Pharmaceuticals News and Research

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Administering Aspirin at onset of heart attack is standard EMT protocol

New survey results indicate that emergency medical providers are administering aspirin to patients at the onset of a suspected heart attack. McNeil Consumer & Specialty Pharmaceuticals, a division of McNeil-PPC, Inc. and makers of the trusted St. Joseph brand, now make it more convenient and accessible for consumers to take aspirin when faced with a heart attack situation.

24 Aug 2005

New drug that selectively blocks immune responses protects kidneys after transplant

In an international clinical trial, a new drug that selectively blocks immune responses has proved as effective in preventing acute kidney transplant rejection as cyclosporine, the standard anti-rejection treatment.

24 Aug 2005

Disease modifying activity of 2ME2 demonstrated in preclinical rheumatoid arthritis studies

EntreMed a clinical-stage pharmaceutical company developing therapeutics primarily for the treatment of cancer and inflammatory diseases, has announced the presentation of positive preclinical results for its lead compound, 2-methoxyestradiol (2ME2), in models of rheumatoid arthritis.

24 Aug 2005

FDA Approves Aceon to reduce risk of cardiovascular mortality in patients with stable coronary artery disease

Solvay Pharmaceuticals and CV Therapeutics have announced that the U.S. Food and Drug Administration (FDA) has approved Aceon (perindopril erbumine) Tablets for the treatment of patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or non-fatal myocardial infarction (MI).

24 Aug 2005

European Rare Diseases Therapeutic Initiative could provide an important new mechanism for developing new drugs

Because of the very high costs in developing drugs for rare genetic diseases, and the low return on investment, the pharmaceutical industry has rarely developed specific treatments for many of these diseases.

23 Aug 2005

New drug CX717 can temporarily improve performance and reverse the effects of sleep deprivation

Research in monkeys suggests that a new drug can temporarily improve performance and reverse the effects of sleep deprivation on the brain, which would be a breakthrough in helping shift workers, health professionals, military personnel and others who must function at top performance in spite of sleep deficits.

23 Aug 2005

Epidemiological study links heart protection with non-aspirin, non-steroidal drugs

It is well known that aspirin, a non-selective, non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX), reduces the risk of heart attack and stroke.

22 Aug 2005

Chemists synthesize new class of carbenes - potential for pharmaceutical industry

Chemists at the University of California, Riverside have synthesized a new class of carbenes - molecules that have unusual carbon atoms - that is expected to have wide applications in the pharmaceutical industry, ultimately resulting in a reduction in the price of drugs.

22 Aug 2005

Antidepressant drug should have suicide warning for adults as well as children

According to a Norwegian study, adults taking the antidepressant drug paroxetine are at a higher risk of attempting to commit suicide than those not taking medication.

22 Aug 2005

New method to predict protein separation behavior directly from protein structure

Applying math and computers to the drug-discovery process, researchers at Rensselaer Polytechnic Institute have developed a method to predict protein separation behavior directly from protein structure.

22 Aug 2005

Paroxetine linked to higher rate of suicide

Adult patients taking the antidepressant drug paroxetine are at higher risk of attempting to commit suicide than those not taking medication.

22 Aug 2005

Many phase I trials for new cancer fighting drugs never get reported in peer-reviewed journals

A new study finds many phase I trials for new cancer fighting drugs never get reported in peer-reviewed journals, and says investigators should be committed not just to finding novel compounds, but also to make sure final results of their studies be disseminated to the medical community.

22 Aug 2005

Phase I cancer findings under-reported

Phase I cancer studies, trials that are conducted to determine the safety and maximum dose of a new agent, are under-reported in peer-reviewed journals - a trend that could ultimately delay scientific progress and negatively affect patient care, say researchers at The University of Texas M. D. Anderson Cancer Center in a new study out today (Mon., Aug, 22) online in Cancer.

22 Aug 2005

Stem Cell Sciences to commercialise breakthrough in neural stem cell technology

Stem Cell Sciences has announced that it has an exclusive license to a new patented technology to derive and grow neural stem cells. This technology has been licensed from the University of Edinburgh.

16 Aug 2005

Pfizer acquires antibody discovery company Bioren

Pfizer and Bioren today announced the completion of a transaction in which Pfizer purchased all outstanding stock of Bioren for an undisclosed amount.

15 Aug 2005

Abbott receives European approval to market Humira

Abbott has announced that it has received approval from the European Commission to market Humira (adalimumab) as a treatment for psoriatic arthritis and early rheumatoid arthritis (RA) in Europe.

15 Aug 2005

FDA places very tight restrictions on acne drug Accutane

The U.S. Food and Drug Administration said late last week, that in future, patients and doctors will have to register with manufacturers and promise to comply with tight restrictions, before using the acne drug Accutane and it's generic versions.

14 Aug 2005

Researchers have found a signal that could lead to earlier detection and treatment of ovarian cancer

The Penn State team of scientists led by principal investigator Kathleen M. Mulder, Ph.D., professor of pharmacology, and working in conjunction with a researcher from the Center for Cancer Research, National Cancer Institute in Bethesda, Md., studied "km23," a protein that helps to direct protein traffic in the cell.

13 Aug 2005

How some antibiotics kill bacteria

Researchers have uncovered how members of one family of antibiotics kill bacteria that make people sick.

11 Aug 2005

Alternative to Cox II inhibitors

After the failure of cox II inhibitors such as Vioxx, osteoarthritis patients and their doctors are faced with a lack of alternative therapies. The Orthokine-therapy means knee-injections of IL-1Ra protein, obtained from the patient's blood.

11 Aug 2005

Pharmaceuticals News and Research

Administering Aspirin at onset of heart attack is standard EMT protocol

New drug that selectively blocks immune responses protects kidneys after transplant

Disease modifying activity of 2ME2 demonstrated in preclinical rheumatoid arthritis studies

FDA Approves Aceon to reduce risk of cardiovascular mortality in patients with stable coronary artery disease

European Rare Diseases Therapeutic Initiative could provide an important new mechanism for developing new drugs

New drug CX717 can temporarily improve performance and reverse the effects of sleep deprivation

Epidemiological study links heart protection with non-aspirin, non-steroidal drugs

Chemists synthesize new class of carbenes - potential for pharmaceutical industry

Antidepressant drug should have suicide warning for adults as well as children

New method to predict protein separation behavior directly from protein structure

Paroxetine linked to higher rate of suicide

Many phase I trials for new cancer fighting drugs never get reported in peer-reviewed journals

Phase I cancer findings under-reported

Stem Cell Sciences to commercialise breakthrough in neural stem cell technology

Pfizer acquires antibody discovery company Bioren

Abbott receives European approval to market Humira

FDA places very tight restrictions on acne drug Accutane

Researchers have found a signal that could lead to earlier detection and treatment of ovarian cancer

How some antibiotics kill bacteria

Alternative to Cox II inhibitors

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