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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

In a piece of research conducted in collaboration, the NanoBioCel group of the UPV/EHU's Faculty of Pharmacy, and the University of Elche have designed some niosomes, which are lipid vesicles for use in gene therapies designed to treat diseases of the central nervous system.

4 Dec 2018

Researchers develop new technique to accurately isolate phloem cells across plants

Crops worldwide are increasingly vulnerable to pandemics, as diseases hitch rides on global flows of people and goods, hopping from continent to continent. Phloem diseases such as citrus greening are one particularly devastating group of plant diseases that have been wreaking economic havoc globally.

4 Dec 2018

Early gut bacterial colonization may reduce risk of developing eczema

Strains of a bacterium commonly found in skin infections may help to protect against eczema, according to new research in the British Journal of Dermatology.

4 Dec 2018

Clearer diagnosis of polio-like illness in young children

Johns Hopkins researchers have analyzed patient data from 45 cases of what they thought was acute flaccid myelitis, the polio-like outbreak occurring in U.S. children, and realized that only 75 percent of diagnosed cases were AFM.

4 Dec 2018

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

So-called CAR-T cell therapy is a promising option for treating around a fifth of patients with diffuse large B-cell lymphoma.

4 Dec 2018

New study shows that sambaqui societies were not ordinary hunter-gatherers

Shell middens are archeological features consisting mainly of the remains of marine animals thrown away near settlements over hundreds or thousands of years. They are the debris of human activity. In Brazil, they are known by the Tupi word sambaqui.

4 Dec 2018

International study increases group of lung cancer patients who may benefit from immunotherapy

The strategy for triggering the patient's own immune system to attack cancer, immunotherapy, is proving effective for more and more tumor types, although to varying degrees.

4 Dec 2018

Aerobic exercise may reduce risk of diabetes-related renal disease

Aerobic exercise may reduce the risk of diabetes-related kidney disease in some people, according to a new study. The findings are published ahead of print in the American Journal of Physiology--Renal Physiology and was chosen as an APS select article for December.

4 Dec 2018

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

University of North Carolina Lineberger Comprehensive Cancer Center researchers reported promising early results from a clinical study of an investigational cellular immunotherapy that used a patient's own, genetically engineered immune cells to recognize and fight Hodgkin and non-Hodgkin lymphoma cells.

4 Dec 2018

New strategies may improve performance of CAR-T cell therapy in treating cancer

Mayo Clinic researchers have developed two new strategies that may improve the performance of chimeric antigen receptor therapy in treating cancer. They are presenting results of their preclinical research at the 2018 annual meeting of the American Society of Hematology in San Diego.

3 Dec 2018

New drug combination could kill melanoma cells more effectively, study shows

A class of cancer drugs called protein kinase inhibitors is one of the most effective treatments for melanoma. However, in many cases, tumors eventually become resistant to the drugs and cause a relapse in the patient.

3 Dec 2018

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

A gene mutation that is believed to have safeguarded some people in 14th century Europe from the bubonic plague today may be protecting HIV patients co-infected with hepatitis C from potentially fatal liver scarring, says a University of Cincinnati College of Medicine physician-scientist.

3 Dec 2018

Using nanocarrier-delivered microRNA to target sepsis

One in three patients who die in the U.S. dies of sepsis, according to the Centers for Disease Control and Prevention. It is one of the leading causes of death in intensive care units and, with an estimated price tag of $20 billion in 2011, the most expensive condition that hospitals treat.

3 Dec 2018

Researchers uncover genes that lead to excessive tau in dementia

Researchers have identified two major groups of genes involved in the mutations that lead to excess production of tau, a protein involved in dementia.

3 Dec 2018

Study uncovers how HIV DNA is blocked from entering the cell nucleus

Multiple components of the nuclear pore complex and nuclear import machinery enable a protein called human myxovirus resistance 2 (MX2) to inhibit HIV-1 infection, according to a study published November 29 in the open-access journal PLOS Pathogens by Michael Malim of King’s College London, and colleagues.

3 Dec 2018

Major soil organic matter compound battles chronic wasting disease

A major compound in soil organic matter degrades chronic wasting disease prions and decreases infectivity in mice, according to a study published November 29 in the open-access journal PLOS Pathogens by Judd Aiken of the University of Alberta, and colleagues.

3 Dec 2018

Study provides new insights into how prions enter the brain

The spread of prions to the brain does not occur by direct transmission across the blood-brain barrier, according to a study published November 29 in the open-access journal PLOS Pathogens by Annika Keller and Adriano Aguzzi of the University Hospital Zürich, and colleagues.

3 Dec 2018

CAR T therapy can lead to long-lasting remissions in patients with r/r diffuse large B-cell lymphoma

In an update to a global clinical trial stretching from Philadelphia to four continents, the chimeric antigen receptor (CAR) T cell therapy Kymriah (tisagenlecleucel, formerly CTL019) led to long-lasting remissions in patients with relapsed/refractory (r/r) diffuse large B-cell lymphoma (DLBCL).

3 Dec 2018

Study shows for the first time how a specific cell gene affects transformation of others

An international team of seven institutions from Spain and the US including the University of Valencia has discovered for the first time that the biological activity of the c-MYC gene is necessary so that cell reprogramming occurs, that is, the process by which a specialised cell -for example, a neuron- is transformed into a different cell type.

30 Nov 2018

Researchers identify potential nutritional alternative for people with fish allergy

Fish allergy is one of the most dangerous food allergies, as it is often associated with potentially life-threatening symptoms such as anaphylactic shock.

30 Nov 2018

Protein News and Research

Further Reading

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

Researchers develop new technique to accurately isolate phloem cells across plants

Early gut bacterial colonization may reduce risk of developing eczema

Clearer diagnosis of polio-like illness in young children

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

New study shows that sambaqui societies were not ordinary hunter-gatherers

International study increases group of lung cancer patients who may benefit from immunotherapy

Aerobic exercise may reduce risk of diabetes-related renal disease

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

New strategies may improve performance of CAR-T cell therapy in treating cancer

New drug combination could kill melanoma cells more effectively, study shows

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

Using nanocarrier-delivered microRNA to target sepsis

Researchers uncover genes that lead to excessive tau in dementia

Study uncovers how HIV DNA is blocked from entering the cell nucleus

Major soil organic matter compound battles chronic wasting disease

Study provides new insights into how prions enter the brain

CAR T therapy can lead to long-lasting remissions in patients with r/r diffuse large B-cell lymphoma

Study shows for the first time how a specific cell gene affects transformation of others

Researchers identify potential nutritional alternative for people with fish allergy

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