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Blocking gene's activity may control deadly skin cancer without harming normal cells

Researchers at Dana-Farber Cancer Institute and Children's Hospital Boston have discovered that malignant melanoma, the potentially lethal skin cancer, can't grow without a steady supply of a protein that normal cells can do without.

20 Dec 2004

Blocking a key molecule protects breast implants, permanent catheters, pacemakers and artificial joints from rejection and damage by the body

Blocking a key molecule protects breast implants, permanent catheters, pacemakers, artificial joints, glucose sensors for diabetics, and other biomaterials from rejection and damage by the body, according to a study published this month in The American Journal of Pathology.

20 Dec 2004

Cherries could help lower blood sugar levels in people with diabetes

Perhaps George Washington wouldn't have chopped down his father's cherry tree if he knew what chemists now know. They have identified a group of naturally occurring chemicals abundant in cherries that could help lower blood sugar levels in people with diabetes.

20 Dec 2004

DLX5 gene may play a role in the pathology of Rett Syndrome

A research team led by Terumi Kohwi-Shigematsu of the Life Sciences Division of Lawrence Berkeley National Laboratory has identified a gene, DLX5, that may play a role in the pathology of Rett Syndrome, a devastating neurological disorder diagnosed almost exclusively in girls.

20 Dec 2004

Timing of radiation and antiangiogenic therapy impacts treatment effectiveness

Agents designed to attack blood vessels that feed a growing tumor are effective against tumor growth in laboratory experiments. However, results of early clinical trials with these inhibitors have not yet exhibited the same success observed in animal models.

20 Dec 2004

Messenger RNA not only are measurable in saliva but can indicate a developing tumor

Scientists funded by the National Institute of Dental and Craniofacial Research reported today taking a major step forward in using saliva to detect oral cancer.

20 Dec 2004

Stem cells use inflammatory signals to find injured tissue

A joint effort led by stem cell biologist Evan Y. Snyder, M.D., Ph.D., of The Burnham Institute, and Samia J. Khoury, M.D., of Harvard Medical School and Brigham and Women’s Hospital, report data suggesting that stem cells use inflammatory signals to “know” where they must home.

20 Dec 2004

Researchers discover clues to cirrhosis

Researchers at the University of Essex have found new biochemical indicators of cirrhosis in blood plasma which could help detect the disease in its early stages.

20 Dec 2004

Vaccine against cervical cancer

Dutch researcher Laura Bungener has developed a vaccine against cervical cancer. Vaccinated laboratory animals no longer developed the disease and animals which had already developed a tumour, could be treated with the vaccine.

20 Dec 2004

Macugen approved for the treatment of neovascular (wet) age-related macular degeneration (AMD)

Eyetech Pharmaceuticals and Pfizer have announced that the U.S. Food and Drug Administration (FDA) approved Macugen (pegaptanib sodium injection) for the treatment of neovascular (wet) age-related macular degeneration (AMD), an eye disease associated with aging that destroys central vision.

20 Dec 2004

Rett Syndrome, the first identified epigenetic disease - linked to specific defects in the three-dimensional folding of chromatin

Sometime between the age of 6 and 18 months, after a period of seemingly normal development, girls affected with Rett Syndrome lose interest in play; they gradually become withdrawn and anxious, develop autistic-like behaviors, and acquire specific symptoms like repetitive teeth-grinding and hand-wringing.

20 Dec 2004

10 to 20 million people in the United States have chronic kidney disease but most don’t know it

10 to 20 million people in the United States have chronic kidney disease but most don’t know it, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health, the National Institute of Diabetes and Digestive and Kidney Diseases and the National Center for Health Statistics.

19 Dec 2004

New clue to nerve growth may help regeneration efforts

Johns Hopkins scientists have discovered how one family of proteins repels growing nerves and keeps them properly on track during development.

16 Dec 2004

Key advance in understanding the proteins and mechanisms involved in the spread of Lyme Disease

Virginia Commonwealth University scientists have made a key advance in understanding the proteins and mechanisms involved in the spread of Lyme Disease, a finding that could lead to a vaccine against the tick-borne illness that affects thousands of people each year.

16 Dec 2004

Millennium Pharmaceuticals discovers protein biomarkers that could play a role in the early detection of rheumatoid arthritis

Researchers at Millennium Pharmaceuticals today announced the discovery of a panel of protein biomarkers that could play a role in the early detection, prognosis and monitoring of rheumatoid arthritis (RA).

14 Dec 2004

Vaccinating mice against Lyme disease could help reduce the risk of transmission of the disease to humans

Vaccinating large populations of white-footed mice against the bacterium that causes Lyme disease could help reduce the risk of transmission of the disease to humans, says a study supported by the National Institute of Allergy and Infectious Diseases (NIAID).

14 Dec 2004

Instead of chemotherapy, drugs that influence the X protein's behavior might become an alternative cancer therapy

Identifying the link between chronic hepatitis B infection and liver cancer may one day help cancer patients sidestep the poison of chemotherapy, a Purdue University study suggests.

13 Dec 2004

Start today of human tests for a preventive vaccine against the respiratory disease SARS

Powerful research tools that speed up vaccine development have led to the start today of human tests for a preventive vaccine against the respiratory disease SARS. The disease killed hundreds of people around the world before it was brought under control in 2003 with aggressive conventional public health measures.

13 Dec 2004

Celebrex like gene suppresses the growth of colon cancer

Cancer researchers at the Case Western Reserve University (Case) School of Medicine, University Hospitals of Cleveland (UHC) and the Howard Hughes Medical Institute have found a "Celebrex-like" gene that suppresses the growth of colon cancer.

13 Dec 2004

Wiping out a protein in skin cancer cells could significantly stall melanoma tumor development

The protein, Akt3, appears to be responsible for promoting tumor cell survival and development in 43 percent to 60 percent of non-inherited melanomas.

13 Dec 2004

G Protein News and Research

Blocking gene's activity may control deadly skin cancer without harming normal cells

Blocking a key molecule protects breast implants, permanent catheters, pacemakers and artificial joints from rejection and damage by the body

Cherries could help lower blood sugar levels in people with diabetes

DLX5 gene may play a role in the pathology of Rett Syndrome

Timing of radiation and antiangiogenic therapy impacts treatment effectiveness

Messenger RNA not only are measurable in saliva but can indicate a developing tumor

Stem cells use inflammatory signals to find injured tissue

Researchers discover clues to cirrhosis

Vaccine against cervical cancer

Macugen approved for the treatment of neovascular (wet) age-related macular degeneration (AMD)

Rett Syndrome, the first identified epigenetic disease - linked to specific defects in the three-dimensional folding of chromatin

10 to 20 million people in the United States have chronic kidney disease but most don’t know it

New clue to nerve growth may help regeneration efforts

Key advance in understanding the proteins and mechanisms involved in the spread of Lyme Disease

Millennium Pharmaceuticals discovers protein biomarkers that could play a role in the early detection of rheumatoid arthritis

Vaccinating mice against Lyme disease could help reduce the risk of transmission of the disease to humans

Instead of chemotherapy, drugs that influence the X protein's behavior might become an alternative cancer therapy

Start today of human tests for a preventive vaccine against the respiratory disease SARS

Celebrex like gene suppresses the growth of colon cancer

Wiping out a protein in skin cancer cells could significantly stall melanoma tumor development

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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