Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

International Aspirin Foundation introduces two biennial awards

In celebration of the 40th anniversary of the formation of The International Aspirin Foundation, we are delighted to announce the introduction of two biennial awards; a Senior Science Award and a Young Investigator Award.

30 Oct 2014

Game theory and the cancer ecosystem: an interview with Professor Pienta, Johns Hopkins

The classic description of game theory was described by the prisoner's dilemma, which is a situation in which two players have two options where the outcome depends on the simultaneous choice made by the other.

29 Oct 2014

Ludwig researchers discover key mechanism that control plasticity of epithelial cells

Ludwig Oxford researchers have discovered a key mechanism that governs how cells of the epithelia, the soft lining of inner body cavities, shift between a rigid, highly structured and immobile state and a flexible and motile form.

27 Oct 2014

Tiny nano-sized particles may play major role in detecting, tracking breast cancer

Exosomes, tiny, virus-sized particles released by cancer cells, can bioengineer micro-RNA (miRNA) molecules resulting in tumor growth. They do so with the help of proteins, such as one named Dicer. New research from The University of Texas MD Anderson Cancer Center suggests Dicer may also serve as a biomarker for breast cancer and possibly open up new avenues for diagnosis and treatment.

27 Oct 2014

Anti-cancer nanomedicines with smaller sizes exhibit enhanced performance in vivo, show studies

Nanomedicines consisting of nanoparticles for targeted drug delivery to specific tissues and cells offer new solutions for cancer diagnosis and therapy.

17 Oct 2014

Inflammation in tissue creates a niche for cancer cells

In order to invade healthy tissue, tumor cells must leave the actual tumor and enter the bloodstream or lymphatic system. For this purpose, they use certain enzymes, proteases that break down the tissue surrounding the tumor, thus opening the way for tumor cells to reach blood or lymphatic vessels. To keep the proteases in check, the body produces inhibitors such as the protein TIMP-1, which thwart the proteases in their work.

15 Oct 2014

Blocking STAT3 in immune system cells increases anti-tumour immunity

The STAT transcription factors are involved in the development of many forms of cancer. STAT3 is frequently activated in tumour cells, so drugs targeting STAT3 could be used in cancer therapy. However, STAT3 is also important in the development of the immune system. Dagmar Gotthardt and colleagues at the Vetmeduni Vienna now show that blocking STAT3 in cells of the immune system actually leads to increased anti-tumour immunity. Anti-STAT3 therapy may thus be highly promising.

13 Oct 2014

BCRF announces $58.6 million commitment to breast cancer research

The Breast Cancer Research Foundation, announced its dedication of $58.6 million to breast cancer research today at its annual Symposium & Awards Luncheon. Totaling $47 million, the 2014-2015 annual grants, awarded to more than 220 physicians and scientists on six continents, continue to fuel BCRF's mission of advancing the world's most innovative research.

10 Oct 2014

GenomOncology, med fusion partner to optimize treatment strategies for tumor

med fusion, an integrated molecular center of excellence and clinical trials service organization and GenomOncology, an Ohio based genomics technology and services provider, today announced a partnership to optimize treatment strategies based on the patient's disease state and tumor profile.

8 Oct 2014

Researchers discover novel mechanisms of cell migration

During cancer metastasis, immune response or the development of organisms, cells are moving in a controlled manner through the body. Researchers from the Department of Biomedicine at the University of Basel discovered novel mechanisms of cell migration by observing cells moving on lines of connective tissue.

7 Oct 2014

Delta Air Lines kicks off annual campaign to promote awareness on breast cancer

Delta Air Lines' (NYSE: DAL) annual "Breast Cancer One" employee survivor flight took place yesterday, kicking off the airline's month-long campaign to generate awareness and raise money for The Breast Cancer Research Foundation.

