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Small piece of RNA plays big role in development of IPF: Researchers

A small piece of RNA appears to play a big role in the development of idiopathic pulmonary fibrosis (IPF), according to lung disease researchers at the University of Pittsburgh School of Medicine. Their study, which is the first to examine microRNAs in the disease, is available online in the American Journal of Respiratory and Critical Care Medicine.

29 Apr 2010

China lifts decades-old HIV/AIDS travel ban

Late Tuesday, China's State Council lifted a decades-old restriction that banned foreigners with HIV/AIDS from entering the country, Reuters reports (Buckley, 4/27). The amended rules, which appear on the government website, also lift a travel ban on foreigners with other sexually transmitted diseases and leprosy, and "narrow the travel restriction on people with tuberculosis, to those with an infectious form of the lung disease," according to Bloomberg Businessweek (Randall, 4/28).

29 Apr 2010

Study confirms utility of Oxford Immunotec's T-SPOT.TB assay in identifying latent TB infection

The authors of a recent peer-reviewed study published in the International Journal of Tuberculosis and Lung Disease confirmed the high specificity of the T-SPOT.TB assay.

26 Apr 2010

Children born very early have abnormal lung function: U.K. researchers

More than half of children who were born very early—at 25 weeks or less (normal gestation is around 40 weeks)— have abnormal lung function and are twice as likely as their full-term peers to have a diagnosis of asthma, according to U.K. researchers, who followed a national cohort of extremely preterm infants to age 11.

22 Apr 2010

Initial results of gallium-containing compound to treat serious infection presented at AACR 2010

Genta Incorporated today announced the presentation of initial results from the first human use of a gallium-containing compound to treat serious infection. In a patient with cystic fibrosis and a highly resistant lung infection, who has been treated over a 2-year period, high concentrations of gallium were achieved in sputum.

21 Apr 2010

End-of-life care documentation helps in emergency treatment decisions

When Heather Rubesch was a teenager, her aunt died in need of a kidney transplant. In later family discussions, Heather's mother, Linda, expressed some of her views about end-of-life care—for instance, her belief in organ donation.

19 Apr 2010

Tools and applications of QI methodology in Neonatal-Perinatal practice

The March 2010 issue of Clinics in Perinatology, published by Elsevier, provides Neonatologists and Maternal-Fetal-Medicine specialists with the tools and concepts necessary to understand Quality Improvement (QI) methodology and to initiate QI projects within their own practices and neonatal intensive care units (NICUs).

17 Apr 2010

Breathe California names CODA Automotive as winner of Clean Air Award

CODA Automotive, a California-based electric car and battery company, was named a Clean Air Award winner in the technology development category by Breathe California. The award, presented today in San Francisco, highlights standout efforts to combat climate change and air pollution in the business, government, education and non-profit sectors.

17 Apr 2010

Research roundup: Revamping NCI Clinical Trials, reducing malpractice suits, health disparities persist

A National Cancer Clinical Trials System For The 21st Century: Reinvigorating The NCI Cooperative Group Program - The "system for conducting cancer clinical trials in the United States is approaching a state of crisis," according to this report on inefficiencies and funding issues faced by the NCI's Clinical Trials Cooperative Group Program - which comprises 10 groups, more than 3,100 institutions, 14,000 investigators and more than 25,000 patients in clinical trials each year.

17 Apr 2010

Volcanic ash falls across Europe

Flights were cancelled across Europe today thanks to volcanic ash drifting in to northern Europe from Iceland. More than 250 flights were grounded from London’s Gatwick and Heathrow airports alone, leaving thousands of passengers stranded. The ash is drifting in from a volcanic eruption in Iceland and the cloud is capable of damaging jet engines that travel through it.

16 Apr 2010

Stem cell scientists receive stimulus grants to study lung and blood disorders

Stem cell scientists at The University of Texas Health Science Center at Houston (UTHealth) were awarded stimulus grants totaling almost $2 million to research experimental treatments for blood disorders and inherited lung diseases affecting children.

13 Apr 2010

Three nonprofit organizations launch campaign to increase national awareness of PF

The Coalition for Pulmonary Fibrosis, The Pulmonary Fibrosis Foundation and the Pulmonary Fibrosis Association of Texas today announced the launch of a special, grassroots campaign to build increased national awareness of Pulmonary Fibrosis.

