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Chemotherapy-induced amenorrhea improves survival in premenopausal women with early stage breast cancer

Chemotherapy-induced amenorrhea in premenopausal women being treated for early stage breast cancer was associated with significantly improved patient survival, according to a study published this week in the New England Journal of Medicine by the National Surgical Adjuvant Breast and Bowel Project (NSABP) in collaboration with leading US cancer centers and cooperative cancer research groups.

4 Jun 2010

Brain's cardiovascular, hormonal and asymmetric activation response when we get angry: UV scientists

When we get angry, the heart rate, arterial tension and testosterone production increases, cortisol (the stress hormone) decreases, and the left hemisphere of the brain becomes more stimulated. This is indicated by a new investigation lead by scientists from the University of Valencia that analyses the changes in the brain's cardiovascular, hormonal and asymmetric activation response when we get angry.

31 May 2010

Exposure in womb to BPA, DES increase offspring's risk of breast cancer

Exposure in the womb to chemicals like Bisphenol-A (BPA) and Diethylstilbestrol (DES) can increase an offspring's risk of breast cancer, researchers at Yale School of Medicine report in a study published in current issue of Hormones and Cancer, a journal of The Endocrine Society.

29 May 2010

Aggressive treatment of anaplastic thyroid carcinoma increases survival: Study

Aggressive treatment of anaplastic thyroid carcinoma has dramatically increased survival in the small group of patients who chose to undergo it, say physicians at Mayo Clinic. Their findings will be presented at the annual meeting of the American Society of Clinical Oncology, to be held June 4-8 in Chicago.

28 May 2010

Women with recurrent miscarriages can have successful pregnancy with supportive care

For women who have multiple miscarriages, the pain of repeated loss is often compounded by another reality. The causes behind miscarriage are complex and often difficult to identify, and even those conditions and associations proposed as causes are poorly understood.

28 May 2010

Study measures effects of BPA on male reproductive system

Increasing Bisphenol-A levels in urine are associated with worsening male sexual function, according to a Kaiser Permanente study appearing online in the Journal of Andrology.

28 May 2010

Highlights from June 2010 issue of American Journal of Pathology

Dr. Kanneboyina Nagaraju and colleagues at the Children's National Medical Center, Washington, DC demonstrate that affected muscle may directly contribute to inflammation in muscular dystrophy. Their report can be found in the June 2010 issue of The American Journal of Pathology.

26 May 2010

Researchers describe carcinogenic effects of EDCs

Longtime environmental health researchers at Tufts University School of Medicine describe the carcinogenic effects of endocrine-disrupting chemicals, ubiquitous chemicals that have hormone-like effects in the body. In a review article published online May 25 in Nature Reviews Endocrinology, the researchers express the need for more complex strategies for studying how these chemicals affect health but report that ample evidence already supports changing public health and environmental policies to protect the public from exposure to EDCs.

26 May 2010

Bristol-Myers Squibb announces positive results from Phase 2 study of ipilimumab in patients with NSCLC

Bristol-Myers Squibb Company today announced positive results from a randomized Phase 2 study evaluating ipilimumab in combination with standard chemotherapy in previously untreated patients with advanced non-small cell lung cancer.

21 May 2010

Women exposed prenatally to BPA or DES at increased risk of breast cancer: Study

A study in mice reveals that prenatal exposure to endocrine-disrupting chemicals, like bisphenol-A and diethylstilbestrol, may program a fetus for life. Therefore, adult women who were exposed prenatally to BPA or DES could be at increased risk of breast cancer, according to a new study accepted for publication in Hormones & Cancer, a journal of The Endocrine Society.

21 May 2010

Zebrafish may help scientists reveal function of mysterious enzyme linked to steroid cortisol

Michael E. Baker, PhD, a researcher at the University of California, San Diego School of Medicine has discovered that zebrafish - an important animal model in disease and environmental studies - could provide the means to help scientists eventually reveal the function of a mysterious enzyme linked to the steroid cortisol, and found in the human brain.