1 Oct 2014

Trastuzumab offers better outcome than lapatinib for HER2-positive breast cancer patients

Analysis of more than 8,000 women who participated in the world's largest study of two treatments for HER2-positive breast cancer reinforces other findings from the clinical trial showing that trastuzumab (Herceptin) should remain the standard of care for this cancer, says a Mayo Clinic researcher.

30 Sep 2014

ANN expands commitment to BCRF through annual Breast Cancer Awareness campaign

ANN INC., the parent Company of Ann Taylor and LOFT, today announces its expanded commitment to The Breast Cancer Research Foundation through its annual Breast Cancer Awareness campaign and latest in-store and online promotions.

24 Sep 2014

Alectinib promise for crizotinib-resistant NSCLC

Alectinib has shown promising antitumour activity in patients with ALK-rearranged non-small-cell lung cancer that is resistant to crizotinib, researchers report.

23 Sep 2014

Blocking AEG-1 gene expression halts development of liver cancer by regulating inflammation

Inflammation has been shown to be a driving force behind many chronic diseases, especially liver cancer, which often develops due to chronic inflammation caused by conditions such as viral hepatitis or alcoholism and has relatively few effective treatment options.

23 Sep 2014

Circulating tumour cell clinical research collaboration announced between EKF Diagnostics and Massachusetts General Hospital

EKF, announces that it has entered into a two year research collaboration with Massachusetts General Hospital.

From EKF Diagnostics 23 Sep 2014

Research findings provide avenue for targeted therapy to treat AML

A novel study by the Cancer Science Institute of Singapore at the National University of Singapore found that an increase in a gene known as Leo1 affects other genes that are directly implicated in acute myelogenous leukaemia (AML), increasing the incidence of cancer.

23 Sep 2014

Distinct patterns of gene expression identified in several groups of pancreatic CTCs

Analysis of circulating tumor cells (CTCs) in a mouse model of pancreatic cancer identified distinct patterns of gene expression in several groups of CTCs, including significant differences from the primary tumor that may contribute to the ability to generate metastases.

23 Sep 2014

Immature blood vessels linked to poor sunitinib response

Patients with clear-cell renal cell carcinoma with relatively mature blood vessels respond better to sunitinib and have fewer metastatic sites than those with immature vessels, a study has found.

22 Sep 2014

Researchers develop protein therapy that may stop cancer growth

A team of Stanford researchers has developed a protein therapy that disrupts the process that causes cancer cells to break away from original tumor sites, travel through the blood stream and start aggressive new growths elsewhere in the body.

22 Sep 2014

Metastasis News and Research

Further Reading

International Aspirin Foundation introduces two biennial awards

Game theory and the cancer ecosystem: an interview with Professor Pienta, Johns Hopkins

Ludwig researchers discover key mechanism that control plasticity of epithelial cells

Tiny nano-sized particles may play major role in detecting, tracking breast cancer

Anti-cancer nanomedicines with smaller sizes exhibit enhanced performance in vivo, show studies

Inflammation in tissue creates a niche for cancer cells

Blocking STAT3 in immune system cells increases anti-tumour immunity

BCRF announces $58.6 million commitment to breast cancer research

GenomOncology, med fusion partner to optimize treatment strategies for tumor

Researchers discover novel mechanisms of cell migration

Delta Air Lines kicks off annual campaign to promote awareness on breast cancer

Trastuzumab offers better outcome than lapatinib for HER2-positive breast cancer patients

ANN expands commitment to BCRF through annual Breast Cancer Awareness campaign

Alectinib promise for crizotinib-resistant NSCLC

Blocking AEG-1 gene expression halts development of liver cancer by regulating inflammation

Circulating tumour cell clinical research collaboration announced between EKF Diagnostics and Massachusetts General Hospital

Research findings provide avenue for targeted therapy to treat AML

Distinct patterns of gene expression identified in several groups of pancreatic CTCs

Immature blood vessels linked to poor sunitinib response

Researchers develop protein therapy that may stop cancer growth

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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