Drugs News and Research

RSS

Scientists find way to reverse malfunctioning protein clumps involved in ALS

In the quest to understand the driving forces behind neurodegenerative diseases, researchers in recent years have zeroed in on clumps of malfunctioning proteins thought to kill neurons in the brain and spinal cord by jamming their cellular machinery.

22 Sep 2016

CUMC researchers uncover new details of intracellular channel that controls skeletal muscle

Using high-resolution electron microscopy, Columbia University Medical Center researchers have uncovered new details of the structure and function of an intracellular channel that controls the contraction of skeletal muscle.

22 Sep 2016

Scientists identify potential new way to prevent chronic urinary tract infections

Researchers have identified a potential way to prevent chronic urinary tract infections (UTIs). Their research points to a key protein that bacteria use to latch onto the bladder and cause UTIs, according to scientists at Washington University School of Medicine in St. Louis.

22 Sep 2016

JAK inhibitors may be first effective treatment for people with alopecia areata

Seventy-five percent of patients with moderate to severe alopecia areata—an autoimmune disease that causes patchy, and less frequently, total hair loss—had significant hair regrowth after treatment with ruxolitinib, reported researchers from Columbia University Medical Center. By the end of their treatment, average hair regrowth was 92 percent.

22 Sep 2016

Study data does not support benefits of testosterone supplementation in men with ‘low T’

The prescription of testosterone supplementation for cardiovascular health, sexual function, physical function, mood, or cognitive function in men with "low T" is not supported by clinical trials data, conclude researchers who describe a review of more than 200 clinical trials published Sept. 21 in PLOS One.

22 Sep 2016

Scientists discover genomic alterations in pediatric relapsed ALL

A group of researchers from Columbia University, Rutgers University, and institutions in Europe and Japan have identified genomic alterations in pediatric relapsed acute lymphoblastic leukemia (ALL) that cause both therapy resistance and improved clinical response to multi-agent chemotherapy treatment.

22 Sep 2016

Bile acid transporter inhibitors can prevent NASH in mice, study shows

Drugs that interfere with bile acid recycling can prevent several aspects of NASH (nonalcoholic steatohepatitis) in mice fed a high-fat diet, scientists from Emory University School of Medicine and Children's Healthcare of Atlanta have shown.

21 Sep 2016

TSRI scientists shed light on molecular workings of MS drug

A study by scientists at The Scripps Research Institute has helped to de-mystify the molecular workings of the multiple sclerosis (MS) drug Tecfidera. The drug is the most widely prescribed pill-based therapy for MS, but its biological mechanism remains mysterious.

21 Sep 2016

Duke researchers discover blood markers linked to drug-resistant tumor cells

While searching for a non-invasive way to detect prostate cancer cells circulating in blood, Duke Cancer Institute researchers have identified some blood markers associated with tumor resistance to two common hormone therapies.

21 Sep 2016

Experts receive $5.2 million NIH grant to develop affordable test for diagnosing Chagas disease

An international team of researchers led by infectious disease experts at the University of Georgia has received $5.2 million from the National Institutes of Health to develop a more accurate, affordable diagnostic test for Chagas disease, a parasitic infection that kills more than 50,000 people each year in Central and South America.

21 Sep 2016

Study finds nonwhite transplant recipients at risk for skin cancer

A new study from Drexel University College of Medicine suggests all organ transplant recipients, regardless of race, should receive routine, total-body screenings for skin cancer.

21 Sep 2016

Researchers call for transparency of clinical trial data to give clear picture of new treatments

Researchers have called for greater transparency in the public release of clinical trial data after a study revealed significant under-reporting of side effects in medical treatments.

21 Sep 2016

ECTRIMS, EAN collaborate to develop new therapeutic guidelines for MS

The 32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis (MS) concluded today in London (September 14-17) and one of the late breaking sessions presented the Clinical Guideline on the pharmacological management of people with Multiple Sclerosis developed jointly by ECTRIMS and European Academy of Neurology (EAN).

21 Sep 2016

New global health strategy aims to eliminate HCV as global public health threat by 2030

Chronic infection by the hepatitis C virus (HCV) proved fatal for over 700,000 people worldwide in 2013, mainly as a result of liver damage. Although information on the epidemiology of transmission and infection is sparse, recent estimates put the global prevalence of HCV infection at 130-150 million people.

21 Sep 2016

Drugs News and Research

Scientists find way to reverse malfunctioning protein clumps involved in ALS

CUMC researchers uncover new details of intracellular channel that controls skeletal muscle

Scientists identify potential new way to prevent chronic urinary tract infections

JAK inhibitors may be first effective treatment for people with alopecia areata

Study data does not support benefits of testosterone supplementation in men with ‘low T’

Scientists discover genomic alterations in pediatric relapsed ALL

Bile acid transporter inhibitors can prevent NASH in mice, study shows

TSRI scientists shed light on molecular workings of MS drug

Duke researchers discover blood markers linked to drug-resistant tumor cells

Experts receive $5.2 million NIH grant to develop affordable test for diagnosing Chagas disease

Study finds nonwhite transplant recipients at risk for skin cancer

Researchers call for transparency of clinical trial data to give clear picture of new treatments

ECTRIMS, EAN collaborate to develop new therapeutic guidelines for MS

New global health strategy aims to eliminate HCV as global public health threat by 2030

UCSF researchers receive funding from Susan G. Komen to support breast cancer research

Researchers propose new explanation for symptoms of fragile X syndrome

Sticky nanoparticles could play vital role in fighting cancers

CHOP researchers exploit gene discovery in severe epilepsy to identify precision treatment

Gene therapy may be viable approach for treating CF lung problems

AXT to exclusively distribute Unchained Labs biologics research tools in Australia, New Zealand

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News