dec 2017

Researchers identify novel mechanism that protects from brain tumor

A group of researchers at the Spanish National Cancer Research Centre have identified a protein called RanBP6 as a new regulator of EGFR. In a paper published in Nature Communications they show how silencing of RanBP6 promoted glioma growth, by upregulating EGFR expression.

18 Dec 2017

Moderate exercise reduces progression of Marfan syndrome symptoms in mice

Regular physical activity is a common therapy for people with cardiovascular problems, but not recommended to those with Marfan syndrome, a rare disease of the connective tissue, but mainly affecting the cardiovascular system.

18 Dec 2017

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Understanding how cancer cells are able to metastasize -- migrate from the primary tumor to distant sites in the body -- and developing therapies to inhibit this process are the focus of many laboratories around the country.

18 Dec 2017

Excessive copper in diabetes impedes ability to make new blood vessels

It's a metal we worry thieves will steal from our air conditioners or power lines, but inside our bodies too much copper can result in a much larger loss.

18 Dec 2017

Gene that could be associated with reduced pain response found

Researchers found an Italian family, the Marsilis that have six individuals who respond significantly differently to pain than others. This includes a 78-year-old lady and her two daughters and their three children.

18 Dec 2017

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

A new study from The Wistar Institute revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells that expose the antigens on their surface to activate the T cells.

15 Dec 2017

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

CANCER RESEARCH Danish researchers have just presented a previously unknown mechanism that inhibits the ability of cells to develop into cancer cells. Their findings have important implications for the understanding of how cancer starts, and how to improve the treatment of illness in the future.

15 Dec 2017

‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins

When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins when they are most toxic, detailing them down to the atomic level.

15 Dec 2017

Researchers examine human mutations' impact on therapeutic effect of medicine

Every person has a unique DNA sequence in their genome. Now researchers from the University of Copenhagen and the MRC Laboratory of Molecular Biology in Cambridge have tried to quantify what these differences in the genome mean in the context of the genes targeted by drugs.

15 Dec 2017

Researchers explore how toxic protein clusters linked to Parkinson's disrupt brain cells

Researchers have glimpsed how the toxic protein clusters that are associated with Parkinson's Disease disrupt the membranes of healthy brain cells, creating defects in the cell walls and eventually causing a series of events that induce neuronal death.

15 Dec 2017

Extracellular vesicles can be used to effectively delay progression of kidney damage

Researchers have demonstrated for the first time that extracellular vesicles - tiny protein-filled structures - isolated from amniotic fluid stem cells (AFSCs) can be used to effectively slow the progression of kidney damage in mice with a type of chronic kidney disease.

15 Dec 2017

Rare gene mutation gives rise to low sensitivity to pain

Researchers at University College London have identified a rare gene mutation in an Italian family who have little sensitivity to some forms of pain. Chronic pain caused by conditions such as lower back pain and osteoarthritis is one of the most prominent causes of disability worldwide, as assessed by the Global Burden of Disease reviews.

15 Dec 2017

Protein C News and Research

Immune system plays key role in development of atherosclerosis

Zinc present in semen determines male fertility, study shows

Treatment for skin cancer could be more effective if combined with arthritis drug

TSRI scientists uncover new insights into regulatory network behind axon termination

Study shows vital role for maternally inherited gene in embryonic development

Researchers identify novel mechanism that protects from brain tumor

Moderate exercise reduces progression of Marfan syndrome symptoms in mice

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Excessive copper in diabetes impedes ability to make new blood vessels

Gene that could be associated with reduced pain response found

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

‘Sushi-like’ nanodiscs provide structural snapshots of misfolding proteins

Researchers examine human mutations' impact on therapeutic effect of medicine

Researchers explore how toxic protein clusters linked to Parkinson's disrupt brain cells

Extracellular vesicles can be used to effectively delay progression of kidney damage

Rare gene mutation gives rise to low sensitivity to pain

Study provides insights into molecular mechanisms regulating cellular fate of SCCs

Muscle paralysis may promote breakdown of bones

New high precision machine-learning model could help accelerate drug discovery

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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