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Multinational study suggests new way to classify gliomas

A comprehensive analysis of the molecular characteristics of gliomas—the most common malignant brain tumor—explains why some patients diagnosed with slow-growing (low-grade) tumors quickly succumb to the disease while others with more aggressive (high-grade) tumors survive for many years.

29 Jan 2016

Researchers create new neuronal connections for the first time

That very fine hair-line object that you see being pulled across the screen is actually a neuron being made. A research team led by McGill University and the Montreal Neurological Institute has managed to create new functional connections between neurons for the first time. Apart from the fact that these artificial neurons grow over 60 times faster than neurons naturally do, they are indistinguishable from ones that grow naturally in our bodies.

29 Jan 2016

Three Case Western faculty members receive funding to develop new diagnostic technologies

Three Case Western Reserve University faculty members have received funding to further develop emerging technologies aimed at malaria, cystic fibrosis, and sickle cell anemia.

29 Jan 2016

Study provides detailed new information about diffuse glioma

An international collaborative study has revealed detailed new information about diffuse glioma, the most common type of tumor found in some 80 percent of adult brain cancer patients, raising hopes that better understanding of these disease groups may aid improved clinical outcomes.

29 Jan 2016

Three RIT students awarded top honors for research on bio-separation techniques

Three students from Rochester Institute of Technology were recognized for their research findings about improvements to bio-separation techniques for lab-on-a-chip medical devices. They were awarded top honors in several categories in the undergraduate and graduate research competitions at the American Institute of Chemical Engineers annual meeting and conference in November in Salt Lake City, Utah.

28 Jan 2016

Nutrition and breast cancer; starving triple negative breast cancer cells to death: an interview with Associate Professor Jeff Holst

While there are a range of reports that different foods and food groups can increase or decrease your risk of cancer, these associations are very difficult to scientifically verify.

27 Jan 2016

Technology leader award given to Leica Microsystems

Wetzlar, Germany. The research and consulting company Frost & Sullivan has recognized Leica Microsystems’ newly acquired Optical Coherence Tomography (OCT) company Bioptigen of Morrisville, North Carolina, USA, as a technology leader and pioneer of the North American ophthalmic imaging industry.

From Leica Microsystems GmbH 21 Jan 2016

IMP, WEHI scientists successfully characterize central regulator of plasma cell function

Plasma cells play a key role in our immune system. Now scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria, and at the Walter and Eliza Hall Institute (WEHI) in Melbourne, Australia, succeeded in characterizing a central regulator of plasma cell function.

20 Jan 2016

Animal antibodies help identify diseased cells during immunohistology procedures

We all know it from biology lessons at school: Antibodies help us to ward off disease and are essential components of our immune system. What many people do not know is that physicians and scientists use animal antibodies to identify diseased or mutated cells.

20 Jan 2016

UGA study helps solve mystery of how African trypanosomes communicate

While scientists have known for years that African trypanosomes cause sleeping sickness, they've been left scratching their heads as to how these tiny single-celled organisms communicate. A University of Georgia study, published Jan. 14 in the journal Cell, helps solve this mystery.

18 Jan 2016

Researchers reveal secondary structure of Lewy bodies in the brain of Parkinson's disease patients

Lewy bodies had been considered to be a key element of pathogenesis for Parkinson's disease. Although structural analysis for Lewy bodies with an electron microscope had been performed, it had no secondary structural information of proteins, which is important for the development of drugs.

13 Jan 2016

Mechanical properties of bone revealed through micro-indentation testing

Unravelling the mechanical properties of bone with micro-indentation testing has significance in both health and disease. At the University Medical Center Hamburg-Eppendorf, Dr. Björn Busse and his research group have advanced their micro-indentation testing technique using an Olympus industrial inspection digital light microscope, as an alternative to electron microscopy. The cutting edge research is described in a new application note from Olympus, available online.

