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Combination treatment can benefit children with Kawasaki disease

Adding corticosteroids to standard intravenous (IV) immunoglobulin treatment for children with Kawasaki disease judged to be at higher risk of developing blood vessel complications made initial treatment more successful and prevented these complications.

19 Aug 2020

Rare COVID-19 related illness in children causes profound immune changes

Researchers have uncovered how the immune system is altered in a rare COVID-19 related illness in children referred to as paediatric inflammatory multisystem syndrome (PIMS-TS).

18 Aug 2020

ARDS may not be the primary lung iInjury in COVID-19

A new Italian study published on the preprint server medRxiv in August 2020 shows that this may not be an adequate explanation, since ARDS is a nonspecific diagnosis. Instead, they say, antemortem lung biopsy shows a “Covid pattern” of acute lung injury, which could guide the application of therapeutics.

16 Aug 2020

New discoveries could change the understanding and treatment of ovarian cancer

Recent discoveries made by researchers at Texas A&M University could change the way ovarian cancer is understood and treated.

15 Aug 2020

Nanoparticle carriers expand the effectiveness of gene therapies for human eye diseases

NIBIB-funded researchers have created nanoparticles for successful gene therapy of a mouse model of macular degeneration.

15 Aug 2020

Online calculator predicts patients’ risk for ischemic stroke

Doctors can predict patients' risk for ischemic stroke based on the severity of their metabolic syndrome, a conglomeration of conditions that includes high blood pressure, abnormal cholesterol levels and excess body fat around the abdomen and waist, a new study finds.

14 Aug 2020

Dying young: The health care workers in their 20s killed by COVID-19

Jasmine Obra believed that if it wasn't for her brother Joshua, she wouldn't exist. When 7-year-old Josh realized that his parents weren't going to live forever, he asked for a sibling so he would never be alone.

13 Aug 2020

Cardiovascular disease in COVID-19

The current COVID-19 pandemic is a primarily respiratory illness, manifesting with severe hypoxia and often progressing to acute respiratory distress syndrome (ARDS) and death. However, it is also known to be linked to a wide range of cardiovascular (CV) manifestations that are associated with a very poor prognosis.

13 Aug 2020

Reelin inhibition may be effective for treating multiple sclerosis

In an animal model of multiple sclerosis (MS), decreasing the amount of a protein made in the liver significantly protected against development of the disease's characteristic symptoms and promoted recovery in symptomatic animals, UTSW scientists report.

12 Aug 2020

Researchers review scientific articles on proteins that help cancer cells enter the brain

An international team of scientists, including a researcher from Sechenov University, reviewed scientific articles on proteins (and genes encoding them) that help cancer cells enter the brain.

12 Aug 2020

Swapping out red meat for plant-based meat alternatives lowers cardiovascular risk

Now, a new study by researchers at Stanford University School of Medicine has revealed that swapping out red meat for certain plant-based meat alternatives can help improve some cardiovascular risk factors. The use of plant-based alternative meats, there is still limited evidence of the health effects of these products.

12 Aug 2020

Researchers develop fitness app to reduce hospital visits

An app that can measure fitness at home by hospital out-patients is being shared for free by its Malmö University developer. Such technology could be vital in reducing the number of appointments high risk groups must attend.

10 Aug 2020

Scientists identify new treatment targets for blinding retinal disease

When the eye isn't getting enough oxygen in the face of common conditions like premature birth or diabetes, it sets in motion a state of frenzied energy production that can ultimately result in blindness, and now scientists have identified new points where they may be able to calm the frenzy and instead enable recovery

10 Aug 2020

DHODH inhibitor PTC299 shows potential as a COVID-19 therapeutic

As COVID-19 continues to take a heavy toll on human health and life in many parts of the world, there is still no effective antiviral drug or vaccine. This has fueled an intensive search for small molecules and proteins that can inhibit viral entry and replication.

10 Aug 2020

Research identifies a potential therapeutic target for clogged arteries

New work led by Carnegie's Meredith Wilson and Steve Farber identifies a potential therapeutic target for clogged arteries and other health risks that stem from an excess of harmful fats in the bloodstream. Their findings are published by PLOS Genetics.

7 Aug 2020

Immunothrombotic dysregulation is key marker of disease severity in COVID-19

In severe cases of COVID-19, the infection can lead to obstruction of the blood vessels in the lung, heart and kidneys. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have now shown that activated immune cells and blood platelets play a major role in these pathologies.

7 Aug 2020

Researchers use patient-specific tumor organoid to optimize chemotherapy for appendix, colon tumors

A patient-specific tumor organoid model is being used to identify the most effective chemotherapy protocol to treat appendix and colon tumors, a personalized medicine approach that is showing promise.

7 Aug 2020

UArizona researcher aims to deliver statins effectively into the brain of stroke patients

Every year in the United States, about 800,000 people experience a stroke. Many are left with neurological complications such as paralysis on one side of the body, speech and language problems, vision issues, behavioral changes, and memory loss.

6 Aug 2020

Will smoking cannabis harm your heart?, yes says AMA

The American Heart Association (AHA), in their statement, has said that smoking cannabis (marijuana) could be harmful to the heart. This new stand on smoking weed was published this week in the journal Circulation. The announcement is released as an article titled, “Medical Marijuana, Recreational Cannabis, and Cardiovascular Health: A Scientific Statement From the American Heart Association.”

6 Aug 2020

Specific gene impairment may also protect people with Down syndrome

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered that a set of genes with decreased expression in individuals with Down syndrome may lead to clinical abnormalities in this population, such as poor muscle development and heart valve problems.

6 Aug 2020