Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Combining NELL-1 with BMP2 therapy may promote bone development

Bone morphogenetic protein-2 (BMP2) is used clinically to promote bone repair. However, the high BMP2 concentrations required to stimulate bone growth in humans may produce life-threatening adverse effects such as cervical swelling in spinal fusion procedures, a problem that prompted an FDA warning in 2008.

7 Jan 2016

New TAU study offers tangible hope of curing Mantle Cell Lymphoma

With a median survival rate of just five to seven years, Mantle Cell Lymphoma (MCL) is considered the most aggressive known blood cancer -- and available therapies are scarce. Three thousand Americans are diagnosed with MCL every year, and despite progress in personalized therapies to treat metastases elsewhere in the body, systemic therapeutic drug delivery to cancerous blood cells continues to challenge the world of cancer research.

6 Jan 2016

Argon Medical Devices completes acquisition of three vascular products from Rex Medical

Argon Medical Devices, Inc. announced the completed acquisition of three vascular products from Rex Medical, LLC. The OptionELITE Retrievable Vena Cava Filter, CLEANER Rotational Thrombectomy System, and UltraStream Chronic Hemodialysis Catheter are now wholly owned by Argon Medical Devices, Inc.

5 Jan 2016

Bayer to present new research findings on Xofigo (radium Ra 223 dichloride) injection at ASCO GU 2016

Bayer announced today that new research findings on Xofigo (radium Ra 223 dichloride) injection will be presented at the 2016 Genitourinary Cancers Symposium of the American Society of Clinical Oncology (ASCO GU) taking place January 7 – 9 in San Francisco.

4 Jan 2016

Rich Pharmaceuticals obtains FDA approval to begin Phase 1/2 study in AML and MDS patients

Rich Pharmaceuticals, Inc. is pleased to announce that the Company has received approval from the U.S. Food and Drug Administration to commence its Phase 1/2 clinical for the treatment of Acute Myelocytic Leukemia (AML) and Myelodysplastic Syndrome (MDS) patients.

28 Dec 2015

SCCA's Fred Hutch Bone Marrow Transplant Program recognized for outstanding survival rates

The Fred Hutch Bone Marrow Transplant Program at Seattle Cancer Care Alliance has earned recognition by the Center for International Blood and Marrow Transplant Research for outperforming its expected one-year survival rates for allogeneic transplant patients - those who receive donated adult blood-forming stem cells.

23 Dec 2015

Researchers identify cause of rare syndrome consistent with Fanconi Anemia

An international team of researchers has established the cause of rare syndrome consistent with Fanconi Anemia: a de novo mutation in a so called RAD51 gene, which is responsible for repairing damages in the DNA.

23 Dec 2015

Women suffering from blood clots can safely take hormone replacement therapy with anticoagulants

New research published online today in Blood, the Journal of the American Society of Hematology (ASH), is the first to demonstrate that women on blood thinners can take estrogen-containing contraception or hormone replacement therapy without an increased risk of blood clots or uterine bleeding.

23 Dec 2015

Stem cell therapy not significantly better than conventional treatment for Crohn's disease

A clinical trial to test the effectiveness of a stem cell therapy among adults with difficult to treat Crohn's disease has found it is not significantly better than conventional treatment in producing sustained disease remission after one year.

18 Dec 2015

CRCHUM researchers find mechanism responsible for rejection of organ transplants

A new cellular structure responsible for previously unexplained rejection of organ transplants has been identified by researchers at the University of Montreal Hospital Research Centre.

17 Dec 2015

Study offers new view of how cancer cells transform normal cells through 'metastatic hijacking'

Metastasis - or the spread of cancer from one part of the body to other parts - accounts for more than 90 percent of cancer-related deaths. Although the cells that seed metastasis and the sites that they tend to travel to have been increasingly studied over the years, little has been known about how cancer migrates from a primary site, such as breast tissue, to a secondary site, such as the brain or bone marrow.

16 Dec 2015

Molecular signatures can predict flu vaccine responses in young and old

What factors inhibit strong responses to seasonal flu vaccines in the elderly? Why do anti-flu antibodies last longer after vaccination in some people? Answers are emerging from an Emory University-based systems biology analysis of blood samples from more than 400 volunteers who received seasonal flu vaccines. Bali Pulendran, PhD, led a team of researchers who tracked patterns of gene expression, known as molecular signatures, of strong immune responses in volunteers' blood across five consecutive seasons from 2007 to 2011.

