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Burnout threatens primary care workforce and doctors’ mental health

Melanie Gray Miller, a 30-year-old physician, wiped away tears as she described the isolation she felt after losing a beloved patient.

7 Jun 2023

Single dose of anti-Müllerian hormone gene therapy can induce long-term contraception in domestic cats

Currently there are no contraceptives capable of producing permanent sterilization in companion animals. Spaying, the surgical removal of the ovaries and uterus, is the most widely used strategy to control unwanted reproduction in female cats.

6 Jun 2023

As fewer MDs practice rural primary care, a different type of doctor helps take up the slack

For 35 years, this town's residents have brought all manner of illnesses, aches, and worries to Kevin de Regnier's storefront clinic on the courthouse square — and he loves them for it.

6 Jun 2023

Large-scale comprehensive sequencing helps downstream medical care in newborns

Researchers who lead the world's first comprehensive sequencing program for newborn infants have published the next chapter in the ongoing study of the BabySeq Project, with new findings on infants and families who have been followed for 3-5 years.

6 Jun 2023

Cure Mito Foundation releases the first-of-its-kind online resource about Leigh syndrome

The Cure Mito Foundation, a parent-led organization dedicated to advancing research and treatments for Leigh syndrome, has launched the first-of-its-kind online resource about Leigh syndrome, the most common type of pediatric mitochondrial disease.

5 Jun 2023

Stopping treatment at two years does not seem to compromise overall survival in patients with advanced lung cancer

Over the past decade, the approval of immune checkpoint inhibitors has revolutionized treatment for patients with advanced lung cancer, helping many live longer lives and improving overall survival for the disease.

4 Jun 2023

Study of immunotherapy for brain cancer metastases shows promising results

In a phase 2 clinical trial of the immune checkpoint inhibitor pembrolizumab, investigators found that 42 percent of patients with metastatic brain cancer benefited from the therapy, with seven patients in the trial surviving longer than two years.

2 Jun 2023

How does a riboswitch regulate its own synthesis?

To prevent a global health crisis, scientists around the world are searching for ways to fight bacteria that can evade the current arsenal of antibiotics.

2 Jun 2023

Fentanyl could be weaponized and used for terroristic mass poisoning

The widely-available drug fentanyl, already the number one killer of Americans under 50, could be weaponized and used for terroristic mass poisoning, according to health experts at Rutgers and other institutions.

1 Jun 2023

Scientists develop new immuno-therapeutic approach to target brain metastatic melanomas

Acting as a team, twin stem cells activate the immune system to suppress tumor growth and prolong survival in representative preclinical models.

31 May 2023

Important discovery could lead to new treatments for obesity and related diseases

Researchers at the University of East Anglia and the University of Cambridge have made an important discovery in the race to find treatments for obesity and related diseases, such as diabetes.

31 May 2023

Aggressive lung pathogen may not be prone to person-to-person transmission

A little-known bacterium - a distant cousin of the microbes that cause tuberculosis and leprosy - is emerging as a public health threat capable of causing severe lung infections among vulnerable populations, those with compromised immunity or reduced lung function.

30 May 2023

Alternative gene splicing can impact the risk for alcohol use disorder

Researchers at Indiana University School of Medicine have discovered alternative gene splicing, which occurs during gene expression, can impact a person's risk of alcohol use disorder (AUD).

30 May 2023

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

To commemorate World Multiple Sclerosis (MS) Day, we speak to Dr. Cameron McAlpine about his latest research that sought to understand better the proteins and signals that act as messengers between brain and immune cells in MS.

30 May 2023

Novel treatment targets against natural killer/T-cell lymphoma identified

A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore has discovered that a transcription factor, TOX2, was aberrantly increased in patients with Natural killer/T-cell lymphoma (NKTL).

29 May 2023

Research could help develop better treatments for swallowing disorders

Sensory cells in the vagus nerve can detect and locate food in the esophagus. Their signals help transport the food onward to the stomach. Signal failure leads to swallowing disorders, say a team led by Carmen Birchmeier at the Max Delbrück Center.

26 May 2023

Kentucky, Michigan scientists receive American Heart Association Merit Award for cardiovascular research

A Lexington, Ky., research scientist studying ways to repair damaged major vessels with medication rather than surgery and a physician-scientist from Ann Arbor, Mich., exploring the mechanisms of how exercise can heal heart muscle and brain tissue following a heart attack or stroke are the most recent American Heart Association Merit Award recipients.

26 May 2023

Medical School News and Research

Burnout threatens primary care workforce and doctors’ mental health

Single dose of anti-Müllerian hormone gene therapy can induce long-term contraception in domestic cats

As fewer MDs practice rural primary care, a different type of doctor helps take up the slack

Large-scale comprehensive sequencing helps downstream medical care in newborns

Cure Mito Foundation releases the first-of-its-kind online resource about Leigh syndrome

Stopping treatment at two years does not seem to compromise overall survival in patients with advanced lung cancer

Study of immunotherapy for brain cancer metastases shows promising results

How does a riboswitch regulate its own synthesis?

Fentanyl could be weaponized and used for terroristic mass poisoning

Scientists develop new immuno-therapeutic approach to target brain metastatic melanomas

Important discovery could lead to new treatments for obesity and related diseases

Aggressive lung pathogen may not be prone to person-to-person transmission

Alternative gene splicing can impact the risk for alcohol use disorder

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Novel treatment targets against natural killer/T-cell lymphoma identified

Research could help develop better treatments for swallowing disorders

Kentucky, Michigan scientists receive American Heart Association Merit Award for cardiovascular research

Tracking changes in blood vessels may hold clues to early detection of neurodegenerative diseases

RECOVER study: An important step toward defining long COVID

Identifying what makes some gut bacteria strains life-threatening in pre-term babies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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