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Soy-based drug could prevent prostate cancer metastasis

Northwestern Medicine researchers at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University have found that a new, nontoxic drug made from a chemical in soy could prevent the movement of cancer cells from the prostate to the rest of the body.

8 Nov 2010

New findings could help scientists devise optimal therapies for Friedreich's ataxia

Scripps Research Institute scientists have taken a step closer to understanding the cause of Friedreich's ataxia, a debilitating neurological condition that affects tens of thousands of people worldwide, and so far has no cure.

8 Nov 2010

Scientists identify genes that enable some immune systems to halt HIV; finding could spur drug, vaccine development

Tiny variants in a protein that alerts the body to infection could explain how one in 300 HIV-infected people are able to resist the onset of AIDS for years without needing any treatment, researchers said Thursday in a study published online in the journal Science, Agence France-Presse reports

8 Nov 2010

Prolonged separation from mother increases risk of breast cancer in young mice

Young mice that experienced the psychosocial stress of prolonged separation from their mothers had a higher incidence and faster onset of breast tumors compared with young mice who did not experience this stressful life event. Specifically, neonatal mice separated from their mothers for a prolonged period of time developed mammary tumors twice as fast as mice that experienced short or no maternal separation.

8 Nov 2010

Deletion of 17q12 chromosomal region increases risk factor for ASD, schizophrenia

Researchers have identified the deletion of a genomic region on chromosome 17 as a significant risk factor for autism spectrum disorders (ASD) and schizophrenia. A mutation of one of the genes in the deleted interval already is a known cause of renal cysts and diabetes syndrome (RCAD).

8 Nov 2010

Researchers identify gene linked to melanoma metastasis

Researchers at Washington University School of Medicine in St. Louis have identified a gene linked to the spread of eye melanoma.

8 Nov 2010

Sudden epilepsy death explained

Sudden unexpected death in epilepsy (SUDEP) is a condition that kills about 150 Australians a year. Now researchers have discovered the reasons behind such deaths. The study was conducted by scientists at the Centenary Institute at the University of Sydney who looked at blood samples taken from epilepsy suffers who had died suddenly and found that there were genetic faults in the heart and brain.

7 Nov 2010

First Edition: November 4, 2010

Less than 24 hours after Republicans won control of the House, soon-to-be-speaker John Boehner denounced the new health care law, saying it would "kill jobs in America, ruin the best health care system in the world, and bankrupt our country" -- and renewed his vow to try to repeal it. Kaiser Health News asked people around the country to answer the following question: "If you ended up in an elevator with Rep. Boehner, what single thing would you urge him to do about health care in this country? (Kaiser Health News).

4 Nov 2010

Agilent announces solution for exon analysis based on SurePrint G3 Exon Microarrays

Agilent Technologies Inc. today announced a solution for exon analysis based on SurePrint G3 Exon Microarrays. The solution provides a major expansion of Agilent's portfolio of gene expression reagents, microarrays and bioinformatics systems. This new system, available in mid-November, enables researchers to examine alternately expressed exons according to recently updated content, providing a global picture of RNA expression.

4 Nov 2010

Pfizer's two new compounds may be effective in treating alcohol, nicotine dependence

Researchers at the Ernest Gallo Clinic and Research Center at the University of California, San Francisco, and Pfizer Inc., have determined that two new compounds may be effective in treating both alcohol and nicotine dependence at the same time.

4 Nov 2010

New findings on mitochondrial haplogroups associated with successful aging to be presented at ASHG Meeting

Thousands of the world's top scientists and clinicians in the human genetics field will convene to present their latest research findings at the American Society of Human Genetics (ASHG) 60th Annual Meeting, on November 2-6, 2010, in Washington, D.C.

4 Nov 2010

Beginner's guide to cancer

An academic from The University of Nottingham has written the first introductory guide to cancer, covering everything from the biology of the disease and why some people are more at risk of developing it than others, to the latest research into prevention, treatment and cure.

4 Nov 2010

Gene fusion prostate cancers susceptible to secondary mutations

Scientists at Weill Cornell Medical College have taken an important step toward a better understanding of prostate cancer by uncovering evidence that it is not one disease, as previously believed, but rather several factors which can be measured and, in the future, destroyed by targeted therapy.

