Leukemia News and Research

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Leukemia (Leukaemia) is a cancer of the blood cells. It is the most common type of blood cancer and affects 10 times as many adults as children. Most people diagnosed with leukemia are over 50 years old. No one knows why some people develop leukemia and others do not. However, scientists have identified some risk factors for the disease. Most people who have known risk factors do not get leukemia, while many who do get the disease have none of these risk factors. During the early stages of leukemia, there may be no symptoms. Many of the symptoms of leukemia don't become apparent until a large number of normal blood cells are crowded out by leukemia cells.

Celator provides update on Phase 3 clinical trial of VYXEOS in patients with untreated high-risk AML

Celator Pharmaceuticals, Inc. today announced that the Phase 3 clinical trial of VYXEOS (cytarabine:daunorubicin) Liposome for Injection (also known as CPX-351) in patients with untreated high-risk (secondary) acute myeloid leukemia (AML) has reached its pre-specified number of events required for the analysis of overall survival.

16 Feb 2016

UAB research reveals heterogonous population of leukemia stem cells

University of Alabama at Birmingham researchers have found a marker on blood cells that may help the most pressing problem in chronic myelogenous leukemia, or CML, today — an inability to get patients off treatment.

16 Feb 2016

Research findings identify potential genetics-guided precision medicine for leukemia patients

An international research team has determined how inherited gene variations lead to severe drug toxicity that may threaten chances for a cure in children with leukemia. St. Jude Children's Research Hospital scientists led the study, results of which set the stage to expand the use of a patient's genetic make-up to tailor chemotherapy.

16 Feb 2016

TUM researchers make progress in bringing immunotherapy to fight against cancer, infectious diseases

The quest to bring immunotherapy into widespread clinical use against cancer and infectious diseases has made great strides in recent years.

15 Feb 2016

NCCN publishes new guidelines with NCCN Evidence Blocks for Breast, Colon, Kidney, and Rectal Cancers

The National Comprehensive Cancer Network has published the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) with NCCN Evidence Blocks™ for Breast, Colon, Kidney, and Rectal Cancers.

15 Feb 2016

Study holds promise for new alternatives to treat leukemia

Researchers at The University of Texas at Austin have discovered that a type of cancer found primarily in children can grow only when signaled to do so by other nearby cells that are noncancerous.

11 Feb 2016

Researchers use hydrogel to prevent stem cells and human embryos from differentiating

Unlike normal cells, stem cells are pluripotent -- they can become any cell type, which makes them powerful potential treatments for diseases such as diabetes, leukemia and age-related blindness. However, maintaining this versatility until the time is right is a major challenge.

11 Feb 2016

Pediatric ALL patients treated with chemotherapy alone at risk for neurocognitive deficits

Pediatric acute lymphoblastic leukemia (ALL) patients treated with chemotherapy alone remain at risk for attention and learning problems that persist after treatment ends, according to St. Jude Children's Research Hospital investigators.

10 Feb 2016

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

North American researchers have identified drugs that showed promising perspectives in treating cancers, according to a recent study published in Cancer Research.

9 Feb 2016

Abnormal breakage of chromosomes in white blood cells triggers aggressive form of ALL

A research team led by St. Jude Children's Research Hospital scientists has discovered details of how the abnormal breakage and rearrangement of chromosomes in white blood cells triggers a particularly aggressive form of acute lymphoblastic leukemia (ALL). Such leukemias are cancers of white blood cells, in which genetic mutations trigger overproduction of immature cells, called lymphoblasts.

9 Feb 2016

New personalized DNA-based digital assay has potential to dramatically impact CML management

The outcomes of chronic myeloid leukemia (CML) have dramatically improved as the result of tyrosine kinase inhibitor (TKI) treatment. Use of a TKI regimen can lower the blood CML biomarker to levels imperceptible by current detection methods. For patients in "molecular remission," however, uncertainties remain regarding whether they will relapse or if treatment should be discontinued.

8 Feb 2016

Bone loss linked with ALL therapy occurs during first month of treatment

Investigators at Children's Hospital Los Angeles have found that significant bone loss - a side effect of chemotherapy for acute lymphoblastic leukemia (ALL) - occurs during the first month of treatment, far earlier than previously assumed. Results of the study will be available online February 4, in advance of publication in the journal Bone.

