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Synageva announces submission of Kanuma application to Cofepris for treatment of LAL Deficiency

Synageva BioPharma Corp., a biopharmaceutical company developing therapeutic products for rare disorders, announced today the submission to the Comisión Federal para la Protección contra Riesgos Sanitarios in Mexico for Kanuma as a treatment for patients with lysosomal acid lipase deficiency (LAL Deficiency), a rare genetic disease with significant morbidity and early mortality.

30 Mar 2015

Maternal diet during pregnancy and lactation may influence weight gain in offspring

Maternal diet during pregnancy and lactation may prime offspring for weight gain and obesity later in life, according to Penn State College of Medicine researchers, who looked at rats whose mothers consumed a high-fat diet and found that the offspring's feeding controls and feelings of fullness did not function normally.

30 Mar 2015

Fujifilm enters into definitive agreement to acquire Cellular Dynamics International

FUJIFILM Holdings Corporation (President: Shigehiro Nakajima) and Cellular Dynamics International, Inc. (CEO: Robert J. Palay), a leading developer and manufacturer of fully functioning human cells in industrial quantities to precise specifications, today announced that the two companies have entered into a definitive agreement whereby Fujifilm will acquire CDI via an all-cash tender offer to be followed by a second step merger.

30 Mar 2015

New study opens door to preventative treatments for congenital diaphragmatic hernia

Congenital diaphragmatic hernia (CDH) is not as well known as muscular dystrophy and cystic fibrosis, but like them it is a life-threatening birth defect, and is just as common. Occurring in one in 3,000 births, CDH causes the guts and liver to protrude through a defective diaphragm and into the chest cavity, where they interfere with the lungs.

30 Mar 2015

MDC scientists find solution to increase efficiency of precise genetic modifications

CRISPR-Cas9 is a powerful new tool for editing the genome. For researchers around the world, the CRISPR-Cas9 technique is an exciting innovation because it is faster and cheaper than previous methods. Now, using a molecular trick, Dr. Van Trung Chu and Professor Klaus Rajewsky of the Max Delbrück Center for Molecular Medicine Berlin-Buch and Dr. Ralf Kühn, MDC and Berlin Institute of Health, have found a solution to considerably increase the efficiency of precise genetic modifications by up to eightfold.

30 Mar 2015

Rare genetic mutation explains why flu can kill in rare cases

Nobody likes getting the flu, but for some people, fluids and rest aren't enough. A small number of children who catch the influenza virus fall so ill they end up in the hospital — perhaps needing ventilators to breathe — even while their family and friends recover easily. New research by Rockefeller University scientists, published March 26 in Science, helps explain why: a rare genetic mutation.

30 Mar 2015

Genes crucial for vision multiplied in early stages of vertebrate evolution

A new study from SciLifeLab at Uppsala University published in PLOS ONE shows that genes crucial for vision were multiplied in the early stages of vertebrate evolution and acquired distinct functions leading to the sophisticated mechanisms of vertebrate eyes.

30 Mar 2015

Queen's University Belfast, NCI partners to provide 4 year PhD programme in Precision Cancer Medicine

Queen's University Belfast is leading a major new international initiative into modern cancer care medicine which was announced today in Washington D.C.

30 Mar 2015

Iron oxide nanoparticles selectively target cell surface markers in tumor microenvironments

Nanoparticles hold great promise for cancer diagnostics and therapies, but only to the extent that they can be selectively guided to tumors and cancer cells.

30 Mar 2015

Researchers harness gene editing technique in mosquito that infects people with deadly diseases

Traditionally, to understand how a gene functions, a scientist would breed an organism that lacks that gene - "knocking it out" - then ask how the organism has changed. Are its senses affected? Its behavior?

30 Mar 2015

Research: Common bacteria poised to become antibiotic-resistant superbugs

Antibiotic resistance is poised to spread globally among bacteria frequently implicated in respiratory and urinary infections in hospital settings, according to new research at Washington University School of Medicine in St. Louis.

