Genetic News and Research

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Malfunction of brain architecture can prompt neuron to make 'early-career' switch

Scientists at the Salk Institute have discovered that the role of neurons -- which are responsible for specific tasks in the brain -- is much more flexible than previously believed.

12 May 2015

Leicester research team identifies potential new targets for cancer treatments

An international consortium of scientists led by a group from the University of Leicester has announced a new advance in understanding the mechanisms of cancer and how to target it more effectively with new treatments...

12 May 2015

Experimental gene therapy holds promise against metastatic prostate cancer

Even with the best available treatments, the median survival of patients with metastatic, hormone-refractory prostate cancer is only two to three years. Driven by the need for more effective therapies for these patients, researchers at VCU Massey Cancer Center and the VCU Institute of Molecular Medicine have developed a unique approach that uses microscopic gas bubbles to deliver directly to the cancer a viral gene therapy in combination with an experimental drug that targets a specific gene driving the cancer's growth.

12 May 2015

OSU scientists develop more accurate method to evaluate cancer risk of pollutants

Scientists at Oregon State University have developed a faster, more accurate method to assess cancer risk from certain common environmental pollutants.

12 May 2015

Study highlights potential new targets for development of novel cancer therapy

12 May 2015

Study sheds light on specific roles for dopamine in reward process

Dopamine is the chemical messenger in the brain most closely associated with pleasure and reward. Recent scientific advances now shed light on precise roles for dopamine in the reward process.

12 May 2015

Scientists identify gene that causes hereditary hypertension and brachydactyly type E

Individuals with this altered gene have hereditary hypertension (high blood pressure) and at the same time a skeletal malformation called brachydactyly type E, which is characterized by unusually short fingers and toes. The effect on blood pressure is so serious that -- if left untreated -- it most often leads to death before age fifty.

11 May 2015

Walnut-enriched diet may slow colorectal tumor growth

A new animal study from Beth Israel Deaconess Medical Center, Harvard Medical School, led by Dr. Christos Mantzoros, indicates that a diet containing walnuts may slow colorectal tumor growth by causing beneficial changes in cancer genes.

11 May 2015

MJFF announces acquisition of parkin research tools from Imago Pharmaceuticals

The Michael J. Fox Foundation for Parkinson's Research announces the acquisition of a library of research tools around the parkin protein from Imago Pharmaceuticals. The Foundation believes these tools — cell lines, plasmids, compounds and more — will accelerate biological study and drug development against this promising disease-modification target.

11 May 2015

Raising lupus awareness: an interview with Professor Ramsey-Goldman, MD

Lupus is a chronic, autoimmune disease, with many different symptoms so it is hard to diagnose. It affects each person differently and it has an unpredictable disease course with flare ups and quiet time. Some patients describe lupus as if they are riding a roller coaster with blinders on because they cannot always tell when they will feel well or sick...

11 May 2015

The future of cancer treatment set to be transformed through the opening of new Cancer Institute

NHS patients will soon benefit from the opening of a new cancer centre specialising in the use of diagnostics for targeted cancer medicines used to treat some of the UK’s most common cancers...

11 May 2015

Obesity rates elevated in childhood cancer survivors who are exposed to certain treatments

Individuals who had cancer as a child may be at increased risk of being obese due to the therapies they received during their youth. The finding comes from a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. The study's results suggest the need for effective counseling and weight loss interventions for certain childhood cancer survivors.

11 May 2015

Study finds link between PTSD and accelerated aging

In recent years, public health concerns about post-traumatic stress disorder (PTSD) have risen significantly, driven in part by affected military veterans returning from conflicts in the Middle East and elsewhere. PTSD is associated with number of psychological maladies, among them chronic depression, anger, insomnia, eating disorders and substance abuse.

10 May 2015

Study sheds light on developing more targeted therapies against medulloblastoma

St. Jude Children's Research Hospital scientists have gained ground toward developing more targeted therapies for the most common childhood brain tumor.

10 May 2015

Moffitt scientists examine why prostate cancer patients who receive ADT experience hot flashes

Androgen deprivation therapy (ADT) is a common treatment option for patients with advanced stage prostate cancer. But nearly 80 percent of patients who receive ADT report experiencing hot flashes during and after treatment. Moffitt Cancer Center researchers are working to determine what genetic factors and other characteristics might make prostate cancer patients more likely to experience hot flashes during and after therapy.

10 May 2015

Genes influence ADHD course

A large twin study shows that genetics have a major influence on whether attention deficit/hyperactivity disorder symptoms decrease or persist as children grow older.

8 May 2015

Scripps Florida scientists win $2.4 million to expand development of new pain therapies

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded $2.4 million from the National Institute on Drug Abuse of The National Institutes of Health to expand development of new pain medications with fewer side effects than those currently available...

8 May 2015

Gene expression is key to understanding differences between individuals and predisposition to disease

The Genotype-Tissue Expression (GTEx) project consortia, which includes scientists from the Centre for Genomic Regulation (CRG) in Barcelona, have now published their results from their first pilot study in three Science papers...

8 May 2015

Discovery opens up new avenue for development of potential therapies to treat, prevent malaria

Scientists have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite. This discovery opens up a promising new avenue for the development of therapies to treat and prevent malaria.

8 May 2015

Overexpression of cyclin E protein could lead to breast cancer, leukemia

A new study led by scientists at The Scripps Research Institute sheds light on the cause of some cancers, including breast cancer and leukemia.

8 May 2015

Genetic News and Research

Malfunction of brain architecture can prompt neuron to make 'early-career' switch

Leicester research team identifies potential new targets for cancer treatments

Experimental gene therapy holds promise against metastatic prostate cancer

OSU scientists develop more accurate method to evaluate cancer risk of pollutants

Study highlights potential new targets for development of novel cancer therapy

Study sheds light on specific roles for dopamine in reward process

Scientists identify gene that causes hereditary hypertension and brachydactyly type E

Walnut-enriched diet may slow colorectal tumor growth

MJFF announces acquisition of parkin research tools from Imago Pharmaceuticals

Raising lupus awareness: an interview with Professor Ramsey-Goldman, MD

The future of cancer treatment set to be transformed through the opening of new Cancer Institute

Obesity rates elevated in childhood cancer survivors who are exposed to certain treatments

Study finds link between PTSD and accelerated aging

Study sheds light on developing more targeted therapies against medulloblastoma

Moffitt scientists examine why prostate cancer patients who receive ADT experience hot flashes

Genes influence ADHD course

Scripps Florida scientists win $2.4 million to expand development of new pain therapies

Gene expression is key to understanding differences between individuals and predisposition to disease

Discovery opens up new avenue for development of potential therapies to treat, prevent malaria

Overexpression of cyclin E protein could lead to breast cancer, leukemia

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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