OCT News and Research

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UArizona researchers working on a less toxic treatment for deadly breast cancer

After decades of research and two previous drug development attempts, things are looking promising for a team of University of Arizona researchers working on a less toxic treatment for a specific type of breast cancer.

25 Oct 2022

Overexpression of KIF11 gene may offset Alzheimer’s-related cognitive decline in mice and humans

The overexpression of a gene tied to cell division and the structure and function of neurons may prevent and protect against cognitive decline in both mice and humans with Alzheimer’s disease (AD), according to a new study by scientists at the University of Colorado Anschutz Medical Campus.

25 Oct 2022

New approach to immunotherapy provokes a robust anti-tumor immune response in preclinical models

A new approach to cancer immunotherapy that uses one type of immune cell to kill another - rather than directly attacking the cancer - provokes a robust anti-tumor immune response that shrinks ovarian, lung, and pancreatic tumors in preclinical disease models, according to researchers at the Icahn School of Medicine at Mount Sinai in New York.

25 Oct 2022

New evidence on how intermittent fasting impacts women's reproductive hormones

Intermittent fasting has been shown to be an effective way to lose weight, but critics have worried that the practice may have a negative impact on women's reproductive hormones.

25 Oct 2022

Researchers identify specific T cell required to bolster vaccine immunity against fungal pneumonia

Researchers at the University of Illinois College of Veterinary Medicine have demonstrated in a mouse model that a specific type of T cell, one of the body's potent immune defenses, produces cytokines that are necessary for the body to acquire immunity against fungal pathogens.

25 Oct 2022

Researchers set sights on a new therapeutic target for aggressive breast cancer

Researchers at VCU Massey Cancer Center have set their sights on a new therapeutic target for an aggressive form of breast cancer with limited treatment options.

25 Oct 2022

Using a nanotechnology-packed bubble to detect SARS-CoV-2 virus

Scientists have shown that they can detect SARS-CoV-2, the virus that causes COVID-19, in the air by using a nanotechnology-packed bubble that spills its chemical contents like a broken piñata when encountering the virus.

25 Oct 2022

During sleep, the hippocampus and neocortex interact in ways that are key to memory formation

Using a neural network model, Penn neuroscientist Anna Schapiro and colleagues found that as the body moves between REM and slow-wave sleep cycles, the hippocampus and neocortex interact in ways that are key to memory formation.

25 Oct 2022

Geographical location of an individual may determine the likelihood of receiving autism diagnosis

New autism diagnoses tend to be clustered within specific NHS service regions, suggesting that where an individual lives may influence whether they receive an autism diagnosis and access to special education needs support.

25 Oct 2022

Analysis finds link between cumulative occupational exposure and waning lung capacity

Workplace exposure to gases, dusts, fumes, and aromatic solvents used in paints, varnishes, and glues, is linked to waning lung capacity above and beyond that associated with normal aging, finds a pooled data analysis of the available evidence, published online in the journal Occupational & Environmental Medicine.

25 Oct 2022

Brain development determines nap transitions in early childhood

Why do some 4- and 5-year-olds still nap like clockwork every afternoon, while other preschoolers start giving up habitual napping at age 3?

25 Oct 2022

Scientists develop new method to study the proteins released by cells

A new method to study the proteins released by cells, which could lead to the development of new tools to track diseases including cancer, has been developed by scientists at the Francis Crick Institute and Imperial College London.

25 Oct 2022

Harmless group of bacteria linked with increased risk of death in patients with end-stage renal disease

A big group of bacteria found in our soil, our water and our showerheads are harmless for most of us, but a new study indicates they are associated with an increased risk of dying in individuals whose kidneys have failed.

25 Oct 2022

Hospitals said they lost money on Medicare patients. Some made millions, a state report finds.

Atrium Health, the largest hospital system in North Carolina, has declared publicly that in 2019 it provided $640 million in services to Medicare patients that were never paid for, by far the largest "community benefit" it provided that year.

25 Oct 2022

Discovery could affect the search for new Alzheimer's drugs

Alzheimer's disease is associated with a reduction of insulin receptors in brain microvessels, which may contribute to brain insulin resistance and the formation of amyloid plaques, one of the disease's hallmarks.

25 Oct 2022

Study reveals how SARS-CoV-2 infection of macrophages promotes inflammatory responses

Dysregulation of macrophages during SARS-CoV-2 infection and the over-exuberant production of pro-inflammatory cytokines by these macrophages has been hypothesized to contribute to severity of COVID-19 disease.

25 Oct 2022

Large genome-wide association study on nonalcoholic fatty liver disease

Scientists at deCODE genetics in Iceland have discovered rare, protective loss-of-function variants that point to potential drug targets for nonalcoholic fatty liver disease (NAFLD).

24 Oct 2022

Iowa researchers identify neural circuit linked with stress response

At one time or another, we've all felt paralyzed by a threat or danger. University of Iowa researchers have traced where that reaction to a threat arises.

24 Oct 2022

Near-infrared spectroscopy can provide a cost-effective way to noninvasively monitor intracranial pressure

An increase in intracranial pressure (ICP) is a dangerous condition that can be caused by brain bleeds, a brain tumor, cerebral edema, traumatic brain injury, and hydrocephalus.

24 Oct 2022

In utero exposure to flame retardant results in altered brain development in newborn rats

A new study from North Carolina State University shows that exposure in utero to the flame retardant FireMaster 550 (FM 550), or to its individual brominated (BFR) or organophosphate ester (OPFR) components, resulted in altered brain development in newborn rats.

24 Oct 2022

OCT News and Research

UArizona researchers working on a less toxic treatment for deadly breast cancer

Overexpression of KIF11 gene may offset Alzheimer’s-related cognitive decline in mice and humans

New approach to immunotherapy provokes a robust anti-tumor immune response in preclinical models

New evidence on how intermittent fasting impacts women's reproductive hormones

Researchers identify specific T cell required to bolster vaccine immunity against fungal pneumonia

Researchers set sights on a new therapeutic target for aggressive breast cancer

Using a nanotechnology-packed bubble to detect SARS-CoV-2 virus

During sleep, the hippocampus and neocortex interact in ways that are key to memory formation

Geographical location of an individual may determine the likelihood of receiving autism diagnosis

Analysis finds link between cumulative occupational exposure and waning lung capacity

Brain development determines nap transitions in early childhood

Scientists develop new method to study the proteins released by cells

Harmless group of bacteria linked with increased risk of death in patients with end-stage renal disease

Hospitals said they lost money on Medicare patients. Some made millions, a state report finds.

Discovery could affect the search for new Alzheimer's drugs

Study reveals how SARS-CoV-2 infection of macrophages promotes inflammatory responses

Large genome-wide association study on nonalcoholic fatty liver disease

Iowa researchers identify neural circuit linked with stress response

Near-infrared spectroscopy can provide a cost-effective way to noninvasively monitor intracranial pressure

In utero exposure to flame retardant results in altered brain development in newborn rats

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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