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Shlomo Melmed appointed to Independent Citizen's Oversight Committee

Shlomo Melmed, M.D., senior vice president for academic affairs and dean of the medical faculty at Cedars-Sinai Medical Center, has been appointed by Gov. Arnold Schwarzenegger to the Independent Citizen's Oversight Committee, the governing board of the California Institute for Regenerative Medicine.

7 Aug 2010

Scientists combine basic adipose tissue mass knowledge with clinical experience

These proceedings cover the nervous regulation of both white and brown adipose tissue mass. Different physiological parameters such as metabolism (lipolysis and thermogenesis) and secretory activity (leptin and other adipokines) are reviewed. The plasticity of adipose tissue (proliferation, differentiation and apoptosis) showing the presence of a neural feedback loop between adipose tissue and the brain, which plays a major role in the regulation of energy homeostasis, is discussed.

6 Aug 2010

$Aeterna Zentaris announces $1.5M NIH award for AEZS-108 Phase 1/2 study in refractory prostate cancer$

Aeterna Zentaris announces $1.5M NIH award for AEZS-108 Phase 1/2 study in refractory prostate cancer

Aeterna Zentaris Inc., a late-stage drug development company specialized in oncology and endocrine therapy, today announced that the National Institutes of Health ("NIH") has awarded Dr. Jacek Pinski, Associate Professor of Medicine at the Norris Comprehensive Cancer Center of the University of Southern California, a grant of about US$1.5 million over three years to conduct a Phase 1/2 study in refractory prostate cancer with the Company's doxorubicin LHRH receptor targeted conjugate compound, AEZS-108.

5 Aug 2010

New volume on Growth hormone therapy

Growth hormone (GH) has been used therapeutically for over 50 years. Since the development of a nearly unlimited supply of recombinant human GH in the mid-1980s, children with less severe GH deficiency can also profit from GH replacement therapy.

5 Aug 2010

Study finds higher concentration of endocrine disrupting compounds in indoor air

Homes in low-income and affluent communities in California both had similarly high levels of endocrine disruptors, and the levels were higher in indoor air than outdoor air, according to a new study believed to be the first that paired indoor and outdoor air samples for such wide range (104) of these substances. The study appears in ACS' Environmental Science & Technology, a semi-monthly journal.

5 Aug 2010

Pairing adolescents with college student mentors keeps kids healthy, fit

A program pairing healthy young adults with urban middle school students helped the adolescents adopt healthy habits, active lifestyles and a healthy weight, according to a new study from the University of Maryland School of Medicine. The study, published August 2 in the journal Pediatrics, found that linking African American, inner city adolescents in Baltimore with one-on-one mentorship from college students prevented the schoolchildren from becoming overweight for at least two years after the mentorship experience. Researchers found the adolescents ate fewer snacks and desserts, and engaged in active play more often. The rate of overweight/obesity in the group declined five percent.

3 Aug 2010

Merck reports strong bottom-line performance in second quarter

Merck & Co., Inc. today announced financial results for the second quarter of 2010. The company reported non-GAAP (generally accepted accounting principles) earnings per share (EPS) for the second quarter of $0.86, which excludes purchase accounting adjustments, merger-related expenses, restructuring costs and the gain on AstraZeneca's asset option exercise. Second-quarter GAAP EPS was $0.24.

2 Aug 2010

Abnormal sleep duration adversely affects cardiovascular health

A study in the Aug. 1 issue of the journal Sleep suggests that regularly sleeping for more or less than seven hours per day is associated with an increased risk of cardiovascular disease.

2 Aug 2010

Resveratrol suppresses inflammation in humans: Research

Resveratrol, a popular plant extract shown to prolong life in yeast and lower animals due to its anti-inflammatory and antioxidant properties, appears also to suppress inflammation in humans, based on results from the first prospective human trial of the extract conducted by University at Buffalo endocrinologists.

31 Jul 2010

Resveratrol suppresses inflammation and free radicals: Study

30 Jul 2010

Supplementation of vitamin D protects vascular systems: Study

Vitamin D deficiency is associated with arterial stiffness, a risk factor for heart disease and stroke, in black teens according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). Black teens taking vitamin D supplementation of 2,000 international units (IU) per day had a decrease in central arterial stiffness.

30 Jul 2010

$Postmenopausal women with diabetes taking TZDs at increased fracture risk$

Postmenopausal women with diabetes taking TZDs at increased fracture risk

Postmenopausal women with diabetes taking thiazolidinediones (TZDS), including rosiglitazone and pioglitazone, may be at increased risk for fractures according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). Men with diabetes taking both loop diuretics and TZDs may also be at increased risk of fractures.

29 Jul 2010

New study shows vitamin D deficiency is associated with arterial stiffness

Vitamin D deficiency is associated with arterial stiffness, a risk factor for heart disease and stroke, in black teens according to a new study accepted for publication in The Endocrine Society's www.endo-society.org. Black teens taking vitamin D supplementation of 2,000 international units per day had a decrease in central arterial stiffness.

29 Jul 2010

NPS completes patient randomization in GATTEX Phase 3 study for PN dependent short bowel syndrome

NPS Pharmaceuticals, a specialty pharmaceutical company developing innovative therapeutics for rare gastrointestinal and endocrine disorders, today announced the completion of patient randomization in its Phase 3 registration study of GATTEX® (teduglutide). The double-blind, placebo-controlled safety and efficacy study, which is known as STEPS, is being conducted in patients with parenteral nutrition (PN) dependent short bowel syndrome (SBS) and is now fully randomized with 86 patients.

23 Jul 2010

Researchers identify a stress hormone in sea lamprey

Michigan State University researchers are the first to identify a stress hormone in the sea lamprey, using the 500 million-year-old species as a model to understand the evolution of the endocrine system.

20 Jul 2010

Ronald Reagan UCLA Medical Center ranks first: U.S. News & World Report survey

Ronald Reagan UCLA Medical Center ranks as one of the top five American hospitals -- and the best hospital in the western United States for the 21st consecutive year -- according to a U.S. News & World Report survey that reviewed patient-outcomes data, reputation among physicians and other care-

17 Jul 2010

Impact of circadian dysregulation on mental, physical health

Circadian (daily) rhythms are found in all functions - e.g. performance, mood, endocrine rhythms, behaviour, sleep timing. The biological clocks that control circadian rhythms are based on a genetic programme of interacting molecules in cells throughout the body, coordinated by a ´master clock´ in the brain and synchronised by external cues, mainly light.

16 Jul 2010

Joint statement to help patients, physicians make informed decisions about use of rosiglitazone

The Endocrine Society, American Diabetes Association and American Association of Clinical Endocrinologists issue joint statement in response to an FDA panel's recommendation to keep rosiglitazone (Avandia) on the market

16 Jul 2010

Two-thirds of world's population are vitamin D-insufficient or deficient

Vitamin D surfaces as a news topic every few months. How much daily vitamin D should a person get? Is it possible to have too much of it? Is exposure to the sun, which is the body's natural way of producing vitamin D, the best option? Or do supplements suffice?

16 Jul 2010

Evotec to acquire DeveloGen

Evotec AG today announced the signing of a definitive agreement to acquire DeveloGen, a biopharmaceutical company engaged in the discovery of novel therapeutic approaches for the treatment of metabolic and endocrine disorders, for up to €14m in shares plus performance-related deferred payments (earn-out).

15 Jul 2010