20 May 2010

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

Researchers from the Kimmel Cancer Center at Jefferson have found that Stat5, a signaling protein previously found to be key to survival of prostate cancer, is also involved in metastasis.

20 May 2010

i3 completes acquisition of ChinaGate

i3, a global life sciences services company and subsidiary of Ingenix, has acquired ChinaGate, a contract research organization that provides product-development regulatory services for pharmaceutical, medical device and biotechnology companies looking to enter and access the Chinese market.

19 May 2010

Choir singing induces state of stimulated regeneration in IBS patients

A Swedish investigation has compared choir singing and group discussion in irritable bowel syndrome in the current issue of Psychotherapy and Psychosomatics.

19 May 2010

President's Cancer Panel recommends home filtering devices to decrease exposure to cancer-causing agents

In its official annual report, the President's Cancer Panel is recommending that people use home filtering devices to decrease exposure to cancer-causing agents.

18 May 2010

Research sheds light on early embryogenesis, genetic disease

Chromosome 22q11 deletion syndrome (also known as DiGeorge syndrome) is the most common human chromosome deletion syndrome, having an estimated incidence of at least one in 4,000 live births.

15 May 2010

Research sheds light on prenatal heart formation, chromosome 22q.11 deletion syndrome

Researchers studying the common genetic disorder chromosome 22q.11 deletion syndrome have identified key proteins that act together to regulate early embryonic development. One protein is essential to life; in animal studies, embryos without the protein do not survive past the first few days of gestation.

13 May 2010

FDA approves Aeterna Zentaris' AEZS-108 IND for bladder cancer

Aeterna Zentaris Inc., a late-stage drug development company specialized in oncology and endocrine therapy, today announced that the U.S. Food and Drug Administration (FDA) has approved the Company's Investigational New Drug (IND) application for its doxorubicin targeted conjugate compound, AEZS-108, in luteinizing hormone releasing hormone (LHRH) receptor positive urothelial (bladder) cancer.

12 May 2010

Personalized treatments for thyroid disorders to be presented at ATA meeting

Internationally recognized thyroid disease experts will meet to discuss "Thyroid Disorders in the Era of Personalized Medicine" May 13 - 16 in Minneapolis, Minnesota at the American Thyroid Association's (ATA) (www.thyroid.org) Spring Meeting to be held at the Minneapolis Hyatt Regency Hotel.

11 May 2010

BIOTX introduces Estrofil menopause supplements in North America

BIOTX Limited – a manufacturer and developer of dietary supplements based on Traditional Chinese Medicine, today launched Estrofil in North America - an all-natural nutritional menopause supplement for the relief of menopausal symptoms. This new menopause natural remedy is not estrogen or hormone replacement therapy.

10 May 2010

Endocrine News and Research

Chemotherapy-induced amenorrhea improves survival in premenopausal women with early stage breast cancer

Brain's cardiovascular, hormonal and asymmetric activation response when we get angry: UV scientists

Exposure in womb to BPA, DES increase offspring's risk of breast cancer

Aggressive treatment of anaplastic thyroid carcinoma increases survival: Study

Women with recurrent miscarriages can have successful pregnancy with supportive care

Study measures effects of BPA on male reproductive system

Highlights from June 2010 issue of American Journal of Pathology

Researchers describe carcinogenic effects of EDCs

Bristol-Myers Squibb announces positive results from Phase 2 study of ipilimumab in patients with NSCLC

Women exposed prenatally to BPA or DES at increased risk of breast cancer: Study

Zebrafish may help scientists reveal function of mysterious enzyme linked to steroid cortisol

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

i3 completes acquisition of ChinaGate

Choir singing induces state of stimulated regeneration in IBS patients

President's Cancer Panel recommends home filtering devices to decrease exposure to cancer-causing agents

Research sheds light on early embryogenesis, genetic disease

Research sheds light on prenatal heart formation, chromosome 22q.11 deletion syndrome

FDA approves Aeterna Zentaris' AEZS-108 IND for bladder cancer

Personalized treatments for thyroid disorders to be presented at ATA meeting

BIOTX introduces Estrofil menopause supplements in North America

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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