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Study shows how stress has a major impact on the immune system's ability to fight infections

Acute stress can be detrimental to fighting off infection, especially COVID-19, and increases the chance of dying in mouse models.

30 May 2022

Complete Anatomy: Aiming for Education Equality with the World’s Most Advanced Full Female Anatomy Model

In this interview, News Medical speak to Irene Walsh, the director of Product, Design & Content, and 3D4Medical at Elsevier, and Professor Claire Smith, Head of Anatomy at Brighton and Sussex Medical School, about the real-world applications of the Complete Anatomy female model, the most advanced full female anatomy model in the world.

27 May 2022

HMA therapy for patients with myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

26 May 2022

Vitamin D supplements have no clinically meaningful effect in people at high risk of type 2 diabetes

Daily vitamin D supplements do not seem to prevent the development of type 2 diabetes in people already at high risk of the condition, finds a trial from Japan published by The BMJ today.

26 May 2022

HKUMed researchers report the effects of SARS-CoV-2 on bone metabolism

A research team led by Professor Kelvin Yeung Wai-kwok and Dr Jasper Chan Fuk-woo from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that SARS-CoV-2 infection can cause inflammatory activation of bone resorption cells, leading to severe bone loss during the acute and post-recovery phases of COVID-19.

25 May 2022

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Small interfering RNAs, or siRNAs, hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth, without the toxicity that accompanies chemotherapy. However, the siRNAs need a delivery vehicle to protect them from degradation and clearance on their journey through the bloodstream to the cancer tumor.

25 May 2022

Research may lead to new generation of long-lasting medical implants

Scientists from the Tokyo Medical and Dental University used photoelectrochemical measurement and X-ray photoelectron spectroscopy to clarify the source of titanium's biocompatibility when implanted into the body, as with hip replacements and dental implants.

24 May 2022

The Sheri and Les Biller Family Foundation's $10 million gift will support City of Hope’s supportive care program for cancer patients

City of Hope, one of the largest cancer research and treatment organizations in the United States and a national leader in providing cancer patients with best-in-class, integrated supportive care programs, has received a $10 million gift from The Sheri and Les Biller Family Foundation.

24 May 2022

Biologic medications used by IBD patients boost COVID-19 vaccine response

Getting the COVID-19 vaccination strengthened one type of immune response to the SARS-CoV-2 virus in inflammatory bowel disease (IBD) patients even though they were taking immunosuppressant medication, according to investigators at Cedars-Sinai.

23 May 2022

Researchers discover osteogenetic oligodeoxynucleotide that promotes bone differentiation

Bone tissue homeostasis is maintained by a balance between bone formation by osteoblasts and bone resorption by osteoclasts.

23 May 2022

Study: Nearly one-quarter of young sarcoma patients continue to use opioids after treatment completion

New analysis finds more than half of U.S. adolescents and young adults with sarcoma - a type of cancer in the bones or soft tissues - are often prescribed opioids to treat their pain.

23 May 2022

Pfizer COVID-19 vaccine-associated tinnitus responds to transcranial magnetic stimulation

Pfizer-BioNTech COVID-19 vaccine-associated tinnitus was relieved with a brief course of Transcranial Magnetic Stimulation treatment.

23 May 2022

Epilepsy drug inhibits the growth of NF1 tumors in mice

People with neurofibromatosis type 1 (NF1) develop tumors on nerves throughout their bodies. These tumors are usually benign - meaning they don't spread to other parts of the body and are not considered life-threatening - but they can still cause serious medical problems such as blindness, especially when they form in the brain and nerves.

19 May 2022

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Investigators from Rutgers Cancer Institute of New Jersey, New Jersey's only National Cancer Institute- Designated Comprehensive Cancer Center, led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens including microsatellite-stable and unstable (MSI) tumors.

19 May 2022

Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

Glioblastomas (GBMs) are highly aggressive cancerous tumors of the brain and spinal cord. Brain cancers like GBM are challenging to treat because many cancer therapeutics cannot pass through the blood-brain barrier, and more than 90 percent of GBM tumors return after being surgically removed, despite surgery and subsequent chemo- and radiation therapy being the most successful way to treat the disease.

19 May 2022

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Imugene Limited, a clinical stage immuno-oncology company, and City of Hope, one of the largest cancer research and treatment organizations in the United States, today announced that the first patient was dosed in a Phase 1 clinical trial evaluating the safety of novel cancer-killing virus CF33-hNIS VAXINIA when used in people with advanced solid tumors.

18 May 2022

Sonic hedgehog plays key role in the repair strategy of large bone injuries

A USC Stem Cell study in NPJ Regenerative Medicine presents intriguing evidence that large bone injuries might trigger a repair strategy in adults that recapitulates elements of skeletal formation in utero. Key to this repair strategy is a gene with a fittingly heroic name: Sonic hedgehog.

17 May 2022

Many treatments for intracerebral hemorrhage are not as effective as previously thought, guideline suggests

Some treatments or preventive therapies used to manage intracerebral hemorrhages (ICH), or a bleeding stroke, are not as effective as previously believed, according to the new American Heart Association/American Stroke Association guideline for caring for people with spontaneous ICH, published today in the Association's Stroke journal.

17 May 2022

Exposure to cold and warm temperatures causes changes in gene expression in various organs

Human beings, like most organisms, are constantly exposed to alternating colder or warmer temperatures.

17 May 2022

An atlas of human immune cells across tissues

In a recent article published in the Science journal, researchers demonstrated tissue-specific immune cell characteristics in humans by performing cross-tissue immune cell evaluation.

16 May 2022

Bone News and Research

Study shows how stress has a major impact on the immune system's ability to fight infections

Complete Anatomy: Aiming for Education Equality with the World’s Most Advanced Full Female Anatomy Model

HMA therapy for patients with myelodysplastic syndrome could potentially activate a sleeping oncogene

Vitamin D supplements have no clinically meaningful effect in people at high risk of type 2 diabetes

HKUMed researchers report the effects of SARS-CoV-2 on bone metabolism

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Research may lead to new generation of long-lasting medical implants

The Sheri and Les Biller Family Foundation's $10 million gift will support City of Hope’s supportive care program for cancer patients

Biologic medications used by IBD patients boost COVID-19 vaccine response

Researchers discover osteogenetic oligodeoxynucleotide that promotes bone differentiation

Study: Nearly one-quarter of young sarcoma patients continue to use opioids after treatment completion

Pfizer COVID-19 vaccine-associated tinnitus responds to transcranial magnetic stimulation

Epilepsy drug inhibits the growth of NF1 tumors in mice

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Sonic hedgehog plays key role in the repair strategy of large bone injuries

Many treatments for intracerebral hemorrhage are not as effective as previously thought, guideline suggests

Exposure to cold and warm temperatures causes changes in gene expression in various organs

An atlas of human immune cells across tissues

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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