30 Mar 2015

Discovery opens new drug development avenues for treating multiple diseases

Researchers at the University of California, San Diego School of Medicine have discovered a control switch for the unfolded protein response (UPR), a cellular stress relief mechanism drawing major scientific interest because of its role in cancer, diabetes, inflammatory disorders and several neural degenerative disorders, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS), otherwise known as Lou Gehrig's disease.

30 Mar 2015

Study: Blood test may help diagnose Fragile X syndrome related disorders in women

A blood test may shed new light on Fragile X syndrome related disorders in women, according to a new study published in the March 25, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. Fragile X is the most common inherited form of intellectual disability and the most frequent genetic cause of autism.

30 Mar 2015

Women face Lymphangioleiomyomatosis risk during their childbearing years

A rare and potentially deadly lung disease called Lymphangioleiomyomatosis (LAM) strikes women during their childbearing years.

29 Mar 2015

Moffitt researchers use integrative approaches to study cancer heterogeneity

Moffitt Cancer Center researchers are using integrative approaches to study cancer by combining mathematical and computational modeling with experimental and clinical data. The use of integrative approaches enables scientists to study and model cancer progression in a manner that conventional experimental systems are unable to do.

29 Mar 2015

Public volunteers to highlight their role in improving care for patients at Sheffield Consumers in Research event

RESEARCH-active members of the public are to showcase how their vital work helps shape clinical research projects and improves care for patients at a free drop-in event in Sheffield City Centre on Wednesday 22 April.

27 Mar 2015

Stopping cellular quality-control mechanism can make chemotherapy more effective

A University of Rochester team found a way to make chemotherapy more effective, by stopping a cellular quality-control mechanism, according to a study published today in Nature Communications.

27 Mar 2015

Radiation resistance in leukemia can be overcome by using new precision medicine, say researchers

A team of researchers led by Fatih M. Uckun, MD, PhD, of The Saban Research Institute of Children's Hospital Los Angeles and Professor at the University of Southern California Keck School of Medicine has determined that radiation resistance in leukemia can be overcome by using an engineered protein they recently designed and developed as a new precision medicine against leukemia.

27 Mar 2015

Updated guidelines for diagnosis, treatment of medullary thyroid carcinoma released

A Task Force convened by the American Thyroid Association released updated guidelines for the diagnosis and treatment of medullary thyroid carcinoma (MTC). The current document is the first revision of the original guidelines published in 2009.

26 Mar 2015

Novo Nordisk announces U.S. launch of Novoeight for people living with hemophilia A

Novo Nordisk today announced the company will launch Novoeight (Antihemophilic Factor [Recombinant]) in the United States for people living with hemophilia A.

From Novo Nordisk 26 Mar 2015

Genetic News and Research

Synageva announces submission of Kanuma application to Cofepris for treatment of LAL Deficiency

Maternal diet during pregnancy and lactation may influence weight gain in offspring

Fujifilm enters into definitive agreement to acquire Cellular Dynamics International

New study opens door to preventative treatments for congenital diaphragmatic hernia

MDC scientists find solution to increase efficiency of precise genetic modifications

Rare genetic mutation explains why flu can kill in rare cases

Genes crucial for vision multiplied in early stages of vertebrate evolution

Queen's University Belfast, NCI partners to provide 4 year PhD programme in Precision Cancer Medicine

Iron oxide nanoparticles selectively target cell surface markers in tumor microenvironments

Researchers harness gene editing technique in mosquito that infects people with deadly diseases

Research: Common bacteria poised to become antibiotic-resistant superbugs

Discovery opens new drug development avenues for treating multiple diseases

Study: Blood test may help diagnose Fragile X syndrome related disorders in women

Women face Lymphangioleiomyomatosis risk during their childbearing years

Moffitt researchers use integrative approaches to study cancer heterogeneity

Public volunteers to highlight their role in improving care for patients at Sheffield Consumers in Research event

Stopping cellular quality-control mechanism can make chemotherapy more effective

Radiation resistance in leukemia can be overcome by using new precision medicine, say researchers

Updated guidelines for diagnosis, treatment of medullary thyroid carcinoma released

Novo Nordisk announces U.S. launch of Novoeight for people living with hemophilia A

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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