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Study identifies genomic regions associated with cholera susceptibility

An international research team has used a novel approach to identify genetic factors that appear to influence susceptibility to cholera. The findings by investigators from Massachusetts General Hospital (MGH), the Broad Institute and the International Center for Diarrh-al Disease Research, Bangladesh (ICDDR,B) indicate the importance of pathways involved in regulating water loss in intestinal cells and of the innate immune system in the body's response to the bacteria that causes cholera, which affects from 3 to 5 million people each year and causes more than 100,000 deaths.

4 Jul 2013

Gerovital H3 may be making a comeback, warns BUSM researcher

Despite it being more than 30 years since the "fountain of youth drug" Gerovital H3 was banned in the United States, it may be making a comeback. In an editorial published in this month's Journal of the American Geriatrics Society BUSM researcher Thomas Perls, MD, points out that a few U.S.-based anti-aging and longevity clinics have begun to advertise Gerovital H3 in pill form and as intravenous infusions despite the fact that the U.S. Food and Drug Administration banned it in 1982.

4 Jul 2013

Updated EULAR recommendations for management of rheumatoid arthritis

The European League Against Rheumatism has released updated recommendations for the management of RA. According to this latest guidance, treatment with disease-modifying anti-rheumatic drugs should be initiated as soon as a diagnosis of RA is made, with the aim of reaching a target of remission or low disease activity in every patient.

4 Jul 2013

FDA approves Orexo's Zubsolv for people suffering from opioid dependence

Orexo today announced that it has received approval from the U.S. Food and Drug Administration for Zubsolv (buprenorphine/naloxone) sublingual tablet CIII.

4 Jul 2013

Royal Philips receives FDA clearance to market AlluraClarity live image guidance system in US

Royal Philips today announced that it has received 510(k) clearance from the US Food and Drug Administration to market its innovative AlluraClarity live image guidance system in the US.

From Philips Healthcare 4 Jul 2013

3-gene signature test will improve care of kidney transplant patients

A breakthrough non-invasive test can detect whether transplanted kidneys are in the process of being rejected, as well as identify patients at risk for rejection weeks to months before they show symptoms, according to a study published in The New England Journal of Medicine (NEJM).

4 Jul 2013

Texas scientists develop new medium for cultivation of beneficial microorganisms

Texas A&M University System scientists from the departments of nutrition and food science and poultry science have developed a new medium for the cultivation of beneficial microorganisms called lactobacilli.

4 Jul 2013

Genentech's obinutuzumab gets FDA Priority Review for chronic lymphocytic leukemia

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration has accepted the company's Biologics License Application for obinutuzumab (GA101) and granted Priority Review for GA101 in the treatment of chronic lymphocytic leukemia, one of the most common forms of blood cancer, based on final Stage 1 data from the pivotal CLL11 trial.

3 Jul 2013

Telemonitoring with pharmacist management improves and maintains BP control

An intervention that consisted of home blood pressure (BP) telemonitoring with pharmacist management resulted in improvements in BP control and decreases in BP during 12 months, compared with usual care, and improvement in BP that was maintained for 6 months following the intervention, according to a study in the July 3 issue of JAMA.

3 Jul 2013

Take time off to mentally rejuvenate and de-stress

To mentally rejuvenate and de-stress, the obvious choice may be to take time off from work or get away from the routine at home with a vacation, but a psychologist at the University of Alabama at Birmingham says a long vacation may not be your best bet.

3 Jul 2013

Biogen, Sobi present new findings from Phase 3 trial of ALPROLIX at XXIV ISTH Congress

Biogen Idec and Swedish Orphan Biovitrum AB (publ) today presented new findings for their long-lasting recombinant factor IX candidate ALPROLIX for hemophilia B at the XXIV International Society on Thrombosis and Haemostasis Congress in Amsterdam, The Netherlands.

3 Jul 2013

Scientists find new links in gene networks that control movement

The idea that worms can be seen as waveforms allowed scientists at Rice University to find new links in gene networks that control movement.

