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UNC researchers map anxiety circuit in the brain that may explain side effects of antidepressants

More than 100 million people worldwide take selective serotonin reuptake inhibitors (SSRIs), such as Prozac and Zoloft, to treat depression, anxiety and related conditions, but these drugs have a common and mysterious side effect: they can worsen anxiety in the first few weeks of use, which leads many patients to stop treatment.

25 Aug 2016

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

An atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects through their actions at different sites on the calcium channel molecule.

25 Aug 2016

Three like-minded nonprofits collaborate to launch immunotherapy clinical trial for pediatric brain tumors

A Kids' Brain Tumor Cure Foundation, Solving Kids' Cancer and the Ty Louis Campbell Foundation announce their joint financial support of a Phase 1 clinical trial to test the safety and efficacy of combination checkpoint inhibitors in the treatment of children with brain tumors.

25 Aug 2016

New imaging technique may help detect amyloid-related heart failure

A type of heart failure caused by a build-up of amyloid can be accurately diagnosed and prognosticated with an imaging technique, eliminating the need for a biopsy, according to a multicenter study led by researchers at Columbia University Medical Center.

24 Aug 2016

Researchers to investigate how physical activity could help individuals with alcohol, substance use disorders

Once the research team has findings, it will share them with health and social service providers, funders, service users and others to gain their views on what the best methods are and to whom they should be offered.

24 Aug 2016

Research findings could lead to new ways of preventing or treating organ transplant rejection

An international team led by researchers from the University of Pittsburgh School of Medicine found that targeting certain donor cells lowered the risk of organ rejection in mice that underwent kidney and heart transplants.

24 Aug 2016

European scientists invent new microscope for rapid detection of deadly infections

A group of European scientists have invented a microscope that will allow the fastest ever detection of life-threatening infections caused by bacteria, such as E. coli or Staphylococcus, and conditions such as Meningitis, saving millions of lives every year.

24 Aug 2016

AgriLife scientists examine role of ghrelin receptor in age-related adipose tissue inflammation in mice

Scientists have proposed that inflammation is the harbinger of aging and central to the aging process, a phenomenon described as 'inflamm-aging,' said Dr. Yuxiang Sun.

24 Aug 2016

Acupuncture may be viable option to manage pain in children with complex medical conditions

It appears that acupuncture may be a viable option for pain management when it comes to pediatric patients who have complex medical conditions, according to new research published by Gillette Children's Specialty Healthcare in St. Paul, Minnesota.

24 Aug 2016

New chemical compound could potentially be used to treat Ebola virus infection

Scientists have found Ebola's Achilles' heel: a new kind of chemical compound can block the protein Ebola uses to break out of cells and infect new cells.

24 Aug 2016

New method estimates patient adherence to antiretroviral drugs

Researchers at the Skaggs School of Pharmacy and Pharmaceutical Sciences at CU Anschutz have developed a technique that estimates an HIVnegative patient's adherence to drugs prescribed to prevent HIV transmission during sex.

24 Aug 2016

Transient dose of rapamycin in middle age can increase life expectancy, improve measures of healthy aging

Geroscience researchers studying the biology of aging briefly treated middle-aged mice with the drug rapamycin to gauge the long-term effects of short-term therapy on health and longevity.

24 Aug 2016

MDI Biological Laboratory researchers receive patent for novel heart disease drug

The U.S. Patent and Trademark Office has announced that it will grant a patent to MDI Biological Laboratory scientists Voot P. Yin, Ph.D., and Kevin Strange, Ph.D., and their collaborator Michael Zasloff, M.D., Ph.D., for use of the small molecule MSI-1436 to stimulate the repair and regeneration of heart tissue damaged by injuries such as a heart attack.

23 Aug 2016

Melatonin appears to suppress growth of breast cancer stem cells

Melatonin, a hormone produced in the human brain, appears to suppress the growth of breast cancer tumors.

23 Aug 2016

TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

The part of the jawbone containing tooth sockets is known as alveolar bone, and its loss over time or following dental disease may ultimately result in tooth loss.

23 Aug 2016

Scientists discover less invasive, cheaper technique to improve woman's chances of becoming pregnant

For those facing infertility, IVF has long been the established option to have a baby. Now Australian and Belgian medical scientists have discovered how to improve a woman's chances of becoming pregnant using a less invasive and cheaper alternative.

23 Aug 2016

Researcher aims to shed new light on inner workings of the retina

One of the more studied parts of the human anatomy, the retina -- the neural layer at the back of the eye that senses light -- still has secrets to reveal.

23 Aug 2016

New drug target could help prevent opioid tolerance and addiction

Researchers have identified a brain mechanism that could be a drug target to help prevent tolerance and addiction to opioid pain medication, such as morphine, according to a study by Georgia State University and Emory University.

23 Aug 2016

Researchers discover new role of cellular signaling molecule involved in release of hunger hormone

Researchers at UT Southwestern Medical Center have identified a previously unknown role of a cellular signaling molecule involved in release of the "hunger hormone" ghrelin, a finding that could have implications for optimal treatment of children taking beta blockers.

23 Aug 2016

New study aims to find how genes that influence brain function cause risk for drug addiction

A new study aims to better understand what makes some individuals particularly vulnerable to developing drug addiction. A team of researchers from across the country will look at how genes that influence brain function cause risk for addictions.

23 Aug 2016

Drugs News and Research

UNC researchers map anxiety circuit in the brain that may explain side effects of antidepressants

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

Three like-minded nonprofits collaborate to launch immunotherapy clinical trial for pediatric brain tumors

New imaging technique may help detect amyloid-related heart failure

Researchers to investigate how physical activity could help individuals with alcohol, substance use disorders

Research findings could lead to new ways of preventing or treating organ transplant rejection

European scientists invent new microscope for rapid detection of deadly infections

AgriLife scientists examine role of ghrelin receptor in age-related adipose tissue inflammation in mice

Acupuncture may be viable option to manage pain in children with complex medical conditions

New chemical compound could potentially be used to treat Ebola virus infection

New method estimates patient adherence to antiretroviral drugs

Transient dose of rapamycin in middle age can increase life expectancy, improve measures of healthy aging

MDI Biological Laboratory researchers receive patent for novel heart disease drug

Melatonin appears to suppress growth of breast cancer stem cells

TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

Scientists discover less invasive, cheaper technique to improve woman's chances of becoming pregnant

Researcher aims to shed new light on inner workings of the retina

New drug target could help prevent opioid tolerance and addiction

Researchers discover new role of cellular signaling molecule involved in release of hunger hormone

New study aims to find how genes that influence brain function cause risk for drug addiction

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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