Bleeding News and Research

RSS

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

Doctors worried about dangerous blood clots in patients undergoing a coronary artery procedure— such as angioplasty to treat a heart attack — will often administer antiplatelet therapy to head off complications.

22 May 2016

Inflammatory response prompted by secretion of cytokines causes acid reflux damage in GERD patients

The "acid" in "acid reflux" may not be the direct cause of damage to the esophagus as previously suspected, according to researchers at UT Southwestern Medical Center and Dallas VA Medical Center.

18 May 2016

Japanese surgeons develop new technique to relieve airway obstruction in children

Several pediatric medical conditions, such as congenital heart disease, vascular compression, and congenital softening of the cartilage lining the trachea or bronchi, can compromise the airway and cause breathing difficulty.

18 May 2016

PCI with polymer-free BA9 drug-coated stent better than bare metal stent in ACS patients

Patients with acute coronary syndromes (ACS) who are at high risk for bleeding have significantly lower rates of target lesion revascularisation and fewer adverse events after undergoing percutaneous coronary intervention (PCI) with a polymer-free biolimus-A (BA9) drug-coated stent than with those receiving a bare metal stent (BMS) in results from a sub-study of the LEADERS FREE trial reported for the first time in a late-breaker session at EuroPCR 2016.

17 May 2016

RDAVR system improves survival of patients with severe aortic stenosis

When replacing a defective aortic valve with a new one, restoring function is the first priority. However, variables such as durability, length of surgery, duration of heart stoppage, size of the surgical incision, postoperative pain, and complications are other important considerations.

17 May 2016

Boehringer Ingelheim presents new data on OFEV® (nintedanib) in idiopathic pulmonary fibrosis (IPF)

New analyses presented at the American Thoracic Society’s 2016 annual conference (ATS 2016) further add to the efficacy and safety profile of OFEV® (nintedanib) in idiopathic pulmonary fibrosis (IPF).

16 May 2016

Combination of COX-2-selective NSAID with PPI can reduce risk of stomach, intestinal ulcers

Non-steroidal anti-inflammatory drugs (NSAIDs)—including ibuprofen, diclofenac, naproxen and others—are commonly used pain medications that are generally safe but may increase the risk of developing stomach and intestinal ulcers.

13 May 2016

Important signs, symptoms of stroke that everyone should know

Almost 795,000 Americans suffer from stroke each year, 130,000 which are fatal, making stroke the fifth leading cause of death in the United States.

13 May 2016

Computerized decision support tool can assist physicians in prescribing stroke prevention therapy

Physician-researchers in the College of Medicine at the University of Cincinnati have developed a computerized decision support tool that uses a combination of patient information and characteristics to assist physicians and patients with decisions about blood thinning treatment to prevent strokes in individuals with atrial fibrillation.

12 May 2016

Modified dosage of clot-busting drug can reduce intracerebral haemorrhage

The safety of a controversial clot-busting drug has been investigated by researchers, who have shown a modified dosage can reduce serious bleeding in the brain and improve survival rates.

11 May 2016

Study shows women undergoing TAVR have longer-term survival rate compared to men

Data from one of the largest national registries of transcatheter aortic valve replacement (TAVR) patients shows that although women are more likely to experience vascular complications in the hospital, their one-year survival rate is more favorable than men.

10 May 2016

Younger women more likely to experience one-year adverse cardiovascular events after PCI

Women younger than 55 years of age who undergo percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) are more likely to experience one-year adverse cardiovascular events due to risk factors such as diabetes and chronic kidney disease, yet they are less likely to receive potent antiplatelet therapy than men. The PROMETHEUS study found that outcomes for both men and women post-PCI are dependent on their baseline risk factors, not their sex.

9 May 2016

Novel anticoagulants on ‘as-needed basis’ could be safe alternative to lowering stroke risk

Patients with atrial fibrillation (AF), a rapid irregular heartbeat caused by pooling blood in the heart which can lead to heart failure and stroke, are often treated with an ablation, a minimally invasive procedure used to remove the tissue which causes the pooled blood.

