Bleeding News and Research

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'Novel' analysis addresses antiplatelet benefits in real-world CHD patients

Researchers demonstrate a means of gauging the effects of drugs tested in randomised trials in real-world patients.

28 Jun 2016

CYP2C19 gene variants undermine clopidogrel stroke prevention

The first look at CYP2C19 mutations in the context of a randomised controlled trial has confirmed suspicions that they affect the efficacy of clopidogrel in patients with acute stroke.

24 Jun 2016

Investigators evaluate history of gingival inflammation during first, second trimester of pregnancy

Today at the 94th General Session & Exhibition of the International Association for Dental Research, researcher Michael Reddy, University of Alabama at Birmingham, USA, will present a study titled "Gingivitis During the First/Second Trimesters of Pregnancy."

24 Jun 2016

Overweight and obesity increase risk for periodontitis

Today at the 94th General Session & Exhibition of the International Association for Dental Research, researcher Marco Peres, The University of Adelaide, South Australia, will present a study titled "Overweight and Obesity Impact on Periodontitis: A Brazilian Birth Cohort."

24 Jun 2016

NOACs match warfarin for atrial fibrillation

Real-world study data from Denmark show that non-vitamin K antagonist oral anticoagulants are effective alternatives to warfarin in patients with non-valvular atrial fibrillation in a routine care setting.

23 Jun 2016

Pipeline Embolization Device safe, effective for treatment of complex brain aneurysms

A recently introduced technology called the Pipeline Embolization Device (PED) can provide a less-invasive approach for difficult-to-treat aneurysms of the arteries supplying blood to the front of the brain, reports a study in the July issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

22 Jun 2016

New Aspirin-Guide mobile app helps clinicians and patients make informed decisions about aspirin use

Low dose aspirin is recommended by clinicians as a preventive measure for patients who have already had a heart attack or stroke, but the risk of taking low-dose aspirin to prevent or delay a first heart attack or stroke is less clear, as the benefit for reducing the risk of cardiovascular disease (CVD) must be balanced with the increased risk of gastrointestinal or other bleeding.

21 Jun 2016

AF patients at risk for stroke mostly treated with aspirin-only prescription instead of blood thinners

Researchers at University of California San Diego School of Medicine and University of California, San Francisco School of Medicine report that more than 1 in 3 atrial fibrillation (AF) patients at intermediate to high risk for stroke are treated with aspirin alone, despite previous data showing this therapy to be inferior to blood thinners.

21 Jun 2016

Apixaban effective in polypharmacy setting

The superiority of apixaban over warfarin in patients with atrial fibrillation is maintained in those taking multiple medications, shows further analysis of the ARISTOTLE trial.

21 Jun 2016

Brain imaging finds link between blood-brain barrier disruption and severity of bleeding after stroke therapy

In a study of stroke patients, investigators confirmed through MRI brain scans that there was an association between the extent of disruption to the brain's protective blood-brain barrier and the severity of bleeding following invasive stroke therapy. The results of the National Institutes of Health-funded study were published in Neurology.

20 Jun 2016

Worsening renal function linked to increased cardiovascular risk in AF

Patients with atrial fibrillation and declining renal function are at increased risk of subsequent stroke or systemic embolism, major bleeding and death, US researchers report.

17 Jun 2016

Watchman device for irregular heart rhythms may be preferable to standard blood thinning medications

A new study by a Yale researcher may support the use of a device for patients suffering from irregular heart rhythms.

17 Jun 2016

Resolution to train public, professional responders in bleeding control techniques receives overwhelming support

Yesterday the American Medical Association's House of Delegates approved a resolution introduced by the American College of Surgeons and other medical societies to train more professional first responders (i.e., police and firefighters) and civilians as immediate responders in the essential techniques of bleeding control and to place bleeding control kits (containing tourniquets, pressure bandages, hemostatic dressings, and gloves) with first responders.

16 Jun 2016

Simple blood test could help diagnose endometriosis

Endometriosis is a chronic, often painful disease affecting up to 10 percent of women of reproductive age in the U.S. How it develops is not well understood, and detecting it with certainty requires surgery.

16 Jun 2016

'Nonserious' side effects may lead to antiplatelet discontinuation

Most adverse events that lead patients to discontinue antiplatelet drugs are not rated as serious by clinical trial criteria, shows analysis of the PEGASUS-TIMI 54 trial.

16 Jun 2016

FDA approves novel stomach-draining device to treat obesity

The U.S. Food and Drug Administration today approved a new obesity treatment device that uses a surgically-placed tube to drain a portion of the stomach contents after every meal.

15 Jun 2016

Portal vein hypertension diminishes after hepatitis C recovery

This inflammatory viral infection of the liver causes inflexible scar tissue to form. This in turn impedes blood flow through the organ, with resulting hypertension in the portal vein.

15 Jun 2016

Study provides more insight into treatment options for severe hemophilia A

Families of children with severe hemophilia A may want to take a fresh look at treatment options from human plasma. A study published in the New England Journal of Medicine on May 26 showed that participants who received a recombinant therapy— the present standard in the United States — developed antibodies or "inhibitors" to the treatments at almost twice the rate as those whose treatments were made from human plasma.

14 Jun 2016

Age no barrier to vorapaxar use in ACS

The protease-activated receptor 1 inhibitor vorapaxar offers the same benefits to older and younger patients with non-ST segment elevation acute coronary syndromes, shows further analysis of the TRACER trial.

14 Jun 2016