5 Feb 2016

Researchers discover potential candidates for development of novel targeted therapies for blood cancers

A research team from the Department of Pharmacology and Therapeutics at Roswell Park Cancer Institute has discovered a new class of small-molecule compounds that are good candidates for development of novel targeted therapies in the treatment of leukemia and lymphoma.

28 Jan 2016

Newly drafted consensus statement promotes widespread use of HPV vaccines to prevent cancer

Leaders of several cancer centers designated by the National Cancer Institute have united to support human papillomavirus vaccination. Among them is Cheryl Willman, MD, Director and CEO of the University of New Mexico Comprehensive Cancer Center.

28 Jan 2016

Researchers explore ways to use light to combat cancer

Immunotherapy is one of the hottest emerging areas of cancer research. After all, using the body's own cells to fight cancer can be more effective and less invasive than flooding the entire system with toxic chemicals.

22 Jan 2016

Northwestern researchers use fruit fly genetics to understand how things may go wrong in cancer

Cancer cells are normal cells that go awry by making bad developmental decisions during their lives. In a study involving the fruit fly equivalent of an oncogene implicated in many human leukemias, Northwestern University researchers have gained insight into how developing cells normally switch to a restricted, or specialized, state and how that process might go wrong in cancer.

21 Jan 2016

Health Canada approves immunotherapy clinical study to treat Epstein-Barr virus-related lymphomas

Health Canada recently approved, for the first time in Canada, a clinical project for a Phase I study aimed at treating lymphomas associated with the Epstein-Barr virus (EBV) through adoptive cellular immunotherapy that is specific to EBV.

18 Jan 2016

Researchers reveal totally new biological mechanism that underlies cancer

In a landmark study, researchers from the Broad Institute and Massachusetts General Hospital reveal a completely new biological mechanism that underlies cancer. By studying brain tumors that carry mutations in the isocitrate dehydrogenase (IDH) genes, the team uncovered some unusual changes in the instructions for how the genome folds up on itself.

13 Jan 2016

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

In humans the differentiation of stem cells into hundreds of specialized cell types is vital. Differentiation drives development from fertilized egg to a newborn, and it underlies the continuous replacement of the 5 billion cells that die every hour in an adult. On the downside, mutations in differentiation pathways of different cell types can be drivers of cancers.

13 Jan 2016

McMaster University researchers take a giant leap in detecting early stages of leukemia

McMaster University researchers have taken a giant leap in identifying the early stages of a deadly cancer and predicting how it will develop in individuals.

11 Jan 2016

Leukemia News and Research

Further Reading

Celator provides update on Phase 3 clinical trial of VYXEOS in patients with untreated high-risk AML

UAB research reveals heterogonous population of leukemia stem cells

Research findings identify potential genetics-guided precision medicine for leukemia patients

TUM researchers make progress in bringing immunotherapy to fight against cancer, infectious diseases

NCCN publishes new guidelines with NCCN Evidence Blocks for Breast, Colon, Kidney, and Rectal Cancers

Study holds promise for new alternatives to treat leukemia

Researchers use hydrogel to prevent stem cells and human embryos from differentiating

Pediatric ALL patients treated with chemotherapy alone at risk for neurocognitive deficits

Some heart disease drugs, antibiotics show promising perspectives in treating cancers

Abnormal breakage of chromosomes in white blood cells triggers aggressive form of ALL

New personalized DNA-based digital assay has potential to dramatically impact CML management

Bone loss linked with ALL therapy occurs during first month of treatment

Researchers discover potential candidates for development of novel targeted therapies for blood cancers

Newly drafted consensus statement promotes widespread use of HPV vaccines to prevent cancer

Researchers explore ways to use light to combat cancer

Northwestern researchers use fruit fly genetics to understand how things may go wrong in cancer

Health Canada approves immunotherapy clinical study to treat Epstein-Barr virus-related lymphomas

Researchers reveal totally new biological mechanism that underlies cancer

New mechanism of differentiation may offer novel therapeutic approaches to blood malignancies, solid tumors

McMaster University researchers take a giant leap in detecting early stages of leukemia

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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