Cell Nucleus News and Research

RSS

Molecular pathway may contribute to age related diseases

A common molecular denominator in aging and many age-related diseases is oxidative stress.

1 Jun 2006

Bipolar disorder causes children to misinterpret facial expressions

Researchers at the National Institute of Mental Health (NIMH) have discovered why children with bipolar disorder tend to be more aggressive and irritable and have poorer social skills than healthy children.

31 May 2006

Scientists map the entire active protein inventory in cells

Scientists have shown how cutting-edge methods can be used to catalogue the entire inventory of active proteins in cell organelles at a particular moment. Their work sheds considerable light on how cells use proteins.

29 May 2006

Body has more than one body clock

Research conducted at Oregon Health & Science University suggests that contrary to popular belief, the body has more than one "body clock."

23 May 2006

In vivo, in vitro, in silico

Prof. Jens Reich, Biomathematician and member of the German National Ethics Council, is one of the scientists within the Systems Biology competence network HepatoSys who is on the scent of a major mystery of life.

17 May 2006

Plasminogen activator inhibitor type 2 may play role in infection and dry eye

Plasminogen Activator Inhibitor Type 2 (PAI-2), a protein found in various cell types including the skin, has been discovered in the tissue covering the eye and may have future clinical implications in various pathologies of the ocular surface such as eye infection or dry eye.

17 May 2006

Effective gene suppression using small interfering RNA in hard-to-transfect human T cells

A technical advance in laboratory techniques may provide biology researchers broader access to RNA interference, a process of blocking the activity of targeted genes. RNA interference has recently emerged as an important tool in studying how genes function in normal biological processes and in disease.

9 May 2006

Gene silencing protein discovered

A team of researchers, including biologists at Washington University in St. Louis, has discovered the key role one protein plays in a major turn-off -in this case, the turning off of thousands of nearly identical genes in a hybrid plant.

8 May 2006

Novel protein JHDM2A offers new look at male hormone regulation

For the second time in less than a year, University of North Carolina at Chapel Hill scientists have purified a novel protein and have shown it can alter gene activity by reversing a molecular modification previously thought permanent.

8 May 2006

Important insights into how cells regulate certain growth-proteins

Researchers here have discovered a new mechanism used by cells - and manipulated by retroviruses - to control the making of certain essential proteins, including some involved in cancer.

8 May 2006

An engineered virus that tracks down and compels cancer cells to eat themselves

An engineered virus tracks down and infects the most common and deadly form of brain cancer and then kills tumor cells by forcing them to devour themselves, researchers at The University of Texas M. D. Anderson Cancer Center report.

3 May 2006

DNA taxi

Despite few successes to date, gene therapy is a highly promising approach for medical therapy in the future.

1 May 2006

Researchers figure out how nuclear pores duplicate before cells divide

Researchers have long wondered how nuclear pores - the all-important channels that control the flow of information in and out of a cell's nucleus - double in number to prepare for the split to come when a cell divides. Now, for the first time, scientists at the Salk Institute for Biological Studies watched as new funnel-like pore structures formed from scratch, and inserted themselves into the nuclear membrane.

28 Apr 2006

Researchers develop system for observing nuclear motion

The cell is understood to be highly organized, with specialized areas for different functions and molecular motors shuttling components around.

18 Apr 2006

Stress-induced, high levels of corticotropin-releasing factor might be responsible for binge behaviour and addiction

Stressed individuals might be particularly prone to binge eating or drug addiction because of the high levels of the stress hormone corticotropin-releasing factor in their brain.

13 Apr 2006

Caudal raphe or the hypoglossal nucleus or both together play roles in sleep apnea

The neural pathways between two areas of the brain that control the tongue -- and their interactions with each other -- may hold the key as to why men suffer sleep apnea much more than women.

4 Apr 2006

Omega-3 fatty acids inhibit the growth of liver cancer cells

Two new studies by a University of Pittsburgh research team suggest that omega-3 fatty acids - substances that are found in high concentrations in fish oils and certain seeds and nuts - significantly inhibit the growth of liver cancer cells.

3 Apr 2006

Tobacco plants being used to produce human albumin

Human serum albumin (HSA) is the intravenous protein most commonly used in the world for therapeutic ends. It is employed to stabilise blood volume and to avoid risk of a heart attack, its administration in operating theatres being almost a daily occurrence.

27 Mar 2006

Researchers find potential new mechanism for how the brain's reward system works

Amid reports that a drug used to treat Parkinson's disease has caused some patients to become addicted to gambling and sex, University of Pittsburgh researchers have published a study that sheds light on what may have gone wrong.

23 Mar 2006