Lungs News and Research

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Infant respiratory syncytial virus infection results in metabolic reprogramming of airway epithelial cells

Infection with respiratory syncytial virus during infancy results in metabolic reprogramming of epithelial cells lining the airway, according to a Northwestern Medicine study published in the journal Viruses.

20 Nov 2021

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

A nasal COVID vaccine using a weakened influenza vector

The authors of a new study, published on the bioRxiv* preprint server, constructed a COVID-19 nasal vaccine candidate by inserting a gene encoding the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2, named CA4-dNS1-nCoV-RBD (dNS1-RBD) in a live attenuated influenza virus (LAIV) vector.

18 Nov 2021

Study reveals mechanism by which vitamin D reduces inflammation caused by immune cells

Scientists recently gained insights into how vitamin D functions to reduce inflammation caused by immune cells that might be relevant to the responses during severe COVID-19. In a study jointly published by Purdue University and the National Institutes of Health, scientists do just that.

18 Nov 2021

Researchers provide a clearer picture of healthy development of the lungs

Researchers have compiled the most comprehensive road map of the protein composition of human lungs, providing a clearer picture of the healthy development of this essential organ that made terrestrial life possible.

18 Nov 2021

Researchers receive $22 million grant for clinical trial that aims to reduce lung transplant rejection

Physicians at Washington University School of Medicine in St. Louis and Massachusetts General Hospital/Harvard Medical School in Boston have received a seven-year, $22 million grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health to help lead a multicenter clinical trial evaluating whether a novel immunosuppressant can reduce the risk of organ rejection after a lung transplant.

18 Nov 2021

The antiviral function of BET protein against SARS-CoV-2 infection

Considering the past shreds of evidence on BRD2 and BRD4 associated with viral infections, researchers have recently evaluated the function of all relevant BET proteins during COVID-19 infection.

17 Nov 2021

Study reveals complex interplay between diet, gut microbiota, and immune function

The cliché "you are what you eat" has been used for hundreds of years to illustrate the link between diet and health. Now, an international team of researchers has found the molecular proof of this concept, demonstrating how diet ultimately affects immunity through the gut microbiome.

17 Nov 2021

Lung autopsies provide a clearer picture of how SARS-CoV-2 virus spreads and causes damage

Lung autopsy and plasma samples from people who died of COVID-19 have provided a clearer picture of how the SARS-CoV-2 virus spreads and damages lung tissue.

17 Nov 2021

What genes affect the COVID-19 gender imbalance?

Many studies have established that coronavirus disease 2019 (COVID-19) is more infective in men than women, and men are more at risk of severe disease. While some have suggested that behavioral differences could explain increased transmission to men, this does not explain the more morbid prognosis.

16 Nov 2021

A therapeutic interfering particle for SARS-CoV-2

Researchers report their attempt to engineer TIPs that can conditionally replicate with SARS-CoV-2, inhibit viral replication 10–100 fold, and exhibit R0>1.

16 Nov 2021

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Researchers recently conducted a study to identify host factors affecting cellular interactions of the SARS-CoV-2 spike protein.

16 Nov 2021

Study analyzes association between obesity and endothelial dysfunction in COVID-19 patients

In COVID-19 patients, obesity is the factor most associated with the development of endothelial dysfunction, a condition in which the blood vessels become unable to contract and relax adequately, increasing the risk of events such as heart attacks, thrombosis (blood clotting), and stroke.

15 Nov 2021

Exposure to air pollution impacts the brain performance and work capacity

Even short-term exposure to air pollution impacts our brain performance and capacity to work, according to researchers from The University of Queensland and Carnegie Mellon University.

15 Nov 2021

Potential COVID-19 nasal spray vaccine shows promise in mice

A single sniff may one day be all it takes to immunize yourself against COVID-19.

15 Nov 2021

New therapy targets rodents' cells rather than bacterial cells in treating pneumonia

Researchers at the National Institutes of Health have discovered a therapy that targets host cells rather than bacterial cells in treating bacterial pneumonia in rodents.

15 Nov 2021

Could drugs derived from microalgae be effective against COVID-19?

Researchers discuss the ability of some microalgae metabolites to prevent cytokine storm syndrome during COVID-19.

15 Nov 2021

SARS-CoV-2 infection inhibited by CCR2 signaling

A new study discusses the role of monocytes in protecting individuals from SARS-CoV-2.

15 Nov 2021

Updated mapping of the human genetic architecture of COVID-19

In the present study, researchers presented extensive meta-analysis and added ten new genome-wide significant loci.

15 Nov 2021

Type 2 diabetes medication works effectively, safely in patients hospitalized for acute heart failure

Adults treated with empagliflozin during hospitalization for acute heart failure experienced a clinical benefit such as increased survival, lower risk of heart failure hospital readmission and an overall improvement in their quality of life, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2021.

15 Nov 2021

Lungs News and Research

Infant respiratory syncytial virus infection results in metabolic reprogramming of airway epithelial cells

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

A nasal COVID vaccine using a weakened influenza vector

Study reveals mechanism by which vitamin D reduces inflammation caused by immune cells

Researchers provide a clearer picture of healthy development of the lungs

Researchers receive $22 million grant for clinical trial that aims to reduce lung transplant rejection

The antiviral function of BET protein against SARS-CoV-2 infection

Study reveals complex interplay between diet, gut microbiota, and immune function

Lung autopsies provide a clearer picture of how SARS-CoV-2 virus spreads and causes damage

What genes affect the COVID-19 gender imbalance?

A therapeutic interfering particle for SARS-CoV-2

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Study analyzes association between obesity and endothelial dysfunction in COVID-19 patients

Exposure to air pollution impacts the brain performance and work capacity

Potential COVID-19 nasal spray vaccine shows promise in mice

New therapy targets rodents' cells rather than bacterial cells in treating pneumonia

Could drugs derived from microalgae be effective against COVID-19?

SARS-CoV-2 infection inhibited by CCR2 signaling

Updated mapping of the human genetic architecture of COVID-19

Type 2 diabetes medication works effectively, safely in patients hospitalized for acute heart failure

The ultimate guide to lung research tools and protocols eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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