12 Apr 2010

Study provides benchmark data to evaluate quality of management of sickle cell disease

The largest study to date of the use of acute care medical services by people with sickle cell disease found four of every 10 had to return to the hospital within 30 days of a previous hospitalization or go to the emergency department for treatment of pain, according to a new study funded in part by HHS' Agency for Healthcare Research and Quality.

7 Apr 2010

Sickle cell disease: Rehospitalization rates high

7 Apr 2010

Two Phase I studies of Stedivaze demonstrate safety in patients with asthma and COPD

Clinical Data, Inc., today announced results from two Phase I studies of Stedivaze™ (apadenoson), which demonstrated that Stedivaze was safe and well tolerated in patients with asthma and chronic obstructive pulmonary disease (COPD). Stedivaze is a potent and highly selective agonist of the adenosine A2A receptor subtype in development as a pharmacologic stress agent for myocardial perfusion imaging (MPI).

30 Mar 2010

Positive results from Pearl Therapeutics' Phase 1 study of inhaled combination bronchodilator for COPD

Pearl Therapeutics Inc., a company developing clinically differentiated combination therapies for the treatment of highly prevalent chronic respiratory diseases, today announced positive results from a Phase 1 safety and pharmacokinetics study of PT003, its lead combination therapeutic for the treatment of chronic obstructive pulmonary disease (COPD). Based on these results, and previously announced positive results from Phase 2a studies of PT003's individual components, the company has advanced PT003 into a Phase 2b trial.

29 Mar 2010

EMA validates InterMune's pirfenidone MAA for IPF

InterMune, Inc. today announced that the company's Marketing Authorization Application (MAA), submitted on March 2 seeking approval of pirfenidone for the treatment of idiopathic pulmonary fibrosis (IPF) in adults, was validated by the European Medicines Agency (EMA). Validation of the MAA by the EMA indicates that the application is complete and that the review process will begin on March 24. The proposed trade name for pirfenidone in both the United States and Europe is Esbriet®.

23 Mar 2010

Safe to smoke?

Some Australian scientists have found that there is a new agent that can protect the lungs of mice from the harmful effects of cigarette smoke.

19 Mar 2010

Blocking GM-CSF could reduce inflammation and deleterious effects of cigarette smoke exposure

Researchers in Australia have demonstrated that blocking a certain protein can reduce or prevent cigarette smoke-induced lung inflammation in mice. Inflammation underlies the disease process of chronic obstructive pulmonary disease (COPD) and many other smoking-related ailments.

18 Mar 2010

Research data: WTC collapse caused potentially dangerous heart problems in responders on-site

Researchers from Mount Sinai School of Medicine are presenting more than 20 ground-breaking studies at the American College of Cardiology 59th annual scientific session (ACC.10) in Atlanta. Their research includes data showing that the World Trade Center collapse has caused potentially dangerous heart problems in responders on-site.

17 Mar 2010

Lung Disease News and Research

Small piece of RNA plays big role in development of IPF: Researchers

China lifts decades-old HIV/AIDS travel ban

Study confirms utility of Oxford Immunotec's T-SPOT.TB assay in identifying latent TB infection

Children born very early have abnormal lung function: U.K. researchers

Initial results of gallium-containing compound to treat serious infection presented at AACR 2010

End-of-life care documentation helps in emergency treatment decisions

Tools and applications of QI methodology in Neonatal-Perinatal practice

Breathe California names CODA Automotive as winner of Clean Air Award

Research roundup: Revamping NCI Clinical Trials, reducing malpractice suits, health disparities persist

Volcanic ash falls across Europe

Stem cell scientists receive stimulus grants to study lung and blood disorders

Three nonprofit organizations launch campaign to increase national awareness of PF

Study provides benchmark data to evaluate quality of management of sickle cell disease

Sickle cell disease: Rehospitalization rates high

Two Phase I studies of Stedivaze demonstrate safety in patients with asthma and COPD

Positive results from Pearl Therapeutics' Phase 1 study of inhaled combination bronchodilator for COPD

EMA validates InterMune's pirfenidone MAA for IPF

Safe to smoke?

Blocking GM-CSF could reduce inflammation and deleterious effects of cigarette smoke exposure

Research data: WTC collapse caused potentially dangerous heart problems in responders on-site

The ultimate guide to lung research tools and protocols eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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