Pathogen News and Research

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Coronavirus deranges the immune system in complex and deadly ways

There's a reason soldiers go through basic training before heading into combat: Without careful instruction, green recruits armed with powerful weapons could be as dangerous to one another as to the enemy.

4 Mar 2021

Rapid point-of-care test used to diagnose respiratory infections can reduce antibiotic prescribing

A rapid microbiological point-of-care test to diagnose respiratory infections has proved popular with GPs and could reduce antibiotic prescribing in primary care, according to a National Institute for Health Research funded study by researchers at the Centre for Academic Primary Care, University of Bristol.

4 Mar 2021

Obesity may reduce COVID-19 vaccine efficacy, say researchers

A startling indicates that obesity may reduce the immune response to the current COVID-19 vaccines, along with other factors like age and sex. This could have significant implications for vaccination strategies in obese people.

3 Mar 2021

Novel SARS-CoV-2 spike vaccine candidate produces strong neutralizing response in vivo

A new study by researchers at Mahidol University in Bangkok, Thailand, reports a COVID-19 vaccine candidate called HexaPro in producing neutralizing antibodies against the SARS-CoV-2 spike protein in an animal model.

3 Mar 2021

New nanoparticle-delivered COVID-19 vaccine candidate shows efficacy in ferret model

Researchers from Cleveland Clinic's Global Center for Pathogen Research & Human Health have developed a promising new COVID-19 vaccine candidate that utilizes nanotechnology and has shown strong efficacy in preclinical disease models.

2 Mar 2021

Optimal storage protocols of wastewater samples for SARS-CoV-2 RNA detection

A new preprint released on the medRxiv* server by researchers at the University of Innsbruck, Austria, takes this further in order to establish the limits of storage procedures while working on viral surveillance in this area.

2 Mar 2021

Biological activity-based modeling offers a new approach for drug discovery

Assessing a drug compound by its activity, not simply its structure, is a new approach that could speed the search for COVID-19 therapies and reveal more potential therapies for other diseases.

2 Mar 2021

A backbone free energy study of SARS-CoV-2 variants of concern

A recent study by scientist Robert Penner at the Institut des Hautes Études Scientifiques in France utilizes free energy calculations to predict effective antiviral targets that are highly conserved, surface-accessible for interaction, and resistant to mutation.

1 Mar 2021

Could SARS-CoV-2 antibody tests before first vaccine dose help increase coverage and protection?

A new study by scientists in the UK raises the very useful hypothesis that natural infection may help spread the vaccine thinner without loss of efficacy.

1 Mar 2021

SARS-CoV-2 modulates host cell central carbon metabolism for reproduction

A team of scientists from Sweden and India has recently characterized the host cell metabolic alterations associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Their findings reveal that SARS-CoV-2 modulates the host cell's central carbon metabolism to facilitate replication and infection propagation.

28 Feb 2021

Study shows how D614G variant gains upper hand over original SARS-CoV-2 virus

Prior to the emergence of new mutants of the coronavirus, such as the British variant B.1.1.7, the SARS-CoV-2 variant named D614G had already mutated from the original SARS-CoV-2 pathogen that triggered the pandemic.

27 Feb 2021

Bacteria use slimy strategy to defeat antibiotics that fight cystic fibrosis

University of Montana researchers and their partners have discovered a slimy strategy used by bacteria to defeat antibiotics and other drugs used to combat infections afflicting people with cystic fibrosis. The research was published Feb. 23 in the journal Cell Reports.

27 Feb 2021

Study provides different characteristics of COVID-19

The Coronavirus Disease 2019 (COVID-19) pandemic has affected almost every part of the globe with millions of cases and over a million deaths.

27 Feb 2021

Structure of SARS-CoV-2 envelope protein-epithelial cell junction protein complex explains virulence

A new study by researchers at Brookhaven National Laboratory and Stony Brook University in the U.S. describes the key interaction between the viral envelope (E) protein and the human cell junction protein, PALS1. The latter is necessary to establish and maintain cell polarity and tight junctions between cells.

26 Feb 2021

What is the impact of demographics and air quality on COVID-19 mortality?

A new piece of research was conducted using a wide range of variables related to demographic and environmental factors in New York State (NYS), USA. NYS consists of urban and ethnically diverse counties, some of which are population-dense while others are population-sparse.

26 Feb 2021

Researchers use Doppler to look inside living cells, track their metabolic activity

Doppler radar improves lives by peeking inside air masses to predict the weather. A Purdue University team is using similar technology to look inside living cells, introducing a method to detect pathogens and treat infections in ways that scientists never have before.

26 Feb 2021

Study examines the future psyche of post-COVID-19 traveler

Our deep-rooted survival instinct for disease avoidance could make us less willing to embrace strangers and take foreign travel risks.

26 Feb 2021

Simple pooled testing method can be an effective tool for curbing COVID-19 pandemic

A new approach to pooled COVID-19 testing can be a highly effective tool for curbing the SARS-CoV-2 pandemic, even if infections are widespread in a community, according to researchers at Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard.

25 Feb 2021

Research shows how antibodies attach to and block Zika virus

The Zika outbreak of 2015 and 2016 are having lasting impacts on children whose mothers became infected with the virus while they were pregnant.

25 Feb 2021

Study addresses COVID-19 pandemic concerns and guidelines for increasing food safety

A team of researchers from the United States Department of Agriculture examined how the COVID-19 pandemic has changed food practices and safety protocols for workers in food-processing plants.

25 Feb 2021

Pathogen News and Research

Coronavirus deranges the immune system in complex and deadly ways

Rapid point-of-care test used to diagnose respiratory infections can reduce antibiotic prescribing

Obesity may reduce COVID-19 vaccine efficacy, say researchers

Novel SARS-CoV-2 spike vaccine candidate produces strong neutralizing response in vivo

New nanoparticle-delivered COVID-19 vaccine candidate shows efficacy in ferret model

Optimal storage protocols of wastewater samples for SARS-CoV-2 RNA detection

Biological activity-based modeling offers a new approach for drug discovery

A backbone free energy study of SARS-CoV-2 variants of concern

Could SARS-CoV-2 antibody tests before first vaccine dose help increase coverage and protection?

SARS-CoV-2 modulates host cell central carbon metabolism for reproduction

Study shows how D614G variant gains upper hand over original SARS-CoV-2 virus

Bacteria use slimy strategy to defeat antibiotics that fight cystic fibrosis

Study provides different characteristics of COVID-19

Structure of SARS-CoV-2 envelope protein-epithelial cell junction protein complex explains virulence

What is the impact of demographics and air quality on COVID-19 mortality?

Researchers use Doppler to look inside living cells, track their metabolic activity

Study examines the future psyche of post-COVID-19 traveler

Simple pooled testing method can be an effective tool for curbing COVID-19 pandemic

Research shows how antibodies attach to and block Zika virus

Study addresses COVID-19 pandemic concerns and guidelines for increasing food safety

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