Genes News and Research

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Transgenomic secures exclusive license from Montefiore for cancer predictive markers

Transgenomic, Inc. announced today that it has acquired an exclusive worldwide license to Montefiore Medical Center's patent application, "Method of Determining the Sensitivity of Cancer Cells to EGFR Inhibitors including cetuximab, panitumumab and erlotinib".

27 May 2011

Insight into new prion formation

Unlocking the mechanisms that cause neurodegenerative prion diseases may require a genetic key, suggest new findings reported by University of Illinois at Chicago distinguished professor of biological sciences Susan Liebman.

27 May 2011

Leukemia, psoriasis drugs may treat vascular diseases

A drug that has been on the market for decades to treat leukemia and skin disorders such as acne and psoriasis may be a possible therapy for vascular diseases, including atherosclerosis and hypertension, which can lead to heart attack or stroke.

27 May 2011

Johns Hopkins announces establishment of new institute for patient safety and quality

Recognizing the urgent need to advance the science of reducing preventable harm and improve health care quality, Johns Hopkins Medicine is announcing the establishment of the Armstrong Institute for Patient Safety and Quality, an organization whose work will benefit not only Johns Hopkins patients but those around the world.

27 May 2011

Berkeley Lab researchers aim to create biological circuits for synthetic biology

Taking a page from the book of San Francisco radio legend Scoop Nisker, biologists who find themselves dissatisfied with the microbes nature has provided are going out and making some of their own. Members of the fast-growing "synthetic biology" research community are designing and constructing novel organisms and biologically-inspired systems - or redesigning existing organisms and systems - to solve problems that natural systems cannot.

27 May 2011

New genomics research on abnormal brain development

Local researchers are finally on the road to developing targeted treatments for serious, life-long disabilities such as autism and schizophrenia, thanks to new genomics research focusing on abnormal brain development.

27 May 2011

Gestational high-fat diet programs woman's baby for future diabetes

A high-fat diet during pregnancy may program a woman's baby for future diabetes, even if she herself is not obese or diabetic, says a new University of Illinois study published in the Journal of Physiology.

26 May 2011

Investigators receive NIH grant to help move gene therapy for MPS IIIB toward clinical trials

Investigators at Nationwide Children's have received a grant from the National Institutes of Health to help move a therapy for MPS IIIB that has been shown effective in mice toward clinical trials in humans.

26 May 2011

New insight into how genes and proteins go awry in autism to alter the mind

For decades, autism researchers have faced a baffling riddle: how to unravel a disorder that leaves no known physical trace as it develops in the brain.

26 May 2011

Taking prenatal vitamins early during pregnancy can reduce risk of having children with autism

Women who reported not taking a daily prenatal vitamin immediately before and during the first month of pregnancy were nearly twice as likely to have a child with an autism spectrum disorder as women who did take the supplements - and the associated risk rose to seven times as great when combined with a high-risk genetic make-up, a study by researchers at the UC Davis MIND Institute has found.

26 May 2011

Coronary artery disease is a leading cause of death in U.S. women

It's a silent killer, most women don't even know they have it. It's often thought of as a man's disease and may not receive as much attention as other illnesses, but coronary artery disease (CAD) is the leading cause of death in women in the U.S. It is so common that if you combine the number of women who die from the next five leading causes of death it would equal the number of women who die from CAD.

26 May 2011

Leukemia protein plays a role in Alzheimer's disease

After decades of studying the pathological process that wipes out large volumes of memory, scientists at The Feinstein Institute for Medical Research discovered a molecule called c-Abl that has a known role in leukemia also has a hand in Alzheimer's disease.

25 May 2011

New combination therapy eradicates acute lymphoblastic leukemia in children, older adults

In a significant breakthrough, investigators at Weill Cornell Medical College and the University of California, San Francisco, have been able to overcome resistance of a form of leukemia to targeted therapy, demonstrating complete eradication of the cancer in cell and animal studies.

25 May 2011

Scientists mimic dyskeratosis congenita through study of undifferentiated iPS cells

A rare genetic disease called dyskeratosis congenita, caused by the rapid shortening of telomeres, can be mimicked through the study of undifferentiated induced pluripotent stem cells, according to new findings from the Stanford University School of Medicine.

24 May 2011

Exosome Diagnostics announces expansion of scientific advisory board

Exosome Diagnostics, a leading developer of biofluid based molecular diagnostic tests for use in personalised medicine, today announced the appointments of Bob Carter MD, Carlos Cordon-Cardo MD, PhD, Keith Flaherty MD, John Quackenbush, PhD; to its Scientific Advisory Board (SAB).

24 May 2011

Research could pave way toward new anti-bacterial treatments

A group of proteins that act as the body's built-in line of defense against invading bacteria use a molecular trick to induce bacteria to destroy themselves, researchers at the Indiana University School of Medicine have determined. The research could point the way toward new anti-bacterial treatments that could take on bacteria that are resistant to antibiotics.

24 May 2011

Researchers replicate progression of inflammatory gene changes of kidney from mild to severe diabetic nephropathy

University of Louisville researchers have replicated the inflammatory gene changes of a human kidney as it progresses from mild to severe diabetic nephropathy, using a mouse model developed by a UofL researcher, according to an article published today in the journal Experimental Nephrology. Diabetic nephropathy is the foremost cause of kidney failure.

24 May 2011

Novel hepatitis C-like virus discovered in dogs

In a study to be published online this week in the Proceedings of the National Academy of Sciences, researchers report the discovery of a novel hepatitis C-like virus in dogs. The identification and characterization of this virus gives scientists new insights into how hepatitis C in humans may have evolved and provides scientists renewed hope to develop a model system to study how it causes disease.

24 May 2011

Mount Sinai researchers identify protein signaling hyperactivity in human sarcoma cells

Researchers from Mount Sinai School of Medicine have discovered a protein signaling pathway that becomes hyperactivated in human sarcoma cells, suggesting that medications to inhibit this pathway may be effective in the treatment of human sarcomas. The research is published in the current issue of the journal Cancer Cell.

24 May 2011

Scientists discover genetic regions that affect severity of cystic fibrosis

A team of international researchers, including Case Western Reserve University School of Medicine, have discovered regions of the genome that affect the severity of the genetic disease cystic fibrosis, the most common lethal genetic disease affecting children in North America.

24 May 2011

Genes News and Research

Transgenomic secures exclusive license from Montefiore for cancer predictive markers

Insight into new prion formation

Leukemia, psoriasis drugs may treat vascular diseases

Johns Hopkins announces establishment of new institute for patient safety and quality

Berkeley Lab researchers aim to create biological circuits for synthetic biology

New genomics research on abnormal brain development

Gestational high-fat diet programs woman's baby for future diabetes

Investigators receive NIH grant to help move gene therapy for MPS IIIB toward clinical trials

New insight into how genes and proteins go awry in autism to alter the mind

Taking prenatal vitamins early during pregnancy can reduce risk of having children with autism

Coronary artery disease is a leading cause of death in U.S. women

Leukemia protein plays a role in Alzheimer's disease

New combination therapy eradicates acute lymphoblastic leukemia in children, older adults

Scientists mimic dyskeratosis congenita through study of undifferentiated iPS cells

Exosome Diagnostics announces expansion of scientific advisory board

Research could pave way toward new anti-bacterial treatments

Researchers replicate progression of inflammatory gene changes of kidney from mild to severe diabetic nephropathy

Novel hepatitis C-like virus discovered in dogs

Mount Sinai researchers identify protein signaling hyperactivity in human sarcoma cells

Scientists discover genetic regions that affect severity of cystic fibrosis

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