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BUSM scientists map active human apoptosome to provide better understanding of cell death

Programmed cell death, or apoptosis, plays a central role in the maintenance of human health by providing a line of defense against unrestricted cell growth that occurs in many cancers and AIDS as well as in neurodegenerative diseases and stroke.

4 Oct 2016

Prion proteins can drive emergence of new traits and adaptive opportunities

Prion proteins, best known as the agents of deadly brain disorders like mad cow disease, can help yeast survive hard times and pass the advantageous traits down to their offspring, according to a new study by researchers at the Stanford University School of Medicine.

4 Oct 2016

GDE2 protein could help predict course of neuroblastoma

The research group of Wouter Moolenaar of the Netherlands Cancer Institute (NKI) has, in collaboration with the group of Rogier Versteeg of the AMC Amsterdam, discovered a protein that can predict the course of neuroblastoma.

4 Oct 2016

BUSM scientists discover new strategy to treat colon cancers driven by mutant KRAS genes

Researchers from Boston University School of Medicine have discovered a possible strategy to treat colon cancers that are caused by the mutant KRAS gene, which is responsible for approximately half of all colon cancer cases.

4 Oct 2016

$New review shows both types of diabetes increase risk of fragility fractures$

New review shows both types of diabetes increase risk of fragility fractures

Recent research has shown that bone health is compromised in people with diabetes, resulting in a significantly higher risk of fragility fracture.

4 Oct 2016

HDAC inhibitors show potential to eliminate breast and ovarian cancer stem cells

A group of researchers, led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has shown that histone deacetylase (HDAC) inhibitors have the potential to eliminate stubborn reservoirs of breast and ovarian cancer stem cells (CSCs).

4 Oct 2016

Study highlights impact of cognitive functions on oral cancer treatment

The development of oral cancer drugs as a modality therapy over the last decade has highlighted the problem of non-adherence. Only cancer drugs that are taken can actually work.

4 Oct 2016

New research to explore link between mixed ancestry and reduced chances of developing MND/ALS

Could the key to unlocking the secret of motor neurone disease lie in the collaboration between two small island nations, Ireland and Cuba? Researchers from Trinity College Dublin are heading to Latin America to begin a major new research project which will examine whether the likelihood of developing motor neurone disease (MND/ALS) is reduced in people with mixed ancestral backgrounds.

4 Oct 2016

High out-of-pocket costs may delay Medicare patients' access to novel targeted treatment for cancer

Significant out-of-pocket costs that cancer patients can face before Medicare insurance drug benefits kick in may delay the patients' treatment with a novel class of targeted therapies, according to a University of North Carolina Lineberger Comprehensive Cancer Center-led study.

4 Oct 2016

ACMSD enzyme could become key target for new drugs aimed at preventing suicide

An enzyme called ACMSD—part of a chain of biochemical reactions called the kynurenine pathway, activated by inflammation—could become an important target for new drugs aimed at preventing suicide.

3 Oct 2016

Study finds potential therapeutic target for KRAS-driven cancers

Approximately 20 percent of all human cancers have mutations in a gene called KRAS. KRAS-mutant cancers are among the most difficult to treat, with poor survival and resistance to chemotherapy.

3 Oct 2016

Inhibiting single protein could help restore sensitivity to common treatment for breast cancer

A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found, in animal models of human breast cancer, that inhibiting a single protein restores sensitivity to tamoxifen, a commonly used drug for treatment of some breast cancers.

3 Oct 2016

Researchers discover potential new therapeutic target for treating obesity

Scientists at Baylor College of Medicine, the National Institutes of Health and Virginia Tech Carilion Research Institute have discovered a new mechanism in the mouse brain that regulates obesity.

3 Oct 2016

New molecular biology technique could help identify virus-fighting potential of existing drugs

A new, computer-based screening method could reveal the virus-fighting potential of drugs originally developed to treat other conditions, reports a study in PLOS Computational Biology.

3 Oct 2016

Research shows how new ovarian cancer treatment could help boost anti-tumor immunity

Few effective treatments have been approved to treat ovarian cancer, the deadliest of all cancers affecting the female reproductive system.

3 Oct 2016

Researchers suggest need for human studies to examine effects of cannabinoid use during pregnancy

In this new era of legalized marijuana, far too little research has been conducted on the effect of cannabis on the development of human embryos, say researchers at Georgetown University Medical Center who scoured medical literature on the topic and found what they say is worrisome animal research.

30 Sep 2016

Drugs News and Research

BUSM scientists map active human apoptosome to provide better understanding of cell death

Prion proteins can drive emergence of new traits and adaptive opportunities

GDE2 protein could help predict course of neuroblastoma

BUSM scientists discover new strategy to treat colon cancers driven by mutant KRAS genes

New review shows both types of diabetes increase risk of fragility fractures

HDAC inhibitors show potential to eliminate breast and ovarian cancer stem cells

Study highlights impact of cognitive functions on oral cancer treatment

New research to explore link between mixed ancestry and reduced chances of developing MND/ALS

High out-of-pocket costs may delay Medicare patients' access to novel targeted treatment for cancer

ACMSD enzyme could become key target for new drugs aimed at preventing suicide

Study finds potential therapeutic target for KRAS-driven cancers

Inhibiting single protein could help restore sensitivity to common treatment for breast cancer

Researchers discover potential new therapeutic target for treating obesity

New molecular biology technique could help identify virus-fighting potential of existing drugs

Research shows how new ovarian cancer treatment could help boost anti-tumor immunity

Researchers suggest need for human studies to examine effects of cannabinoid use during pregnancy

Mayo Clinic's biorepository earns CAP accreditation for high-quality operations

Scientists find way to enhance, restore sensitivity to common treatment for breast cancer

FDA recommends consumers to stop using homeopathic teething tablets and gels

Novel bifunctional dimers show promise in preventing Parkinson's disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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