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Domain Therapeutics and Medicxi partner to launch Mavalon Therapeutics

Domain Therapeutics, a biopharmaceutical company that specializes in the discovery and development of G protein-coupled receptor (GPCR) drugs, today announces the creation of Mavalon Therapeutics, a company focused on stopping the progression of Parkinson’s disease.

19 Oct 2016

Biomedical engineers harvest bacterial genes that can improve electrical signaling in human cells

Duke University biomedical engineers have harvested genes for ion channels from bacteria that, with a few tweaks, can create and enhance electrical signaling in human cells, making the cells more electrically excitable.

19 Oct 2016

U-M investigators awarded $7.5 million NIH grant to expand chronic pain research

In order to better understand the disparity between identifiable damage and chronic pain, the National Institutes of Health has awarded $7.5 million over five years to physician-scientists at the University of Michigan Health System.

19 Oct 2016

Mouths of migraine sufferers harbor more nitrate-reducing bacteria, study finds

Researchers at University of California San Diego School of Medicine have found that the mouths of migraine sufferers harbor significantly more microbes with the ability to modify nitrates than people who do not get migraine headaches.

19 Oct 2016

Researchers find new path to stop metastatic growth of cancer

Investigators from the Research Institute of the McGill University Health Centre, and the Institute of Cancer Research, London, have discovered that some cancer cells can draw blood from existing mature blood vessels allowing them to continue to spread.

18 Oct 2016

MIT neuroscientists identify brain cells that play vital role in controlling appetite

MIT neuroscientists have discovered that brain cells called glial cells play a critical role in controlling appetite and feeding behavior.

18 Oct 2016

Study identifies factors that may contribute to use of PIMs at the end of life

A recent interview study has uncovered factors that may contribute to the use of potentially inappropriate medications (PIMs) at the end of life.

18 Oct 2016

SWAT team of immune cells linked to low infection rates after cleft lip and palate surgery in infants

The mouth is widely considered the dirtiest part of the human body, yet babies have surprisingly low infection rates following cleft lip and palate surgery.

18 Oct 2016

Chemotherapy leads to drug-resistance in bladder cancer patients

Chemotherapy is indicated as the first line of treatment for advanced bladder cancer. New research by Weill Cornell Medicine and University of Trento scientists shows that while chemotherapy kills the most common type of bladder cancer, urothelial cancer, chemotherapy also shapes the genetic evolution of remaining urothelial cancer cell clones to become drug-resistant.

18 Oct 2016

Anti-inflammatory drugs may improve severity of depressive symptoms, study finds

Anti-inflammatory drugs similar to those used to treat conditions such as rheumatoid arthritis and psoriasis could in future be used to treat some cases of depression, concludes a review led by the University of Cambridge, which further implicates our immune system in mental health disorders.

18 Oct 2016

Mesh used to reinforce hernia repair provides mixed outcomes, study finds

Among patients undergoing incisional hernia repair, the use of mesh to reinforce the repair was associated with a lower risk of hernia recurrence over 5 years compared with when mesh was not used, although with long-term follow-up, the benefits attributable to mesh were offset in part by mesh-related complications, according to a study published online by JAMA.

18 Oct 2016

Exposure to general anesthesia in young children not linked to long-term effects on brain development

Children who are exposed to general anesthesia from birth to age 2 have developmental testing results in kindergarten that are similar to those of children who have not been exposed, according to a new study published in the October issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists.

18 Oct 2016

Cold medication could suppress spread of bladder cancers

Hokkaido University researchers have discovered that a nonsteroid anti-inflammatory drug used for treating colds suppresses the spread of bladder cancers and reduces their chemoresistance in mice, raising hopes of a future cure for advanced bladder cancers.

17 Oct 2016

Cambridge Cognition announces new contracts for CANTAB Connect for HAL testing of investigational drugs

Cambridge Cognition today announced a series of new contracts for its cloud-based CANTAB Connect software platform for the Human Abuse Liability (HAL) testing of investigational drugs.

17 Oct 2016

Study quantifies burden of adverse drug reactions in general adult population

In a study of 1000 adult patients with unplanned admission to a tertiary hospital in Singapore, the prevalence of adverse drug reactions (ADRs) at the time of admission was 12.4 percent, and the prevalence of ADRs causing admission to the hospital was 8.1 percent.

17 Oct 2016

New stem cell-based strategy may help predict heart-damaging effects of drugs

Coaxing stem cells from patients to become heart cells may help clinicians personalize drug treatments and prevent heart-related toxicity.

17 Oct 2016

Scientists develop software package to predict chemical properties of molecules

Scientists from MIPT's Research Center for Molecular Mechanisms of Aging and Age-Related Diseases together with Inria research center, Grenoble, France have developed a software package called Knodle to determine an atom's hybridization, bond orders and functional groups' annotation in molecules.

17 Oct 2016

Wayne State receives NIH grant to study use of opioid addiction drug to fight relapse in recovering addicts

A team led by Wayne State University School of Medicine researcher Mark Greenwald, Ph.D., will use a four-year, $2,279,723 competitively renewed grant from the National Institute on Drug Abuse of the National Institutes of Health to explore whether the opioid addiction treatment medication buprenorphine can decrease the magnitude and/or duration of responses to stressors faced by recovering addicts.

15 Oct 2016

Immune system plays important role in Duchenne muscular dystrophy, research reveals

A new paper, co-written by faculty at Binghamton University, State University of New York, increases the understanding of Duchenne muscular dystrophy (DMD)—one of the most common lethal genetic disorders—and points to potential therapeutic approaches.

14 Oct 2016

Many Canadian territories restrict access to medications for treating hepatitis C, study finds

A study conducted by Canadian and Australian researchers shows that nearly everywhere in Canada, the provinces and territories impose obstacles to reimbursement of new direct-acting antivirals (DAA) to treat hepatitis C by because of their cost.

14 Oct 2016

Drugs News and Research

Domain Therapeutics and Medicxi partner to launch Mavalon Therapeutics

Biomedical engineers harvest bacterial genes that can improve electrical signaling in human cells

U-M investigators awarded $7.5 million NIH grant to expand chronic pain research

Mouths of migraine sufferers harbor more nitrate-reducing bacteria, study finds

Researchers find new path to stop metastatic growth of cancer

MIT neuroscientists identify brain cells that play vital role in controlling appetite

Study identifies factors that may contribute to use of PIMs at the end of life

SWAT team of immune cells linked to low infection rates after cleft lip and palate surgery in infants

Chemotherapy leads to drug-resistance in bladder cancer patients

Anti-inflammatory drugs may improve severity of depressive symptoms, study finds

Mesh used to reinforce hernia repair provides mixed outcomes, study finds

Exposure to general anesthesia in young children not linked to long-term effects on brain development

Cold medication could suppress spread of bladder cancers

Cambridge Cognition announces new contracts for CANTAB Connect for HAL testing of investigational drugs

Study quantifies burden of adverse drug reactions in general adult population

New stem cell-based strategy may help predict heart-damaging effects of drugs

Scientists develop software package to predict chemical properties of molecules

Wayne State receives NIH grant to study use of opioid addiction drug to fight relapse in recovering addicts

Immune system plays important role in Duchenne muscular dystrophy, research reveals

Many Canadian territories restrict access to medications for treating hepatitis C, study finds

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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