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Spanish-originated SARS-CoV-2 variant A222V shows rapid spread in Lazio, Italy

A startling new study reports the rapid rise to dominance of a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain in Italy. This strain, termed the GV clade, is characterized by a single point mutation.

2 Dec 2020

A new potential COVID-19 vaccine candidate: YF-S0

A recent study published in the journal Nature describes the safety and efficacy of a live-attenuated yellow fever 17D (YF17D) vector-based vaccine candidate expressing a non-cleavable form of the spike protein of severe acute respiratory coronavirus 2 (SARS-CoV2).

2 Dec 2020

Particulate matter levels can play a significant role in SARS-CoV-2 transmission

A new study has found that particulate matter (PM) plays a role in providing surfaces for SARS-CoV-2 transmission and interaction, enabling fomite transmission through deposition.

2 Dec 2020

SARS-CoV-2 deletion mutations may have attenuated infectivity in some strains

A team of researchers at the University of Hong Kong has identified a panel of SARS-CoV-2 variants, called Del-mut, which contains a deletion in the S1/S2 junction. Upon investigating one of the deleted variants in animal models, they found that Del-mut-1 is attenuated in its ability to cause disease or pathological changes.

2 Dec 2020

Autoantigen may help prevent and treat cardiovascular disease

Mitochondrial protein ALDH4A1 has been identified as an autoantigen implicated in atherosclerosis.

2 Dec 2020

Study finds 10 metabolites associated with risk of stroke

Results from a new study are published in Neurology®, which identifies 10 metabolites that are associated with a person’s risk of stroke.

2 Dec 2020

Horizon Discovery licenses CHOSOURCE to Sanyou Biopharmaceuticals Co.

Horizon Discovery today announced that it has granted commercial licenses for its cGMP-compliant CHOSOURCE™ platform to Sanyou Biopharmaceuticals.

From Revvity 2 Dec 2020

Study: Maternal omega-3 deficiency can alter the development of neuronal networks in offspring

Omega-3 fatty acids are essential, necessarily supplied by the diet and indispensable to brain development.

2 Dec 2020

CNRS develops new patented technique that reveals energy status of cells

A procedure that may help personalise anticancer therapies has just been developed by the CNRS, INSERM, and Aix-Marseille University scientists at the Centre d'Immunologie de Marseille-Luminy, in association with colleagues from the University of California San Francisco and the Marseille Public University Hospital System (AP-HM), with support from Canceropôle Provence-Alpes-Côte d'Azur.

2 Dec 2020

Elsevier launches a new book on COVID-19

Elsevier, a global research publishing and information analytics provider, recently launched the English version of COVID-19: The Essentials of Prevention and Treatment. A digital version of the book is freely available to download on Elsevier's Novel Coronavirus Information Center here.

2 Dec 2020

Researchers study SerpinB9 protein that could pave way to new immunotherapy approach

Immunotherapies have transformed the landscape of cancer treatment by allowing physicians to alter or augment patients' immune response to better attack malignant tumors.

2 Dec 2020

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Occasionally, following a transplant procedure, the donor's immune cells recognize the recipient's tissues as foreign and trigger a multisystem disorder called graft-versus-host disease (GVHD).

2 Dec 2020

Cancer cells exhibit metabolic changes that make them vulnerable to ferroptosis

If there is a silver lining in cancer's chaotic biology, it's that the same traits that give cancer cells a growth advantage often present opportunities for sabotaging them.

2 Dec 2020

Researchers devise new molecular imaging strategy to observe the sperm selection process

A protein called CatSper1 may act as a molecular 'barcode' that helps determine which sperm cells will make it to an egg and which are eliminated along the way.

2 Dec 2020

Indiana University researchers report a specific type of childhood cancer

Researchers at Indiana University School of Medicine have published their work about a specific type of childhood cancer in the peer-reviewed, international oncology journal, Cancers.

2 Dec 2020

POSTECH researchers solve the enigma to treating neurological diseases

Neurological diseases of the brain such as dementia, autism and schizophrenia are now a growing social problem. Nevertheless, studies on their definitive cause are still insufficient.

2 Dec 2020

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

A team of San Diego Supercomputer Center (SDSC) researchers recently created a pharmacophore model and conducted data mining of the database of drugs approved by the U.S. Federal Drug Administration (FDA) to find potential inhibitors of papain-like protease of SARS-CoV2, one of the main viral proteins responsible for COVID-19.

2 Dec 2020

Study shows how parasite that causes Chagas disease resists current therapies

New insight on how a parasite can resist current therapies has been published today in the open-access eLife journal.

2 Dec 2020

Immune mechanism in COVID-19 patients triggers cytokine storm

Researchers at the University of São Paulo (USP) in Brazil have demonstrated for the first time that in COVID-19 patients an immune mechanism known as the inflammasome participates in activation of the inflammatory process that can damage several organs and even lead to death.

2 Dec 2020