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Findings link antihistamine use to adverse pregnancy outcomes

Women with a severe form of morning sickness who take antihistamines to help them sleep through their debilitating nausea are significantly more likely to experience adverse pregnancy outcomes, including low birth weight babies and premature births, a UCLA study has found.

11 Jun 2013

Brain circuits involved in compulsive behavior reveal a surprising connection with obesity

What started as an experiment to probe brain circuits involved in compulsive behavior has revealed a surprising connection with obesity.

11 Jun 2013

Viewpoints: Selling Obamacare in Arizona; 'Hassle-free' marketplace; Seeking the 'grand bargain'

You may not admit it, but you are a fan of Obamacare and Gov. Jan Brewer knows it. The Republicans who run the Arizona legislature don't like Obamacare. And the Republicans who control the U.S. House of Representatives don't like it. But you do. You may deny it. You may not even know it. But you do. And that will help the governor get her Medicaid expansion plan through the legislature (EJ Montini, 6/6).

11 Jun 2013

Stephen J. Lippard to receive 2014 Priestley Medal from American Chemical Society

Stephen J. Lippard, Ph.D., Arthur Amos Noyes Professor of Chemistry at the Massachusetts Institute of Technology and associate editor of the Journal of the American Chemical Society, will receive the 2014 Priestley Medal from the American Chemical Society.

11 Jun 2013

2013 World Stem Cell Report to be published as special supplement to journal Stem Cells and Development

The Genetics Policy Institute and Mary Ann Liebert, Inc., publishers have announced that the 2013 World Stem Cell Report will be published as a special supplement to the peer-reviewed journal Stem Cells and Development. Dr. Graham Parker and Bernard Siegel will serve as Co-Editors-in-Chief, joined by Rosario Isasi (McGill University) as Managing Editor.

11 Jun 2013

Cytosine methylation plays key role in development of childhood ALL

Changes in an epigenetic mechanism that turns expression of genes on and off may be as important as genetic alterations in causing pediatric acute lymphoblastic leukemia, according to a study led by scientists at St. Jude Children's Research Hospital and published in the June 10 online edition of the Journal of Clinical Investigation.

11 Jun 2013

Researchers receive grant from Arthritis Research UK to study genes associated with hip osteoarthritis

Medical research charity Arthritis Research UK has awarded £250,000 to a team of researchers at the University of Bristol and the University of Aberdeen to study which genes can lead to people developing painful and common osteoarthritis of the hip.

11 Jun 2013

Researchers find master regulator of EMT and metastasis

The predominant cause of death in cancer patients is metastasis, the formation of secondary tumors in other organs like the brain, liver, and lungs. Cancer cells detach from the original primary tumor and reach a single cell or group of cells in another organ. The cells of the body normally remain in place through adhering to an extracellular substance. However, cancer cells learn how to release themselves from these bonds and invade surrounding tissues, blood, and the lymphatic system.

11 Jun 2013

Bone tumor identified in the rib of 120,000-year-old Neandertal

The first-known definitive case of a benign bone tumor has been discovered in the rib of a young Neandertal who lived about 120,000 years ago in what is now present-day Croatia.

10 Jun 2013

Brain-training computer games may help restore memory and competency to forensic psychiatry patients

Brain-training computer games may help restore memory and competency to forensic psychiatry patients in state mental hospitals, researchers say.

10 Jun 2013

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

By applying light stimulation to highly specific neurons in the brain, the researchers managed to re-establish normal behaviour in mice that had beforehand presented pathological repetitive behaviour similar to that observed in human patients suffering from obsessive-compulsive disorders.

10 Jun 2013

Genetic testing for cancer-causing mutations in affected families is very low, study finds

A new study of the use of genetic testing for cancer-causing mutations in affected families in France has found that its take-up is very low.

10 Jun 2013

Data emphasise need for comprehensive analysis of mtDNA in mitochondrial disease patients

French scientists have discovered that supposedly rare mutations in the mitochondria, the 'power plants' of human cells responsible for creating energy, account for more than 7% of patients with a mitochondrial disease manifesting itself as a respiratory deficiency.