16 Dec 2015

Researchers discover first broad spectrum drug that can potently kill aging cells in culture

Researchers from the University of Arkansas for Medical Sciences and other institutions are reporting the discovery of the first broad spectrum drug that can potently kill senescent (or aging) cells in culture and effectively clear the cells in animals by specifically targeting a pathway that is critical for the survival of senescent cells.

15 Dec 2015

Researchers discover new way for early detection of potentially deadly fungal infection in leukemia patients

A team of researchers have discovered a new way for early detection of a potentially deadly fungal infection in patients with suppressed immune systems such as those being treated for leukemia or have had an organ transplant.

15 Dec 2015

$Combination of adult stem cells and parathyroid hormone may speed healing process for bone fractures$

Combination of adult stem cells and parathyroid hormone may speed healing process for bone fractures

A combination of adult stem cells and parathyroid hormone significantly increased new bone formation in laboratory animals and may speed the healing process for human bone fractures caused by osteoporosis, a new study shows.

9 Dec 2015

Researchers find new significant link between NPM protein and development of AML

A team of researchers from the National University of Singapore has found a new significant correlation between the protein nucleophosmin (NPM) and the development of an aggressive form of blood cancer called acute myeloid leukemia (AML).

8 Dec 2015

Web-based survey system for symptom collection benefits cancer patients

Systematic collection of cancer patients' symptoms using computer surveys was linked to less frequent emergency room admissions, longer average chemotherapy adherence, greater quality of life improvements, and improved survival, according to a new randomized, controlled trial spearheaded by a UNC Lineberger Comprehensive Cancer Center researcher.

8 Dec 2015

Plasmacytoid dendritic cells may not contribute to late-stage lupus

For years, biomedical researchers have suspected that a specific set of immune cells are responsible for causing disease in lupus patients, but until now they haven't known for sure one way or the other.

8 Dec 2015

Macrophages play key role in maintaining healthy arteries after inflammation

Researchers from the University of Toronto have found that a specific cell type plays a key role in maintaining healthy arteries after inflammation. It's a discovery that could provide treatment options for cardiovascular disease -- one of the leading causes of death in Canada.

8 Dec 2015

Pediatric chemotherapy regimen improves outcomes in young adults with ALL

Using a pediatric chemotherapy regimen to treat young adults with acute lymphoblastic leukemia (ALL) significantly improved their outcomes compared to what has historically been achieved with 'adult' treatment protocols, report Dana-Farber Cancer Institute scientists.

8 Dec 2015

Bone Marrow News and Research

Further Reading

Combining NELL-1 with BMP2 therapy may promote bone development

New TAU study offers tangible hope of curing Mantle Cell Lymphoma

Argon Medical Devices completes acquisition of three vascular products from Rex Medical

Bayer to present new research findings on Xofigo (radium Ra 223 dichloride) injection at ASCO GU 2016

Rich Pharmaceuticals obtains FDA approval to begin Phase 1/2 study in AML and MDS patients

SCCA's Fred Hutch Bone Marrow Transplant Program recognized for outstanding survival rates

Researchers identify cause of rare syndrome consistent with Fanconi Anemia

Women suffering from blood clots can safely take hormone replacement therapy with anticoagulants

Stem cell therapy not significantly better than conventional treatment for Crohn's disease

CRCHUM researchers find mechanism responsible for rejection of organ transplants

Study offers new view of how cancer cells transform normal cells through 'metastatic hijacking'

Molecular signatures can predict flu vaccine responses in young and old

Researchers discover first broad spectrum drug that can potently kill aging cells in culture

Researchers discover new way for early detection of potentially deadly fungal infection in leukemia patients

Combination of adult stem cells and parathyroid hormone may speed healing process for bone fractures

Researchers find new significant link between NPM protein and development of AML

Web-based survey system for symptom collection benefits cancer patients

Plasmacytoid dendritic cells may not contribute to late-stage lupus

Macrophages play key role in maintaining healthy arteries after inflammation

Pediatric chemotherapy regimen improves outcomes in young adults with ALL

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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