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Anti-malarials most effective in lupus patients genetically at risk of high levels of TNF-alpha

Anti-malarial drugs are most effective in people with lupus who are genetically predisposed to high levels of tumour necrosis factor alpha and low levels of the cytokine IL-10.

16 Feb 2006

Central adiposity, regional fat distribution, and the risk of cholecystectomy in women

A bulging midriff almost doubles a woman's chances of developing gallstones and the need for surgery to remove them, finds an extensive study published ahead of print in Gut.

16 Feb 2006

Less is more hypothesis - gene loss may explain unique human traits

Humans and chimps share most of their genes, yet they differ dramatically in many ways - their walk, the sizes of their brains and their capacities for speech and language, for example.

16 Feb 2006

New way to culture adult stem cells from bone marrow

In a significant advance for regenerative medicine, researchers at Rice University have discovered a new way to culture adult stem cells from bone marrow such that the cells themselves produce a growth matrix that is rich in important biochemical growth factors.

16 Feb 2006

Causes of type 1 diabetes

Scientists are casting a wide, tightly woven net with the goal of catching the causes of type 1 diabetes.

16 Feb 2006

Discovery suggests potential treatment for regenerating nerve tissue after stroke

Researchers at the University of Minnesota Medical School have discovered a new population of cells in human umbilical cord blood that have properties of primitive stem cells.

16 Feb 2006

More pediatricians should counsel children and their parents about preventing skin cancer

More pediatricians should counsel children and their parents about preventing skin cancer, according to dermatology researchers from Wake Forest University Baptist Medical Center. A review of research literature confirmed that prevention should begin in childhood, yet found that the topic is discussed at less than 1 percent of well-child visits.

16 Feb 2006

Taking aim at one of mankind's most common diseases

A detailed structural picture of a molecule that plays a key role in activating the Epstein Barr Virus in human cells has now been obtained by researchers at the European Molecular Biology Laboratory (EMBL) and the Institute of Molecular and Structural Virology (IVMS), associated with the University Joseph Fourier and the CNRS, in Grenoble.

16 Feb 2006

Evidence of link between exposure to aluminium and multiple sclerosis

Scientists at Keele University in Staffordshire have discovered the first evidence of a link between human exposure to aluminium and multiple sclerosis.

16 Feb 2006

Floating reduces stress-related pain

Treatment in the form of floating in huge tanks of saltwater, so-called 'floating', is effective for chronic stress-related pain. This is shown in a study at Karlstad University, Sweden, led by Professor Torsten Norlander.

16 Feb 2006

Hospital admission rates linked to social deprivation, not quality of GP care

Researchers in London have identified a link between increased hospital admission rates for chronic diseases and high levels of material deprivation in the capital.

16 Feb 2006

A high level of education means Alzheimer's hits later, but harder and faster

According to researchers at the Columbia University Medical Center in New York, high levels of education may help ward off Alzheimer’s disease, but they also speed up its progression once the disease has developed.

16 Feb 2006

A new way of recognising DNA

Scientists led by Mike Hannon at the University of Birmingham and Miquel Coll at the Spanish Research Council in Barcelona have discovered a new way that drugs can attach themselves to DNA, which is a crucial step forward for researchers who are developing drugs to combat cancer and other diseases.

16 Feb 2006

Imperial College London, St Mary's and Hammersmith Hospitals consider a merger option

St Mary's and Hammersmith Hospitals NHS Trusts are considering opportunities for closer collaboration.

16 Feb 2006

Stealthyx Therapeutics and Cancer Research Technology announce co-development partnership for tumour-targeted therapy

Cancer Research Technology (CRT), the specialist oncology development and commercialisation company, and Stealthyx Therapeutics, the disease targeting drug company spin out of Queen Mary, University of London have entered into an agreement to co-develop Stealthyx’s proprietary drug delivery platform, Prothyx.

16 Feb 2006

Rifaximin effective in treating flatulence and irritable bowel syndrome

In the first study of its kind, researchers discovered that rifaximin, an antibiotic used to treat diarrhea, is an effective treatment for abdominal bloating and flatulence, including in irritable bowel syndrome (IBS) patients.

16 Feb 2006

The pros and cons of new anti-obesity drug

According to researchers at New York's Columbia University College of Physicians and Surgeons, an anti-obesity drug that turns off the same brain circuits which trigger the marijuana-induced hunger pangs, appears to produce sustained weight loss among patients.

16 Feb 2006

Calcium and Vitamin D supplememts of limited benefit to older women

According to researchers at Stanford University Medical Center, older women who regularly take calcium and Vitamin D marginally decrease their risk of hip fractures.

16 Feb 2006

British woman loses Herceptin court battle

A mother of three in the UK suffering from the early-stage of an aggressive form of breast cancer, has lost her high court battle to force her health authority to pay for the potentially life-saving drug Herceptin.

16 Feb 2006

Measuring levels of NT-proBNP protein predicts long-term risk in patients with shortness of breath

Researchers from Massachusetts General Hospital (MGH) have shown that a blood test previously found useful for diagnosing heart failure and determining prognosis in several cardiovascular conditions can also predict the risk of death among patients coming to hospital emergency departments with shortness of breath.

14 Feb 2006