10 Jun 2013

Scientists discover how Arc protein helps translate learning into memory

Scientists at the Gladstone Institutes have deciphered how a protein called Arc regulates the activity of neurons-providing much-needed clues into the brain's ability to form long-lasting memories. These findings, reported today in Nature Neuroscience, also offer newfound understanding as to what goes on at the molecular level when this process becomes disrupted.

10 Jun 2013

USC scientists unlock mystery of why new cases of Noonan Syndrome are so common

Scientists at USC have unlocked the mystery of why new cases of the genetic disease Noonan Syndrome are so common: a mutation that causes the disease disproportionately increases a normal father's production of sperm carrying the disease trait.

10 Jun 2013

Researchers discover potential target for cancer-fighting drugs

As tumors grow, their centers are squeezed of oxygen. And so tumors must flip specific genetic switches to survive in these hypoxic environments.

10 Jun 2013

Study: Non-invasive blood test could reshape standards in prenatal testing

New research has found that routine screening using a non-invasive test that analyzes fetal DNA in a pregnant woman's blood can accurately detect Down's syndrome and other genetic fetal abnormalities in the first trimester. Published early online in Ultrasound in Obstetrics & Gynecology, the results suggest that the test is superior to currently available screening strategies and could reshape standards in prenatal testing.

10 Jun 2013

Researchers find new way to repair genetic defects in the skin cells of epidermolysis bullosa patients

A research team led by pediatric blood and marrow transplantation experts Mark Osborn, Ph.D. and Jakub Tolar, M.D., Ph.D. from the Masonic Cancer Center, University of Minnesota, have discovered a remarkable new way to repair genetic defects in the skin cells of patients with the skin disease epidermolysis bullosa.

10 Jun 2013

Researchers find way to differentiate iPSCs into mature human neurons in the brain

Difficult-to-study diseases such as Alzheimer's, schizophrenia, and autism now can be probed more safely and effectively thanks to an innovative new method for obtaining mature brain cells called neurons from reprogrammed skin cells. According to Gong Chen, the Verne M. Willaman Chair in Life Sciences and professor of biology at Penn State University and the leader of the research team, "the most exciting part of this research is that it offers the promise of direct disease modeling, allowing for the creation, in a Petri dish, of mature human neurons that behave a lot like neurons that grow naturally in the human brain."

10 Jun 2013

Discovery of impaired molecular pathway may help treat children with leukemia

Through genetic engineering of laboratory models, researchers at Dartmouth-Hitchcock Norris Cotton Cancer Center have uncovered a vulnerability in the way cancer cells diverge from normal regenerating cells that may help treat children with leukemia as reported in the journal PNAS on June 3, 2013.

7 Jun 2013

Genetic News and Research

Findings link antihistamine use to adverse pregnancy outcomes

Brain circuits involved in compulsive behavior reveal a surprising connection with obesity

Viewpoints: Selling Obamacare in Arizona; 'Hassle-free' marketplace; Seeking the 'grand bargain'

Stephen J. Lippard to receive 2014 Priestley Medal from American Chemical Society

2013 World Stem Cell Report to be published as special supplement to journal Stem Cells and Development

Cytosine methylation plays key role in development of childhood ALL

Researchers receive grant from Arthritis Research UK to study genes associated with hip osteoarthritis

Researchers find master regulator of EMT and metastasis

Bone tumor identified in the rib of 120,000-year-old Neandertal

Brain-training computer games may help restore memory and competency to forensic psychiatry patients

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

Genetic testing for cancer-causing mutations in affected families is very low, study finds

Data emphasise need for comprehensive analysis of mtDNA in mitochondrial disease patients

Scientists discover how Arc protein helps translate learning into memory

USC scientists unlock mystery of why new cases of Noonan Syndrome are so common

Researchers discover potential target for cancer-fighting drugs

Study: Non-invasive blood test could reshape standards in prenatal testing

Researchers find new way to repair genetic defects in the skin cells of epidermolysis bullosa patients

Researchers find way to differentiate iPSCs into mature human neurons in the brain

Discovery of impaired molecular pathway may help treat children with leukemia

Sequencing & Genomics: Elevating Science and Healthcare eBook

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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