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Mouse protein disrupts cancer-causing epigenetic changes in human colorectal cancer

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new study from researchers at the Johns Hopkins Kimmel Cancer Center and the Chinese Academy of Sciences.

16 Jan 2025

T-DM1 reduces long-term risk of death in HER2-positive breast cancer patients

In patients with high-risk HER2-positive breast cancer, post-surgery, or adjuvant, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive disease by 46% and improved survival compared to trastuzumab alone, according to the final results of the phase 3 KATHERINE clinical trial led by researchers from the University of Pittsburgh and UPMC Hillman Cancer Center.

16 Jan 2025

Xenon gas offers potential neuroprotective effects for Alzheimer's patients

Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research from Mass General Brigham and Washington University School of Medicine in St. Louis points to a novel-and noble-approach: using Xenon gas.

16 Jan 2025

Pheno Therapeutics receives clinical trial authorization for novel multiple sclerosis therapeutic

Pheno Therapeutics Limited., a biotechnology company focused on the discovery and development of small molecule therapeutics for the treatment of neurological diseases, announced today it has received clinical trial authorization (CTA) from the UK’s MHRA (Medicines and Healthcare products Regulatory Agency) for its lead candidate, PTD802.

15 Jan 2025

Sapio Sciences introduces new tools for chemistry, molecular biology, GMP workflows, and immunogenicity

Sapio Sciences, the science-aware™ lab informatics platform, today announced the launch of Release 24.12, introducing new tools for chemistry, molecular biology, GMP workflows, and immunogenicity.

15 Jan 2025

Eating greater quantities of red meat may increase risk of dementia

Red meat consumption is an established risk factor for chronic conditions, including cardiovascular disease and type 2 diabetes.

15 Jan 2025

New target identified for potential colorectal cancer treatment

Colorectal cancer (CRC) is a type of cancer that begins in the colon (large intestine) or rectum, which are parts of the digestive system.

15 Jan 2025

Scientists unveil global patterns in early-life gut microbial evolution

Scientists reveal that early-life gut microbiome development follows universal patterns, paving the way for new benchmarks in child health assessments.

15 Jan 2025

Study reveals how cigarette smoke weakens immune cells in the lungs

Cigarette smoking is widespread and deadly, yet our understanding of how cigarette smoke actually causes serious respiratory illnesses is incomplete, which has severely hampered the development of effective treatments.

15 Jan 2025

PIN1 protein found to be a significant driver of bladder cancer

Like all cancers, bladder cancer develops when abnormal cells start to multiply out of control. But what if we could put a lid on their growth?

15 Jan 2025

Mayo Clinic partners with Microsoft Research and Cerebras to revolutionize AI in healthcare

Mayo Clinic today unveiled separate groundbreaking collaborations with Microsoft Research and with Cerebras Systems in the field of generative artificial intelligence (AI), designed to personalize patient care, significantly accelerate diagnostic time and improve accuracy.

15 Jan 2025

Researchers identify a natural defense against blood vessel inflammation and atherosclerosis

Research reveals IGFBP6's role in suppressing vascular inflammation and atherosclerosis, suggesting it as a novel target for cardiovascular disease therapy.

15 Jan 2025

Scientists discover how specific protein regions contribute to breast cancer

Researchers at Case Western Reserve University School of Medicine have discovered how specific protein regions contribute to breast cancer.

15 Jan 2025

New compounds show promise in treating retinitis pigmentosa

Two new compounds may be able to treat retinitis pigmentosa, a group of inherited eye diseases that cause blindness.

15 Jan 2025

Study highlights benefits of pork consumption for older adults in South Korea

New research underscores the potential role of pork consumption in supporting dietary and muscle health in Korean older adults.

15 Jan 2025

Spear Bio secures FDA breakthrough device designation for its novel pTau 217 blood test, advancing scalable solutions for early Alzheimer's disease diagnosis

Spear Bio Inc., a biotechnology company pioneering next-generation ultra-sensitive immunoassays, today announced that its pTau 217 blood test has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration (FDA).

From Spear Bio 15 Jan 2025