4 Nov 2010

Scientists discover gene variant that rewires brain's circuitry in neurological disorders

Many gene variants have been linked to autism, but how do these subtle changes alter the brain, and ultimately, behavior. Using a blend of brain imaging and genetic detective work, scientists at UCLA's David Geffen School of Medicine and Semel Institute for Neuroscience and Human Behavior are the first to illustrate how a gene variant tied to autism rewires the brain.

4 Nov 2010

New simple blood test may help diagnose Niemann-Pick type C disease

A fatal genetic disorder that frequently takes years to diagnose may soon be detectable with a simple blood test, researchers at Washington University School of Medicine in St. Louis and the National Institutes of Health (NIH) report this week in Simple blood test may diagnose deadly Niemann-Pick type C disease.

4 Nov 2010

Alnylam third quarter revenue increases from $24.2 million to $27.7 million

Alnylam Pharmaceuticals, Inc. a leading RNAi therapeutics company, today reported its consolidated financial results for the third quarter ended September 30, 2010, and company highlights.

4 Nov 2010

Bortezomib reduces inflammation and promotes bone healing in arthritis models

A new study by Greek researchers suggests that the biologic drug bortezomib (Velcade), a proteasome inhibitor used to treat multiple myeloma (bone marrow cancer), may represent a promising treatment for rheumatoid arthritis (RA). In this study, bortezomib displayed favorable effects in an animal model of inflammatory arthritis that mimics RA, in reducing disease severity and inflammation, and promoting bone healing. Full findings of this study are published in the November issue of Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR).

3 Nov 2010

Ingenuity Systems and Geospiza partner to enable seamless next-generation sequencing analysis workflow

Ingenuity® Systems, a leading provider of information solutions for life science researchers, and Geospiza, Inc., the market leading developer of laboratory management and genetic analysis software, today announced a collaboration to enable a seamless next-generation sequencing analysis workflow. The companies will integrate their software products, GeneSifter® and IPA®, to enable researchers to obtain deep biological insights from their project samples through a rapid and reliable workflow to analyze and visualize next-generation sequencing data.

3 Nov 2010

Allen Institute releases new data and tools for exploring genes at work in human brain

The Allen Institute for Brain Science announced today its twentieth public data release, which includes new data and tools for exploring genes at work in the human brain. In addition to expanding and enhancing the Allen Human Brain Atlas, the Allen Institute launched two new human brain resources: the Ivy Glioblastoma Atlas Project and the NIMH Transcriptional Atlas of Human Brain Development.

3 Nov 2010

LVI in breast tissue predicts recurrence of breast cancer in regional lymph nodes

Breast cancer, one of the most prevalent cancers in women, afflicts an additional 200,000 women each year and causes about 40,000 deaths annually. The disease often extends to neighboring lymph nodes, in part, through lymphovascular invasion (LVI)-a process in which cancer cells invade blood vessels or the lymphatic system-and can often translate into a poor prognosis for patients.

3 Nov 2010

Genes News and Research

Soy-based drug could prevent prostate cancer metastasis

New findings could help scientists devise optimal therapies for Friedreich's ataxia

Scientists identify genes that enable some immune systems to halt HIV; finding could spur drug, vaccine development

Prolonged separation from mother increases risk of breast cancer in young mice

Deletion of 17q12 chromosomal region increases risk factor for ASD, schizophrenia

Researchers identify gene linked to melanoma metastasis

Sudden epilepsy death explained

First Edition: November 4, 2010

Agilent announces solution for exon analysis based on SurePrint G3 Exon Microarrays

Pfizer's two new compounds may be effective in treating alcohol, nicotine dependence

New findings on mitochondrial haplogroups associated with successful aging to be presented at ASHG Meeting

Beginner's guide to cancer

Gene fusion prostate cancers susceptible to secondary mutations

Scientists discover gene variant that rewires brain's circuitry in neurological disorders

New simple blood test may help diagnose Niemann-Pick type C disease

Alnylam third quarter revenue increases from $24.2 million to $27.7 million

Bortezomib reduces inflammation and promotes bone healing in arthritis models

Ingenuity Systems and Geospiza partner to enable seamless next-generation sequencing analysis workflow

Allen Institute releases new data and tools for exploring genes at work in human brain

LVI in breast tissue predicts recurrence of breast cancer in regional lymph nodes

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