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Novel agent shown to have dual mechanism of action to eliminate cancer

Results from a study spearhead by researchers at the Vall d´Hebron Institute of Oncology (VHIO), show that the blockade of the multi-functional cytokine LIF induces tumor-infiltrating T Cells to hone in on and eliminate cancer.

11 Jun 2019

Researchers succeed in conquering chronic infection with hepatitis B virus

Researchers at Helmholtz Zentrum München and the Technical University of Munich, working in collaboration with researchers at the University Medical Center Hamburg-Eppendorf and the University Hospital Heidelberg, have for the first time succeeded in conquering a chronic infection with the hepatitis B virus in a mouse model.

11 Jun 2019

Plant-derived siRNAs could bring a 'green revolution' in RNAi tools and therapeutics

"Green revolution" in the early 1950s, the extensive cultivation of Dwarf Rice solves the food problem in developing countries. At present, chronic infection with hepatitis B virus (HBV) has been a major public health problem.

11 Jun 2019

Complex molecular conversation is key to the establishment of 'hot tumor'

A Ludwig Cancer Research study has deciphered a complex molecular conversation between cancer and immune cells that is key to orchestrating the successful invasion of tumors by T cells that kill cancer cells.

11 Jun 2019

AI technique helps produce high quality CT images at lower dosages

A team of bioengineers at Rensselaer Polytechnic Institute, with funding from the National Institute of Biomedical Imaging and Bioengineering, have developed an artificial intelligence technique that uses image post-processing to rapidly convert low-dose computed tomography scans to images of superior quality, compared to low-dose scans that do not use the AI technique.

11 Jun 2019

Children with T1D have slower growth in brain areas linked with mild cognitive deficits

A study co-led by Dr. Nelly Mauras at Nemours Children's Health System in Jacksonville, Florida found that children with type 1 diabetes have slower growth in brain areas associated with mild cognitive deficits compared to children without T1D.

11 Jun 2019

Emergency department overcrowding not linked to delayed hospitalization or death in children

Visiting a crowded pediatric emergency department in Canada may increase the likelihood of being hospitalized but is not linked to delayed hospitalization or death in children, according to research in CMAJ.

11 Jun 2019

Doctors urge hospitals to reconsider the type of fluids used to treat children with sepsis

Doctors have urged hospitals around the world to reconsider the type of fluids used to treat children gravely ill with sepsis.

11 Jun 2019

Radiation associated with increased risk of adverse cardiac events in lung cancer patients

As advances in the treatment of non-small cell lung cancer (NSCLC) extend patients' lives, more of these patients are facing a different threat: adverse cardiovascular events, such as heart attacks and heart failure.

11 Jun 2019

Discovery may lead to the development of early warning system for seizures

A new study has found a pattern of molecules that appear in the blood before a seizure happens. This discovery may lead to the development of an early warning system, which would enable people with epilepsy to know when they are at risk of having a seizure.

10 Jun 2019

Promising methods for early detection and treatment of rheumatoid arthritis

Rheumatoid arthritis is a chronic inflammatory autoimmune disorder that leads to significant health issues as well as high treatment costs. In this themed issue of Clinical Therapeutics, published by Elsevier, experts review multiple aspects of RA detection and intervention with the overall goal of moving the field closer to developing effective preventive measures.

10 Jun 2019

How measles detectives work to contain an outbreak

On any given day, more than 4,000 people pass through the library at California State University-Los Angeles.

10 Jun 2019

Mini-biographies help clinicians connect with patients

Bob Hall was recovering from yet another surgery in March 2014 when a volunteer walked into his hospital room. It had been a rocky recovery since his lung transplant three months earlier at the William S. Middleton Memorial Veterans Hospital in Madison, Wis.

10 Jun 2019

Novel radiotracer can identify nearly 30 types of malignant tumors

A novel class of radiopharmaceuticals has proven effective in non-invasively identifying nearly 30 types of malignant tumors, according to research published in the June issue of The Journal of Nuclear Medicine.

10 Jun 2019

World’s first clinical guidance on anal sex after prostate cancer treatments

UK doctors and surgeons have formulated what is probably the world's first clinical guidance on anal sex before, during, and after diagnosis and treatment for prostate cancer.

10 Jun 2019

AI tool can aid in the diagnosis of brain aneurysms

Doctors could soon get some help from an artificial intelligence tool when diagnosing brain aneurysms - bulges in blood vessels in the brain that can leak or burst open, potentially leading to stroke, brain damage or death.

8 Jun 2019

Sleep-disordered breathing severity associated with epigenetic age acceleration

Increasing severity of sleep-disordered breathing and sleep disruption are associated with epigenetic age acceleration, according to preliminary results of a new study.

8 Jun 2019

NIH awards $23 million grant to study the diseases affecting people with HIV

The National Institutes of Health has awarded a seven-year, $23 million grant to researchers at Albert Einstein College of Medicine and Montefiore Health System to study HIV and the chronic illnesses that often accompany HIV infection, including cardiovascular and lung disease, diabetes, and cancer.

8 Jun 2019