2 Jul 2013

Viewpoints: A 'clever' fix for contraception coverage; Sanjay Gupta warns doctors to pay attention to health overhaul

Many nonprofit religious organizations have balked at having to insure their employees' birth control -- because they don't believe in artificial contraception -- under the Affordable Care Act. On Friday, the Obama administration announced a solution to this problem. The new health care law guarantees access to preventive services, and contraception falls, appropriately, into that category (Carla Hill, 6/28).

2 Jul 2013

UVA researchers identify promising target for treating glioblastoma

Researchers at the University of Virginia Cancer Center have identified a promising target for treating glioblastoma, one that appears to avoid many of the obstacles that typically frustrate efforts to develop effective treatments for this deadliest of cancers.

2 Jul 2013

FDA sends Complete Response Letter to Merck regarding investigational drug for insomnia

Merck, known as MSD outside the United States and Canada, announced today that the company has received a Complete Response Letter from the U.S. Food and Drug Administration (FDA) regarding the New Drug Application for suvorexant, Merck's investigational medicine for the treatment of insomnia.

2 Jul 2013

New UCLA-led study examines content of doctor-patient conversations about dietary supplements

Vitamins, minerals, herbs and other dietary supplements are widely available in supermarkets and drug stores across the nation without a prescription, so it's no surprise that nearly half of all Americans take them.

2 Jul 2013

Genentech's Perjeta regimen gets FDA Priority Review for HER2-positive early stage breast cancer

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration has accepted the company's supplemental Biologics License Application for the use of a Perjeta (pertuzumab) regimen before surgery (neoadjuvant treatment) in people with HER2-positive early stage breast cancer.

2 Jul 2013

Research shows conceptual framework encourages children to eat more vegetables

Every parent has a different strategy for trying to get his or her kid to eat more vegetables, from growing vegetables together as a family to banning treats until the dinner plate is clean. New research suggests that teaching young children an overarching, conceptual framework for nutrition may do the trick.

2 Jul 2013

Pathway Genomics collaborates with Singapore-based company, Parkway Laboratory Services

Pathway Genomics Corporation, a San Diego-based clinical laboratory that offers genetic testing services internationally, has partnered with Parkway Laboratory Services Ltd, an ancillary service of Parkway Pantai Limited, the largest private healthcare provider in Singapore, and one of the largest private healthcare providers in Asia.

1 Jul 2013

Bayer, Onyx submit sNDA to FDA, marketing authorization application to EMA for Nexavar tablets

Bayer HealthCare and Onyx Pharmaceuticals today announced the submission of a supplemental New Drug Application to the U.S. Food and Drug Administration and an application for marketing authorization to the European Medicines Agency for the oral multi-kinase inhibitor Nexavar (sorafenib) tablets for the treatment of locally advanced or metastatic radioactive iodine-refractory differentiated thyroid cancer.

1 Jul 2013

Food News and Research

Study identifies genomic regions associated with cholera susceptibility

Gerovital H3 may be making a comeback, warns BUSM researcher

Updated EULAR recommendations for management of rheumatoid arthritis

FDA approves Orexo's Zubsolv for people suffering from opioid dependence

Royal Philips receives FDA clearance to market AlluraClarity live image guidance system in US

3-gene signature test will improve care of kidney transplant patients

Texas scientists develop new medium for cultivation of beneficial microorganisms

Genentech's obinutuzumab gets FDA Priority Review for chronic lymphocytic leukemia

Telemonitoring with pharmacist management improves and maintains BP control

Take time off to mentally rejuvenate and de-stress

Biogen, Sobi present new findings from Phase 3 trial of ALPROLIX at XXIV ISTH Congress

Scientists find new links in gene networks that control movement

Viewpoints: A 'clever' fix for contraception coverage; Sanjay Gupta warns doctors to pay attention to health overhaul

UVA researchers identify promising target for treating glioblastoma

FDA sends Complete Response Letter to Merck regarding investigational drug for insomnia

New UCLA-led study examines content of doctor-patient conversations about dietary supplements

Genentech's Perjeta regimen gets FDA Priority Review for HER2-positive early stage breast cancer

Research shows conceptual framework encourages children to eat more vegetables

Pathway Genomics collaborates with Singapore-based company, Parkway Laboratory Services

Bayer, Onyx submit sNDA to FDA, marketing authorization application to EMA for Nexavar tablets

Enhancing confidence in chemical ionization spectrometry data eBook

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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