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Scientists trace one of the causes of ischemia renal failure

Every year acute renal failure affects over 13 million people and leads to 1.7 million deaths across the globe. It often develops when an insufficient supply of oxygen reaches the kidneys, a condition called ischemia.

29 Jan 2016

New blood clotting analysis system could help determine effects antithrombotic (anti-clotting) drugs

A new blood clotting analysis system designed in Japan makes it easier to determine the effects of taking one or more antithrombotic (anti-clotting) drugs.

29 Jan 2016

Zepatier receives FDA approval for treatment of chronic HCV genotypes 1 and 4 infections

The U.S. Food and Drug Administration today approved Zepatier (elbasvir and grazoprevir) with or without ribavirin for the treatment of chronic hepatitis C virus (HCV) genotypes 1 and 4 infections in adult patients.

29 Jan 2016

AbbVie announces initiation of first Elagolix Phase 3 study in patients with uterine fibroid

AbbVie, in cooperation with Neurocrine Biosciences, Inc., today announced the initiation of the first of two planned Phase 3 clinical studies evaluating the safety and efficacy of Elagolix alone or in combination with add-back therapy compared to placebo.

29 Jan 2016

Colorectal cancer in younger patients associated with more advanced disease but better survival

Nearly 15 percent of patients diagnosed with colorectal cancer were younger than 50, the age at which screening recommendations begin.

25 Jan 2016

New €5.6 million project aims to develop cell-based haemophilia A therapy

Loughborough University is working with a team of international partners on a new €5.6 million project to develop a cell based haemophilia A therapy.

25 Jan 2016

Gene therapy holds considerable potential for safe, effective treatment of people with factor VII deficiency

Hematology researchers have used a single injection of gene therapy to correct a rare bleeding disorder, factor VII deficiency, in dogs. This success in large animals holds considerable potential for a safe, effective and long-lasting new treatment in humans with the same bleeding disorder.

21 Jan 2016

Novel gene therapy treatment proves safe, effective for factor VII deficiency

A single injection. That's all someone with a factor VII deficiency would need for a life-long cure, thanks to a new gene therapy treatment developed in a collaboration of researchers at the University of North Carolina and The Children's Hospital of Philadelphia.

20 Jan 2016

New study finds efficacy of novel intravenous blood thinner in women

Percutaneous coronary intervention (PCI) is a staple of modern day medicine in which cardiologists place a stent in a blood vessel around the heart in order to restore blood flow in people with heart disease. Blood thinners allow for the procedure to be completed with a reduced risk of certain complications such as clots.

18 Jan 2016

Standardized treatment approach makes outpatient thyroid surgery a safe option for elderly patients

A standardized treatment approach that starts with good screening and ends with patients going home to well-prepared caregivers, means outpatient thyroid surgery is safe for the vast majority of patients, including the elderly and super-elderly, physician-scientists say.

13 Jan 2016

Middle-aged patients undergoing AVR may fare better with tissue-based valves rather than metal-based valves

Patients between the ages of 40 and 70 who undergo aortic valve replacement (AVR) may fare better with tissue-based valves rather than metal-based valves, according to a review article posted online today by The Annals of Thoracic Surgery.

13 Jan 2016

3 out of 4 young adults with stroke symptoms delay trip to hospital

Up to three hours after a person experiences the first symptom of a stroke is often referred to as the "golden window." That's the period of time doctors say is crucial for patients to get to a hospital to receive medical care in order to restore blood flow to the brain and minimize or reverse damage.

11 Jan 2016

Wyss Institute scientists develop better assay for testing hemostasis

Scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University have devised a better assay for testing blood's clotting tendency, also known as hemostasis, which could one day prove lifesaving in a variety of clinical situations in which a patient's health is jeopardized by abnormal blood coagulation and platelet function.

11 Jan 2016

Drug-microbe interactions may contribute to adverse effects, lessen effectiveness of NSAID

A nonsteroidal anti-inflammatory drug (NSAID) changed the composition and diversity of gut microbes, which in turn shaped how the drug is broken down and ultimately, cut its effectiveness, according to an animal study from the Perelman School of Medicine at the University of Pennsylvania.

5 Jan 2016

FDA issues two final orders to strengthen requirements for transvaginal surgical mesh safety

The U.S. Food and Drug Administration today issued two final orders to manufacturers and the public to strengthen the data requirements for surgical mesh to repair pelvic organ prolapse (POP) transvaginally, or through the vagina.

5 Jan 2016

MUSC researchers receive PCORI grant to study safety, effectiveness of three blood-thinning drugs

A research team at the Medical University of South Carolina has been approved for a $13.5 million funding award by the Patient-Centered Outcomes Research Institute to study the safety and effectiveness of three blood-thinning drugs used to prevent potentially deadly blood clots in patients undergoing hip and knee replacement.

5 Jan 2016

Concussion expert shares important information on sports-related concussions

The Sports Concussion Program in the Children's Orthopaedic Center at Children's Hospital Los Angeles is the only pediatric program of its kind in Southern California.

26 Dec 2015

YAP protein appears to play vital role in helping control inflammation inside the brain

Inside the brain, a protein called YAP, best known for its ability to help right-size our developing hearts and livers, appears to have the different but equally important task of helping control inflammation.

23 Dec 2015

Penn study explores bleeding complications linked to cardiac stent placement techniques

More than 375,000 American each year experience a heart attack, during which blood flow to a part of the heart is impeded by blocked arteries. Physicians often treat patients with stents, which prop open the arteries to allow blood to flow again. They use two approaches to place stents: transradial, or entry of the catheter which delivers the stent through the wrist, or transfemoral, in which the catheter is placed through the groin.

23 Dec 2015

New $8.5M research grant aims to address patients affected by severe hemophilia A

People with hemophilia have prolonged abnormal bleeding as a result of trauma. Hemophilia A, also called factor VIII (FVIII) deficiency, is the most common form of the genetic disorder caused by missing or defective blood clotting protein called factor VIII.

23 Dec 2015

Bleeding News and Research

Scientists trace one of the causes of ischemia renal failure

New blood clotting analysis system could help determine effects antithrombotic (anti-clotting) drugs

Zepatier receives FDA approval for treatment of chronic HCV genotypes 1 and 4 infections

AbbVie announces initiation of first Elagolix Phase 3 study in patients with uterine fibroid

Colorectal cancer in younger patients associated with more advanced disease but better survival

New €5.6 million project aims to develop cell-based haemophilia A therapy

Gene therapy holds considerable potential for safe, effective treatment of people with factor VII deficiency

Novel gene therapy treatment proves safe, effective for factor VII deficiency

New study finds efficacy of novel intravenous blood thinner in women

Standardized treatment approach makes outpatient thyroid surgery a safe option for elderly patients

Middle-aged patients undergoing AVR may fare better with tissue-based valves rather than metal-based valves

3 out of 4 young adults with stroke symptoms delay trip to hospital

Wyss Institute scientists develop better assay for testing hemostasis

Drug-microbe interactions may contribute to adverse effects, lessen effectiveness of NSAID

FDA issues two final orders to strengthen requirements for transvaginal surgical mesh safety

MUSC researchers receive PCORI grant to study safety, effectiveness of three blood-thinning drugs

Concussion expert shares important information on sports-related concussions

YAP protein appears to play vital role in helping control inflammation inside the brain

Penn study explores bleeding complications linked to cardiac stent placement techniques

New $8.5M research grant aims to address patients affected by severe hemophilia A

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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