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β-blockers could regenerate infant heart muscle, mitigate effects of congenital heart disease

Surgery can mend congenital heart defects shortly after birth, but those babies will carry a higher risk of heart failure throughout the rest of their lives. Yet, according to a Science Translational Medicine study published today by UPMC Children's Hospital of Pittsburgh researchers, β-blockers could supplement surgery to regenerate infant heart muscle and mitigate the lasting effects of congenital heart disease.

9 Oct 2019

New algorithm hand-picks which cancer mutations are promising targets for immunotherapy

As tumor cells multiply, they often spawn tens of thousands of genetic mutations. Figuring out which ones are the most promising to target with immunotherapy is like finding a few needles in a haystack.

9 Oct 2019

Using tape strips to obtain skin biomarkers in children with atopic dermatitis

Applying strips of adhesive tape to skin lesions and non-lesional skin is a non-invasive way to obtain biomarkers to track the severity of early-onset pediatric eczema or atopic dermatitis in infants and young children, researchers report for the first time.

9 Oct 2019

Addressing social needs in health care delivery can help achieve better health outcomes

Addressing social needs as a part of health care delivery can help achieve better health outcomes and potentially address major challenges in the United States health care system, according to a recently published consensus report by the National Academies of Sciences, Engineering and Medicine.

9 Oct 2019

Novel cancer-driving mutation discovered in vast non-coding regions of the cancer genome

An Ontario-led research group has discovered a novel cancer-driving mutation in the vast non-coding regions of the human cancer genome, also known as the "dark matter" of human cancer DNA.

9 Oct 2019

New blood test could help hasten the diagnosis of brain tumors

A blood test which could help to accelerate the diagnosis of brain cancer has been developed in research led at the University of Strathclyde.

9 Oct 2019

Unique immune cell linked to remission in patients with triple negative breast cancer

A unique type of immune cell has been discovered in human breast tissue, and breast cancer patients with more of these cells are more likely to survive, finds new research from the Francis Crick Institute and King's College London.

From The Francis Crick Institute 9 Oct 2019

Survey: Very few Americans are concerned about the health effects of bad posture

The average American adult spends more than three and a half hours looking down at their smartphones every day.

9 Oct 2019

Vaccine for deadly RSV could be on the way, scientists say

A vaccine for the common and sometimes deadly RSV (respiratory syncytial virus) has been elusive, but scientists say a new discovery puts them much closer to success.

9 Oct 2019

They enrolled in medical school to practice rural medicine. What happened?

The University of Kansas School of Medicine-Salina opened in 2011 — a one-building campus in the heart of wheat country dedicated to producing the rural doctors the country needs.

9 Oct 2019

Study explores steroid prescribing rates for patients with inflammatory bowel disease

Steroid therapy is commonly used to treat acute attacks of the inflammatory bowel diseases ulcerative colitis and Crohn's disease; however, because it does not provide long-term benefits and it carries a risk of serious side effects, it should not be used to treat inflammatory bowel disease for more than three months.

9 Oct 2019

Paclitaxel-coated devices used for widening blocked arteries not linked to increased mortality

Devices coated with a drug called paclitaxel that are used for widening blocked arteries in legs and feet are safe and not linked to an increase in deaths, according to a study of nearly 65,000 patients, published in the European Heart Journal today (Wednesday).

9 Oct 2019

McLean Hospital receives grant through NIH HEAL Initiative to address national opioid crisis

As part of its efforts to reverse the opioid crisis that continues to grip the nation, the National Institutes of Health has named McLean Hospital as a recipient of a grant through the Helping to End Addiction Long-term Initiative (NIH HEAL Initiative).

9 Oct 2019

Dog owners live longer

Taking care of pets has been shown to provide a plethora of health benefits. Now, dog lovers may have a new reason to love their pets more as two new studies found that owning a dog is tied to a longer life, with a lower risk of premature death, especially among those who had a heart attack and stroke.

9 Oct 2019

IU research examines trends in public perceptions of violence in people with mental illness

In response to recent mass shootings and consistent public outcry, President Donald Trump's administration is considering a controversial proposal to monitor people with mental illness in hopes of preventing mass shootings.

8 Oct 2019

Suicide risk remains high in people with low intelligence in their youth

People with low scores on intelligence tests in adolescence run a higher risk of suicide and suicide attempt later in life.

8 Oct 2019

Study may lead the way to decrease DLBCL relapse, development of second primary cancer

With improved treatments, especially the use of anti-cancer immunotherapies, more than two-thirds of all patients diagnosed with diffuse large B-cell lymphoma (DLBCL) will survive. However, after treatment, patients are at a small but real risk of developing a new cancer, called a second primary cancer.

8 Oct 2019

MedSafer helps reduce inappropriate medications prescribed to older people

The elderly are often prescribed multiple medications for different health conditions. While some medications are needed, polypharmacy and medication overload can be costly and even harmful. However, reducing the number of potentially inappropriate medications that seniors take on a daily basis is an ongoing challenge.

8 Oct 2019

Peripherally inserted central catheters associated with serious allergic reactions in patients

Peripherally inserted central catheters (PICCs) that use a magnetized tip to guide insertion were associated with serious allergic reactions in patients, according to a study published today in Infection Control & Hospital Epidemiology, the journal for the Society for Healthcare Epidemiology of America. Severe adverse reactions occurred in patients within minutes of PICC insertion.

8 Oct 2019

Differences at the single-cell level can predict responses to BRAF inhibitor therapy

Patients with advanced melanoma have been able to live longer because of several newly approved targeted treatment options, including BRAF and MEK inhibitors. However, patients will often have different responses to the same treatment due to genetic variability.

8 Oct 2019

Hospital News and Research

β-blockers could regenerate infant heart muscle, mitigate effects of congenital heart disease

New algorithm hand-picks which cancer mutations are promising targets for immunotherapy

Using tape strips to obtain skin biomarkers in children with atopic dermatitis

Addressing social needs in health care delivery can help achieve better health outcomes

Novel cancer-driving mutation discovered in vast non-coding regions of the cancer genome

New blood test could help hasten the diagnosis of brain tumors

Unique immune cell linked to remission in patients with triple negative breast cancer

Survey: Very few Americans are concerned about the health effects of bad posture

Vaccine for deadly RSV could be on the way, scientists say

They enrolled in medical school to practice rural medicine. What happened?

Study explores steroid prescribing rates for patients with inflammatory bowel disease

Paclitaxel-coated devices used for widening blocked arteries not linked to increased mortality

McLean Hospital receives grant through NIH HEAL Initiative to address national opioid crisis

Dog owners live longer

IU research examines trends in public perceptions of violence in people with mental illness

Suicide risk remains high in people with low intelligence in their youth

Study may lead the way to decrease DLBCL relapse, development of second primary cancer

MedSafer helps reduce inappropriate medications prescribed to older people

Peripherally inserted central catheters associated with serious allergic reactions in patients

Differences at the single-cell level can predict responses to BRAF inhibitor therapy

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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