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Rett Syndrome, the first identified epigenetic disease - linked to specific defects in the three-dimensional folding of chromatin

Sometime between the age of 6 and 18 months, after a period of seemingly normal development, girls affected with Rett Syndrome lose interest in play; they gradually become withdrawn and anxious, develop autistic-like behaviors, and acquire specific symptoms like repetitive teeth-grinding and hand-wringing.

20 Dec 2004

Ethical challenges ahead for neuroscience and society

Are we ready for a future where brain scans invade our private thoughts? Will we have to alter our brains chemically to keep competitive at our jobs? Could science determine that "souls" do not exist, and, if so, what does that mean for how we think of ourselves as human beings?

20 Dec 2004

Discovery of new compound known as SP-4-84 could lead to improved chemotherapy treatments

The discovery of a new compound by Michigan State University researchers could lead to improved chemotherapy treatments for different types of cancers – potentially with fewer side effects.

20 Dec 2004

Risk of tuberculosis infection doubles within one year of HIV infection

Scientists previously assumed that there was no increase in tuberculosis risk within the first few years of HIV infection. Pam Sonnenberg of the London School of Hygiene and Tropical Medicine and colleagues were therefore surprised by the results of their research on the two infections, which they conducted in South African gold miners.

20 Dec 2004

Wine, fish, dark chocolate, fruits and vegetables cut the risk of heart disease

Scientists in this week's Christmas issue of the BMJ have discovered the 'Polymeal', a set of ingredients which cuts the risk of heart (cardiovascular) disease by 76% and significantly increases life expectancy.

20 Dec 2004

Genealogy in a cancer prevention curriculum for high school students

A team of researchers from Virginia Commonwealth University are using an old tool to teach new information about cancer: the family tree.

19 Dec 2004

Low-dose diuretic therapy for most patients with hypertension recommended

Patients with high blood pressure who take calcium channel blockers and diuretics have an increased risk for cardiovascular disease (CVD) death compared to patients who take beta-blockers plus diuretics, according to a study in the current issue of JAMA.

16 Dec 2004

Study models impact of anthrax vaccine

Rapidly distributing antibiotics to people exposed to anthrax spores during a bioterrorist attack, could by itself, prevent about 70 percent of anthrax infections from occurring, according to researchers from the Johns Hopkins Bloomberg School of Public Health.

16 Dec 2004

Key advance in understanding the proteins and mechanisms involved in the spread of Lyme Disease

Virginia Commonwealth University scientists have made a key advance in understanding the proteins and mechanisms involved in the spread of Lyme Disease, a finding that could lead to a vaccine against the tick-borne illness that affects thousands of people each year.

16 Dec 2004

Millennium Pharmaceuticals discovers protein biomarkers that could play a role in the early detection of rheumatoid arthritis

Researchers at Millennium Pharmaceuticals today announced the discovery of a panel of protein biomarkers that could play a role in the early detection, prognosis and monitoring of rheumatoid arthritis (RA).

14 Dec 2004

New theory driving evolutionary changes

Researchers at UT Southwestern Medical Center at Dallas have used canine DNA to identify a genetic mutation mechanism they believe is responsible for rapid evolutionary changes in the physical appearance of many species.

14 Dec 2004

Cardiac and non-cardiac deaths peak during Christmas and New Year’s in part because people delay seeking medical treatment

Cardiac and non-cardiac deaths peak during Christmas and New Year’s in part because people delay seeking medical treatment, researchers report in today’s Circulation: Journal of the American Heart Association.

14 Dec 2004

Scientists have identified a novel anti-tuberculosis (TB) compound

Scientists at Johnson & Johnson Pharmaceutical Research and Development have identified a novel anti-tuberculosis (TB) compound that works better and faster than the current standard of care in mouse models of TB infection.

14 Dec 2004

Revised safety advice on chromium picolinate supplements

The Food Standards Agency has revised its advice on the safety of chromium picolinate supplements. It is no longer advising people to avoid this type of chromium.

14 Dec 2004

Vaccinating mice against Lyme disease could help reduce the risk of transmission of the disease to humans

Vaccinating large populations of white-footed mice against the bacterium that causes Lyme disease could help reduce the risk of transmission of the disease to humans, says a study supported by the National Institute of Allergy and Infectious Diseases (NIAID).

14 Dec 2004

M.E. emerges from the wilderness

In 1955 medical literature first defined and described M.E., an illness that had probably been with us for hundreds of years. But with a wide range of symptoms, no diagnostic test and much misunderstanding about its cause, people with M.E. often had to struggle to manage the illness with little support from specialist services.

14 Dec 2004

Landmark studies that may change the treatment standards for breast cancer

The 27th Annual San Antonio Breast Cancer Symposium that took place December 8-11 included the presentation of several landmark studies that may change the treatment standards for breast cancer.

14 Dec 2004

Safety of AIDS drug to prevent mother-to-child transmission of HIV questioned

In light of several recent drug industry scandals roiling the nation's public health and raising serious questions about the US bodies that license and regulate the industry -- and startling new revelations today concerning National Institutes of Health (NIH) officials and the safety of a brand name AIDS drug used to prevent mother-to-child transmission of the HIV

14 Dec 2004

False positive cancer screening tests result not only in anxiety but also additional economic costs

Cancer screening tests can frequently produce false positive outcomes that may result not only in anxiety but also additional economic costs as well, according to research conducted by scientists at the Henry Ford Health System, Detroit, Mich., and published in the December issue of Cancer Epidemiology, Biomarkers & Prevention

14 Dec 2004

Men seem to stop trying when they remarry

Men seem to stop trying when they remarry, suggests research in the Journal of Epidemiology and Community Health. They put on weight and cut down on exercise.

13 Dec 2004

Research News and Research

Rett Syndrome, the first identified epigenetic disease - linked to specific defects in the three-dimensional folding of chromatin

Ethical challenges ahead for neuroscience and society

Discovery of new compound known as SP-4-84 could lead to improved chemotherapy treatments

Risk of tuberculosis infection doubles within one year of HIV infection

Wine, fish, dark chocolate, fruits and vegetables cut the risk of heart disease

Genealogy in a cancer prevention curriculum for high school students

Low-dose diuretic therapy for most patients with hypertension recommended

Study models impact of anthrax vaccine

Key advance in understanding the proteins and mechanisms involved in the spread of Lyme Disease

Millennium Pharmaceuticals discovers protein biomarkers that could play a role in the early detection of rheumatoid arthritis

New theory driving evolutionary changes

Cardiac and non-cardiac deaths peak during Christmas and New Year’s in part because people delay seeking medical treatment

Scientists have identified a novel anti-tuberculosis (TB) compound

Revised safety advice on chromium picolinate supplements

Vaccinating mice against Lyme disease could help reduce the risk of transmission of the disease to humans

M.E. emerges from the wilderness

Landmark studies that may change the treatment standards for breast cancer

Safety of AIDS drug to prevent mother-to-child transmission of HIV questioned

False positive cancer screening tests result not only in anxiety but also additional economic costs

Men seem to stop trying when they remarry

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