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Study finds high rate of misuse of seizure and pain drug

With increasing public attention to overdose deaths and misuse of prescription medications in the United States, researchers today presented the results of a new study looking at abuse and misuse of gabapentin, a medication used to treat seizures and relieve nerve pain often associated with shingles.

3 Aug 2016

Researchers develop new hybrid method to study HIV protein involved in disease progression

More than 36 million people worldwide, including 1.2 million in the U.S., are living with an HIV infection. Today's anti-retroviral cocktails block how HIV replicates, matures and gets into uninfected cells, but they can't eradicate the virus.

3 Aug 2016

Scientists uncover genetic cause of rare pediatric progressive neuropathy

Researchers from the National Institutes of Health and their colleagues identified the genetic cause and a possible therapeutic target for a rare form of pediatric progressive neuropathy.

3 Aug 2016

People with filariasis show two to three-fold increased risk for HIV

Since the start of the HIV epidemic, there have been speculations as to why HIV and the immunodeficiency syndrome it causes have spread so much more in Africa than in other countries around the world.

3 Aug 2016

Study shows hospitals that send more number of heart patients to ICU perform worse in quality of care

Patients who suffer heart attacks, or flare-ups of congestive heart failure, can be cared for in a variety of hospital locations. But a new study suggests that they'll fare worse in hospitals that rely heavily on their intensive care units to care for patients like them.

3 Aug 2016

Neurologists identify cause of immune-mediated neuropathies

Würzburg neurologists have discovered an antibody that is involved in triggering certain forms of neuropathies. This discovery also allowed them to show a way to treat these diseases successfully.

3 Aug 2016

Research paves way for development of new drugs to prevent cancer and Alzheimer's

A new generation of drugs that prevent cancer and Alzheimer's could be developed, thanks to research from the University of Warwick.

3 Aug 2016

E. coli K1 inhibits glucose transporters during meningitis, report scientists

Escherichia coli K1 (E. coli K1) continues to be a major threat to the health of young infants. Affecting the central nervous system, it causes neonatal meningitis by multiplying in immune cells, such as macrophages, and then disseminating into the bloodstream to subsequently invade the blood-brain barrier.

3 Aug 2016

Scientists use new non-invasive PET scanning method to monitor hippocampal neurogenesis

Scientists from the RIKEN Center for Life Science Technology in Japan have used a new non-invasive PET scanning technique to obtain images of neuron proliferation in the subventricular zone and subgranular zone of the hippocampal dentate gyrus. Neurogenesis in the hippocampal dentate gyrus is known to be particularly affected by depression.

3 Aug 2016

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Cancer immunotherapy drugs that block the inhibitory PD-1 pathway have shown success in clinical trials and are now FDA-approved for melanoma, lung cancer and bladder cancer. Yet many patients' tumors do not respond to these drugs.

3 Aug 2016

New Valley Fever testing technology developed by TGen and NAU receives U.S. patent

Valley Fever, a potentially deadly dust-borne fungal disease, should be easier to diagnose and treat thanks to a testing technology developed by the Translational Genomics Research Institute and Northern Arizona University, and now protected by a patent issued today by the U.S. Patent and Trademark Office.

3 Aug 2016

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Reprogramming of the molecular pathways underlying normal metabolism is essential for T cell infection-fighting function and for the immune system to form a "memory" of the microbes it has already encountered. But exactly how metabolism in exhausted T cells is maintained in chronic infections and cancer is a missing element in this line of research.

3 Aug 2016

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Scientists have engineered a sort of biological barbell that can get inside cancer cells and do damage to two proteins that work independently and together to enable cancer's survival and spread.

3 Aug 2016

Advances in head and neck cancer treatments: an interview with Prof. Argiris

Patients with head and neck cancer usually present with locally advanced disease and often require more than one type of treatment, which may include surgery, radiotherapy, and chemotherapy.

3 Aug 2016

Research finding opens door to potential clinical approaches that may boost body's ability to battle cancer

The microenvironment that supports a cancerous tumor also starves the immune cells that the body sends in to destroy the cancer, University of Pittsburgh Cancer Institute scientists revealed in a discovery that holds the potential to significantly boost the performance of breakthrough immunotherapy drugs.

2 Aug 2016

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

UT Southwestern Medical Center researchers have found an important innate immunity role for a gene linked to a rare, fatal syndrome in children. Their study has implications for a much more common disease: tuberculosis.

2 Aug 2016

Griffith University to collaborate with Olymvax for new vaccine technology that could benefit millions

Griffith University will partner with a Chinese pharmaceutical, Olymvax Biopharmaceuticals Inc. for a new vaccine that could benefit millions.

2 Aug 2016

UTA researchers find how changing estrogen levels make women more vulnerable to cocaine addiction

Researchers at The University of Texas at Arlington are studying how fluctuating estrogen levels make females increasingly sensitive to the rewarding effects of cocaine and ultimately, vulnerable to cocaine addiction.

2 Aug 2016

New report reveals high levels of caffeine in energy drinks could lead to cardiac complications

The high levels of caffeine in energy drinks may lead to cardiac complications, suggests a case report in the July/August Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine. The journal is published by Wolters Kluwer.

2 Aug 2016

Scientists develop model using transformed stem cells to accelerate screening of drugs for rare cancers

Researchers at the Johns Hopkins Kimmel Cancer Center say they have developed a system that uses transformed human stem cells to speed up screening of existing drugs that might work against rare brain and other cancers.

2 Aug 2016

Drugs News and Research

Study finds high rate of misuse of seizure and pain drug

Researchers develop new hybrid method to study HIV protein involved in disease progression

Scientists uncover genetic cause of rare pediatric progressive neuropathy

People with filariasis show two to three-fold increased risk for HIV

Study shows hospitals that send more number of heart patients to ICU perform worse in quality of care

Neurologists identify cause of immune-mediated neuropathies

Research paves way for development of new drugs to prevent cancer and Alzheimer's

E. coli K1 inhibits glucose transporters during meningitis, report scientists

Scientists use new non-invasive PET scanning method to monitor hippocampal neurogenesis

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

New Valley Fever testing technology developed by TGen and NAU receives U.S. patent

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Advances in head and neck cancer treatments: an interview with Prof. Argiris

Research finding opens door to potential clinical approaches that may boost body's ability to battle cancer

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

Griffith University to collaborate with Olymvax for new vaccine technology that could benefit millions

UTA researchers find how changing estrogen levels make women more vulnerable to cocaine addiction

New report reveals high levels of caffeine in energy drinks could lead to cardiac complications

Scientists develop model using transformed stem cells to accelerate screening of drugs for rare cancers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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