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Phase I study of selumetinib drug shows partial response in pediatric neural tumors

In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated selumetinib and, in most cases, responded to it with tumor shrinkage.

29 Dec 2016

ACHD Program at Cincinnati Children's to receive ACHA accreditation

The Adolescent and Adult Congenital Heart Disease (ACHD) Program at Cincinnati Children's Hospital Medical Center is one of a handful of programs in the nation to be awarded accreditation by the Adult Congenital Heart Association (ACHA).

29 Dec 2016

Article reports increase in health care spending on children

Health care spending on children grew 56 percent between 1996 and 2013, with the most money spent in 2013 on inpatient well-newborn care, attention deficit/hyperactivity disorder (ADHD) and well-dental care, according to an article published online by JAMA Pediatrics.

28 Dec 2016

Shooting consumer fireworks and drinking do not mix, cautions National Council on Fireworks Safety

New Year's Eve is a wonderful time to celebrate the start of a new year. And fireworks are a wonderful way of celebrating! However, all too often, New Year's Eve festivities involve excess alcohol.

28 Dec 2016

Study reports volume and cost of in-home care for children with special medical conditions

U.S. families provide nearly $36 billion annually in uncompensated medical care at home to children who have special health care needs, such as muscular dystrophy and cystic fibrosis, according to a large national study.

28 Dec 2016

Study highlights lack of nutritional standards for premixed infant cereals in lower-income countries

For parents around the world, premixed infant cereals--also known as complementary foods--can be a vital source of the solid food needed for healthy child growth after six months of age, when infants outgrow the nutrients provided by breast milk alone.

28 Dec 2016

Research highlights need to improve sleep for homeless people

The homeless sleep less and are more likely to have insomnia and daytime fatigue than people in the general population, findings researchers believe suggest more attention needs to be paid to improving sleep for this vulnerable population, according to a research letter published online by JAMA Internal Medicine.

28 Dec 2016

Study identifies new mechanism of how inhibitory brain cells develop

Scientists have discovered that networks of inhibitory brain cells or neurons develop through a mechanism opposite to the one followed by excitatory networks.

27 Dec 2016

Potential drug could become first effective treatment option for Prader-Willi syndrome

Duke Health researchers have identified a drug-like small molecule that, in animal experiments, appears to be an effective treatment for a genetic disorder called Prader-Willi syndrome.

27 Dec 2016

Study tracks parents' unpaid time assisting children with special health care needs

About half of U.S. children with special health care needs -- 5.6 million children -- receive medical care from uncompensated family members worth billions of dollars, finds a large national study led by Boston Children's Hospital and the University of Southern California (USC).

27 Dec 2016

Experimental drug improves survival, growth outcomes in mouse model of Prader-Willi syndrome

Drugs capable of activating silenced genes improve survival and growth outcomes in a mouse model of Prader-Willi syndrome, a rare and incurable childhood disease, according to a study funded by the National Institutes of Health.

27 Dec 2016

CSHL researcher-inventor hails FDA approval of new SMA drug

Within a week of Christmas day, a drug called nusinersen will be in the hands of doctors across the nation, who will use it, most urgently, to treat young children with a severe and potentially fatal illness called spinal muscular atrophy (SMA).

26 Dec 2016

New study shows efficacy of Ebola vaccine in offering protection against disease

An experimental Ebola vaccine was highly protective against the deadly virus in a major trial in Guinea, according to a new study that included researchers from the University of Maryland School of Medicine.

26 Dec 2016

Ionis announces FDA approval of first SMA drug in the U.S for pediatric and adult patients

Ionis Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration has approved SPINRAZATM (nusinersen) under Priority Review for the treatment of spinal muscular atrophy (SMA) in pediatric and adult patients.

26 Dec 2016

Experimental Ebola vaccine offers high protection against deadly virus, reveals major trial

An experimental Ebola vaccine was highly protective against the deadly virus in a major trial in Guinea, according to results published today in The Lancet. The vaccine is the first to prevent infection from one of the most lethal known pathogens, and the findings add weight to early trial results published last year.

23 Dec 2016

MDA celebrates FDA approval of new spinal muscular atrophy drug

The Muscular Dystrophy Association today celebrated news of the U.S. Food and Drug Administration's decision to grant approval for nusinersen (brand name Spinraza), the first disease-modifying drug to treat the most common genetic cause of death in infants.

23 Dec 2016

DDF launches three grants to fund opportunities for gastric cancer research

Debbie's Dream Foundation: Curing Stomach Cancer, an international non-profit organization that raises awareness and funds for stomach cancer, launched three research grants totaling $300,000 for the 2016-2017 grant cycle.

23 Dec 2016

Inherited CD70 deficiency increases susceptibility to Epstein-Barr virus and EBV-related cancer

Investigators at the National Institutes of Health and international colleagues have identified a genetic immune disorder characterized by increased susceptibility and poor immune control of Epstein-Barr virus (EBV) and, in some cases, an EBV-associated cancer called Hodgkin's lymphoma.

23 Dec 2016

FDA approves first drug to treat children and adults with spinal muscular atrophy

The U.S. Food and Drug Administration today approved Spinraza (nusinersen), the first drug approved to treat children and adults with spinal muscular atrophy (SMA), a rare and often fatal genetic disease affecting muscle strength and movement.

23 Dec 2016

Caregiving can have positive effect on mortality of carers, study shows

Older people who help and support others are also doing themselves a favor. An international research team has found that grandparents who care for their grandchildren on average live longer than grandparents who do not.

23 Dec 2016

Children News and Research

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

ACHD Program at Cincinnati Children's to receive ACHA accreditation

Article reports increase in health care spending on children

Shooting consumer fireworks and drinking do not mix, cautions National Council on Fireworks Safety

Study reports volume and cost of in-home care for children with special medical conditions

Study highlights lack of nutritional standards for premixed infant cereals in lower-income countries

Research highlights need to improve sleep for homeless people

Study identifies new mechanism of how inhibitory brain cells develop

Potential drug could become first effective treatment option for Prader-Willi syndrome

Study tracks parents' unpaid time assisting children with special health care needs

Experimental drug improves survival, growth outcomes in mouse model of Prader-Willi syndrome

CSHL researcher-inventor hails FDA approval of new SMA drug

New study shows efficacy of Ebola vaccine in offering protection against disease

Ionis announces FDA approval of first SMA drug in the U.S for pediatric and adult patients

Experimental Ebola vaccine offers high protection against deadly virus, reveals major trial

MDA celebrates FDA approval of new spinal muscular atrophy drug

DDF launches three grants to fund opportunities for gastric cancer research

Inherited CD70 deficiency increases susceptibility to Epstein-Barr virus and EBV-related cancer

FDA approves first drug to treat children and adults with spinal muscular atrophy

Caregiving can have positive effect on mortality of carers, study shows

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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