From Evident Corporation - Life Sciences 12 Jan 2016

Cancer concerns over chromium diet pills

Concerns have been raised over the long-term use of nutritional supplements containing chromium, after an Australian research team found the supplement is partially converted into a carcinogenic form when it enters cells.

12 Jan 2016

Interpretation of images starts in the retina

Tübingen researchers have shown that image processing in the eye is more extensive than previously thought. They investigated the channels that transmit information from the eye to the brain.

7 Jan 2016

New injectable agent can potentially increase surgeon's ability to remove cancerous tumor during surgery

Doctors at the Duke University School of Medicine have tested a new injectable agent that causes cancer cells in a tumor to fluoresce, potentially increasing a surgeon's ability to locate and remove all of a cancerous tumor on the first attempt. The imaging technology was developed through collaboration with scientists at Duke, the Massachusetts Institute of Technology and Lumicell Inc.

7 Jan 2016

Lipoprotein nanoplatelets important for imaging biological molecules and cells

An interdisciplinary research team from the University of Illinois at Urbana-Champaign has developed a new material composite derived from quantum dots. These lipoprotein nanoplatelets are rapidly taken up by cells and retain their fluorescence, making them particularly well-suited for imaging cells and understanding disease mechanisms.

6 Jan 2016

Fraunhofer scientists use antibodies to detect cancer cells in tissue samples

Antibodies combat viruses and bacteria. They also attach themselves to cancer cells - in a typical, characteristic way. Fraunhofer scientists are using this property to detect cancer cells in tissue samples. Such rapid tests can already be applied by surgeons during operations - within a few minutes and without expensive equipment.

4 Jan 2016

3-D recordings of nematode brains may help understand how neurons coordinate action and perception

Princeton University researchers have captured among the first recordings of neural activity in nearly the entire brain of a free-moving animal. The three-dimensional recordings could provide scientists with a better understanding of how neurons coordinate action and perception in animals.

31 Dec 2015

New model provides images of single cell with micrometer resolution

Thermal properties of cells regulate their ability to store, transport or exchange heat with their environment. So gaining control of these properties is of great interest for optimizing cryopreservation -- the process of freezing and storing blood or tissues, which is also used when transporting organs for transplants.

30 Dec 2015

CMU researchers develop new method to survey learning-related changes in synapse properties

Carnegie Mellon University researchers have developed a new approach to broadly survey learning-related changes in synapse properties. In a study published in the Journal of Neuroscience and featured on the journal's cover, the researchers used machine-learning algorithms to analyze thousands of images from the cerebral cortex. This allowed them to identify synapses from an entire cortical region, revealing unanticipated information about how synaptic properties change during development and learning.

29 Dec 2015

Microscope News and Research

Multinational study suggests new way to classify gliomas

Researchers create new neuronal connections for the first time

Three Case Western faculty members receive funding to develop new diagnostic technologies

Study provides detailed new information about diffuse glioma

Three RIT students awarded top honors for research on bio-separation techniques

Nutrition and breast cancer; starving triple negative breast cancer cells to death: an interview with Associate Professor Jeff Holst

Technology leader award given to Leica Microsystems

IMP, WEHI scientists successfully characterize central regulator of plasma cell function

Animal antibodies help identify diseased cells during immunohistology procedures

UGA study helps solve mystery of how African trypanosomes communicate

Researchers reveal secondary structure of Lewy bodies in the brain of Parkinson's disease patients

Mechanical properties of bone revealed through micro-indentation testing

Cancer concerns over chromium diet pills

Interpretation of images starts in the retina

New injectable agent can potentially increase surgeon's ability to remove cancerous tumor during surgery

Lipoprotein nanoplatelets important for imaging biological molecules and cells

Fraunhofer scientists use antibodies to detect cancer cells in tissue samples

3-D recordings of nematode brains may help understand how neurons coordinate action and perception

New model provides images of single cell with micrometer resolution

CMU researchers develop new method to survey learning-related changes in synapse properties

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Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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