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Researchers examine different brands of impression materials for border molding in denture fabrication

An edentulous jaw is a condition where either the upper (maxilla) or the lower (mandible) jaw is missing all teeth. In medical practice, it could be treated by placement of a complete denture.

7 Oct 2020

Study reveals potential utility of artemisinin-based treatments against SARS-CoV-2

In a recent, methodologically robust bioRXiv preprint paper, researchers from Germany, Denmark and Hong Kong report in vitro efficacy of extracts from the sweet wormwood plant (Artemisia annua), but also artemisinin, artesunate and artemether derivatives against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Oct 2020

Dried plum diet prevents spinal cord injury‐related bone loss

Findings from a new study among mice show a diet high in dried plum (prunes) completely prevents bone loss associated with spinal cord injury (SCI), while also restoring some of the bone lost following SCI.

6 Oct 2020

Thiopurines could help stop viral replication in human coronaviruses

Researchers from the Department of Microbiology & Immunology, Dalhousie University, University of Calgary, and Department of Biochemistry and Molecular Biology, University of British Columbia, Canada, worked with human coronaviruses in cell cultures to look for drugs that might prevent accumulation and replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Oct 2020

New deep learning-based technique could boost drug development

When you take a medication, you want to know precisely what it does. Pharmaceutical companies go through extensive testing to ensure that you do.

5 Oct 2020

NIST technique could improve detection of SARS-CoV-2 virus

A multidisciplinary research team at the National Institute of Standards and Technology (NIST) has developed a way to increase the sensitivity of the primary test used to detect the SARS-CoV-2 virus, which causes COVID-19.

5 Oct 2020

Researchers find disproportionate public transportation burden on minority neighborhoods

Transportation barriers, such as personal access to a vehicle or public transportation, disproportionally affect minority communities, according to results of a new study presented at the virtual American College of Surgeons (ACS) Clinical Congress 2020.

5 Oct 2020

New approach transforms oldest antibiotics into safer, stronger drugs

Physicians and scientists have long searched the natural world for chemicals that can improve human health. However, evolutionary selection optimized natural chemicals to benefit their host, not for safety or efficacy in humans.

5 Oct 2020

Compounds repurposed from malaria treatment can kill diarrheal pathogen

A class of compounds used for malaria treatment also kill the intestinal parasite Cryptosporidium, a leading cause of diarrheal disease and death in children that has no cure, a multi-institution collaboration of researchers found in a new study.

1 Oct 2020

Researchers identify 'social cells' in the brain linked to social behavior

A research team led by Professor TAKUMI Toru of Kobe University's Graduate School of Medicine (also a Senior Visiting Scientist at RIKEN Center for Biosystems Dynamics Research) have identified 'social cells' in the brain that are related to social behavior. The cells were identified via Ca imaging conducted using a microendoscope .

1 Oct 2020

Sky-high drug prices driven by pharma profits, House Dems charge

Enormous drug company profits are the primary driver of soaring prescription drug prices in America, according to a damning investigation that Democrats on the House Oversight Committee began releasing Wednesday.

30 Sep 2020

Researchers create drug-like compounds to destroy coronavirus' frameshifting element

Scripps Research chemist Matthew Disney, PhD, and colleagues have created drug-like compounds that, in human cell studies, bind and destroy the pandemic coronavirus' so-called "frameshifting element" to stop the virus from replicating.

30 Sep 2020

New porous material enables the degradation of compounds analogous to nerve agents

A team from the Institute of Molecular Science (ICMol) of the University of Valencia has succeeded in synthesizing a new porous material that enables and guides the degradation of compounds analogous to nerve agents used in chemical warfare.

30 Sep 2020

A TLR2 agonist reduces SARS-CoV-2 in upper respiratory tract of ferret model

In a recent bioRxiv* preprint paper, Professor Miles W. Carroll et al. study an agonist for reducing the SARS-CoV-2's viral load. They show that prophylactic intra-nasal administration of TLR2/6 (toll-like receptor) agonist, INNA-051, reduces viral RNA in the nose and throat, in a ferret model.

30 Sep 2020

Novel nasal treatment could protect people from COVID-19

A novel nasal treatment developed to boost the natural human immune system to fight common colds and flu, has proved remarkably successful in reducing COVID-19 viral replication test results, released today, reveal.

30 Sep 2020

Researchers use fruit fly to develop a novel disease model for Pitt-Hopkins syndrome

The researchers from the TalTech molecular neurobiology laboratory headed by professor Tõnis Timmusk used the fruit fly, Drosophila melanogaster to develop a novel disease model for Pitt-Hopkins syndrome (PTHS).

29 Sep 2020

Valproic acid can interact with DNA conformation and regulate gene expression

Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of DNA and regulate gene expression.

29 Sep 2020

Researchers discover specific cellular pathway involved in lung tissue regeneration

Researchers at Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania have identified a cellular pathway that can be targeted with a naturally occurring drug to stimulate lung tissue regeneration, which is necessary for recovery from multiple lung injuries.

28 Sep 2020

Human recombinant soluble ACE2 successfully used in a patient with severe COVID-19

A multinational research group recently published a paper in the journal Lancet Respiratory Medicine which describes the first patient with a severe form of coronavirus disease (COVID-19) that was successfully treated with human recombinant soluble ACE2.

27 Sep 2020

Leica Microsystems Center of Excellence established at Icahn School of Medicine

Icahn School of Medicine at Mount Sinai and Leica Microsystems, Inc. have combined efforts to establish the Leica Microsystems Center of Excellence at Icahn School of Medicine at Mount Sinai.

25 Sep 2020

Compound News and Research

Researchers examine different brands of impression materials for border molding in denture fabrication

Study reveals potential utility of artemisinin-based treatments against SARS-CoV-2

Dried plum diet prevents spinal cord injury‐related bone loss

Thiopurines could help stop viral replication in human coronaviruses

New deep learning-based technique could boost drug development

NIST technique could improve detection of SARS-CoV-2 virus

Researchers find disproportionate public transportation burden on minority neighborhoods

New approach transforms oldest antibiotics into safer, stronger drugs

Compounds repurposed from malaria treatment can kill diarrheal pathogen

Researchers identify 'social cells' in the brain linked to social behavior

Sky-high drug prices driven by pharma profits, House Dems charge

Researchers create drug-like compounds to destroy coronavirus' frameshifting element

New porous material enables the degradation of compounds analogous to nerve agents

A TLR2 agonist reduces SARS-CoV-2 in upper respiratory tract of ferret model

Novel nasal treatment could protect people from COVID-19

Researchers use fruit fly to develop a novel disease model for Pitt-Hopkins syndrome

Valproic acid can interact with DNA conformation and regulate gene expression

Researchers discover specific cellular pathway involved in lung tissue regeneration

Human recombinant soluble ACE2 successfully used in a patient with severe COVID-19

Leica Microsystems Center of Excellence established at Icahn School of Medicine

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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