9 May 2016

Study finds no gender-based differences on use of anticoagulation medications in TAVR patients

A study on the impact of using different anticoagulation medications on men and women who have undergone a transcatheter aortic valve replacement (TAVR) found no difference in early vascular complications or mortality.

9 May 2016

Enzyme previously thought beneficial could pose threat to developing embryos

A pair of Oklahoma Medical Research Foundation scientists have discovered that an enzyme previously thought only to be beneficial could, in fact, pose significant danger to developing embryos. The new research could have implications not only for prenatal development but also for treating lymphedema and liver damage resulting from acetaminophen overdose.

5 May 2016

Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Researchers at University of California San Diego School of Medicine have shown that ozanimod (RPC1063), a novel drug molecule, is moderately effective in the treatment of ulcerative colitis. Results of the Phase II clinical trial will appear in the May 5 issue of the New England Journal of Medicine.

5 May 2016

Bayer-new phase 3 liver cancer data

Bayer has announced that a Phase III trial evaluating its oncology compound Stivarga® (regorafenib) tablets for the treatment of patients with unresectable hepatocellular carcinoma (HCC) has met its primary endpoint of a statistically significant improvement in overall survival. The study, called RESORCE, evaluated the efficacy and safety of regorafenib in patients with HCC whose disease has progressed after treatment with sorafenib. The safety and tolerability were generally consistent with the known profile of regorafenib. Detailed efficacy and safety analyses from this study are expected to be presented at an upcoming scientific congress.

4 May 2016

Men need to brush up on their knowledge of skin cancer

Skin cancer can affect anyone, regardless of age, race or gender. When it comes to skin cancer prevention and detection, however, it seems that men need to brush up on their knowledge.

29 Apr 2016

New form of SBRT to deliver radiation to specific area of prostate cancer

University Hospitals Seidman Cancer Center physicians have started the world's first clinical trial using a new form of stereotactic body radiotherapy (SBRT) to deliver radiation to a specific area of the prostate invaded with cancer - instead of the entire gland. The study aims to determine if treating a targeted cancer region within the prostate in early stage prostate cancer can increase treatment options and reduce the side effects of radiation.

28 Apr 2016

New drug combination before surgery may improve outcomes in breast cancer patients

Results from the I-SPY 2 trial show that giving patients with HER2-positive invasive breast cancer a combination of the drugs trastuzumab emtansine (T-DM1) and pertuzumab before surgery was more beneficial than the combination of paclitaxel plus trastuzumab.

19 Apr 2016

Bleeding News and Research

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

Inflammatory response prompted by secretion of cytokines causes acid reflux damage in GERD patients

Japanese surgeons develop new technique to relieve airway obstruction in children

PCI with polymer-free BA9 drug-coated stent better than bare metal stent in ACS patients

RDAVR system improves survival of patients with severe aortic stenosis

Boehringer Ingelheim presents new data on OFEV® (nintedanib) in idiopathic pulmonary fibrosis (IPF)

Combination of COX-2-selective NSAID with PPI can reduce risk of stomach, intestinal ulcers

Important signs, symptoms of stroke that everyone should know

Computerized decision support tool can assist physicians in prescribing stroke prevention therapy

Modified dosage of clot-busting drug can reduce intracerebral haemorrhage

Study shows women undergoing TAVR have longer-term survival rate compared to men

Younger women more likely to experience one-year adverse cardiovascular events after PCI

Novel anticoagulants on ‘as-needed basis’ could be safe alternative to lowering stroke risk

Study finds no gender-based differences on use of anticoagulation medications in TAVR patients

Enzyme previously thought beneficial could pose threat to developing embryos

Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Bayer-new phase 3 liver cancer data

Men need to brush up on their knowledge of skin cancer

New form of SBRT to deliver radiation to specific area of prostate cancer

New drug combination before surgery may improve outcomes in breast cancer patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News