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Novel device may simplify monitoring of patients' response to treatment for ovarian cancer

A microchip-based device developed by Massachusetts General Hospital investigators may greatly simplify the monitoring of patients' response to treatment for ovarian cancer - the most lethal form of gynecologic cancer - and certain other malignancies.

6 Dec 2013

Scientists to deliver lecture on innovations in chemistry at ACS meeting

One scientist is developing breakthrough electronic sutures and medical implants that dissolve when their jobs are done. Another is a pioneer in the field of energy conversion that could lead to development of high-performance solar cells and new types of electronic devices that could integrate into the body.

6 Dec 2013

Study focuses on effects of nanoparticles on eosinophils linked to inflammation

In a growing number of industries, workers are often unknowingly exposed to nanoparticles (NPs). Do they enter the body? Could they have an impact on health? Professor Denis Girard from the INRS-Institut Armand-Frappier Research Centre has had the foresight to study the potential toxicity of a wide variety of NPs with a view to setting the record straight before problems occur.

4 Dec 2013

Wrapping in low molecular weight poly can help stabilize hemoglobin

A UConn research team has found a way to stabilize hemoglobin, the oxygen carrier protein in the blood, a discovery that could lead to the development of stable vaccines and affordable artificial blood substitutes.

4 Dec 2013

Drugs delivered by nanoparticles hold promise for targeted treatment of many diseases, including cancer

Drugs delivered by nanoparticles hold promise for targeted treatment of many diseases, including cancer. However, the particles have to be injected into patients, which has limited their usefulness so far.

27 Nov 2013

Seed grants support cancer diagnosis and treatment, vascular health research

Five teams of scientists earned research seed grants awarded this year by the John S. Dunn Foundation. The awards support new collaborations by researchers at Rice University's BioScience Research Collaborative (BRC) and their partners at other institutional members of the Gulf Coast Consortia (GCC).

26 Nov 2013

Waseda University researchers observe molecular motors that play critical role in chromosome transport

Researchers at Waseda University in Japan have for the first time directly observed the “molecular motor”, called Xkid, that plays a critical role in facilitating the proper alignment of chromosomes during cell division. Their findings are expected to contribute greatly to elucidating the molecular mechanisms of chromosome segregation, a key aspect of the development of certain medical disorders including cancer and birth defects.

25 Nov 2013

CHMP adopts positive opinion for ABRAXANE with gemcitabine for treatment of metastatic pancreas

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation, today announced that the European Medicines Agency's: Committee for Medicinal Products for Human Use has adopted a positive opinion for ABRAXANE (paclitaxel formulated as albumin bound nanoparticles, or nab-paclitaxel) in combination with gemcitabine for first-line treatment of adult patients with metastatic adenocarcinoma of the pancreas.

25 Nov 2013

Nanotechnology-based technique: A painless method for maintaining healthy blood sugar levels

A new nanotechnology-based technique for regulating blood sugar in diabetics may give patients the ability to release insulin painlessly using a small ultrasound device, allowing them to go days between injections - rather than using needles to give themselves multiple insulin injections each day.

22 Nov 2013

Probe to measure immune function could lead to determine nanoparticle-based drugs for cancer patients

The development of a probe to measure the body's immune function could lead to more accurate, individualized doses for cancer patients prescribed nanoparticle-based drugs, according to research conducted at the University of North Carolina.

21 Nov 2013

Oxford scientists use nanoparticles to study mechanisms underlying 'mystery' cases of infertility

A way of using nanoparticles to investigate the mechanisms underlying 'mystery' cases of infertility has been developed by scientists at Oxford University.

18 Nov 2013

New technique helps fight deadly pancreatic cancer using 2 types of nanoparticles

Researchers at UCLA's Jonsson Comprehensive Cancer Center have developed a new technique for fighting deadly and hard-to-treat pancreatic cancer that uses two different types of nanoparticles, the first type clearing a path into tumor cells for the second, which delivers chemotherapy drugs.

16 Nov 2013

Sorrento Therapeutics to acquire San Diego-based Concortis Biosystems

Sorrento Therapeutics, Inc. announced today the entry into a definitive agreement to acquire San Diego-based Concortis Biosystems, Corp. in a deal that provides Sorrento with a comprehensive technology platform for generation of antibody drug conjugates (ADC). Under the terms of the agreement dated November 11, 2013, subject to satisfaction of certain closing conditions, upon closing, Sorrento will issue an aggregate of 1,331,978 shares of its common stock to the Concortis shareholders.

14 Nov 2013

Dual-wave nanotherapy method improves treatment of deadly pancreatic cancer

A new method of microscopic drug delivery that could greatly improve the treatment of deadly pancreatic cancer has been proven to work in mice at UCLA's Jonsson Comprehensive Cancer Center.

14 Nov 2013

New biomedical instrument anticipated to help breakthroughs in animal, human health

A Kansas State University team recently received a nearly $1.3 million grant from the National Science Foundation's Major Research Institute for a biomedical instrument that is anticipated to help with breakthroughs in animal and human health as well as cancer treatment.

13 Nov 2013

Nanoparticles with chemotherapeutic drugs can kill drug-resistant breast cancer cells

Nanoparticles filled with chemotherapeutic drugs can kill drug-resistant breast cancer cells, according to a study published in the scientific journal Biomaterials.

8 Nov 2013

New unique nanostructure to target drug-delivery treatment of cancer cells

A unique nanostructure developed by a team of international researchers, including those at the University of Cincinnati, promises improved all-in-one detection, diagnoses and drug-delivery treatment of cancer cells.

29 Oct 2013

Nanomaterials database restructured to improve functionality, add scientific credibility

Nanomaterials are the heart of the smaller, better electronics developed during the last decade, as well as new materials, medical diagnostics and therapeutics, energy storage, and clean water. However, exposure to nanomaterials may have unintended consequences for human health and the environment.

29 Oct 2013

MIT researchers design stealth drug delivery system to attack TNBC cells

Some of the most dangerous cancers are those that can outmaneuver the very drugs designed to defeat them, but researchers are now reporting a new Trojan-horse approach. In a preliminary study in the journal ACS Nano focusing on a type of breast cancer that is highly resistant to current therapies, they describe a way to sneak small particles into tumor cells, lower their defenses and attack them with drugs, potentially making the therapy much more effective.

25 Oct 2013

UMMS professor receives EUREKA grant to develop light activated nanoparticles for imaging brain tissue

University of Massachusetts Medical School Assistant Professor of Biochemistry and Molecular Pharmacology Gang Han, PhD, has received a $1.3 million EUREKA (Exceptional Unconventional Research Enabling Knowledge Acceleration) grant from the National Institute of Mental Health to develop light activated nanoparticles that can be used to image live brain tissue.