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Chronic liver disease in COVID-19 patients

A recent study summarizes the clinical outcomes of COVID-19 patients with chronic liver disease.

10 Oct 2022

Scientists explore kinetics of naturally induced anti-SARS-CoV-2 antibodies in the Kenyan population

In a new study, researchers investigated the breadth and longevity of immunity induced by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure among the Kenyan population.

10 Oct 2022

Silver nanoparticle and polyurethane composite provides potential coating options to limit fomite transmission of SARS-CoV-2

In a new study, researchers synthesized and evaluated a silver and polyurethane nanocomposite surface coating material that exhibits antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

7 Oct 2022

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

Researchers demonstrated that the SARS-CoV-2 protein functions as a histone mimic to disrupt the epigenetic regulation of host cells.

7 Oct 2022

Study evaluates efficacy of a candidate SARS-CoV-2 subunit vaccine to protect endangered black-footed-ferrets

In a new study, researchers assessed the safety, efficacy, and immunogenicity of a candidate SARS-CoV-2 subunit vaccine in black-footed ferrets (BFF), and investigated the susceptibility of these endangered North American mammals to the virus.

7 Oct 2022

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Researchers established a neonatal mice model that enabled SARS-CoV-2 transmission.

7 Oct 2022

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

Researchers examined the replicative capacity of seven SARS-CoV-2 isolates in 17 cell lines to understand their phenotypic variations and host range.

7 Oct 2022

Study suggests an immunological benefit of combining previous natural infection with vaccination against COVID-19 using a combination of different vaccine platforms

Researchers explored SARS-CoV-2-targeted immune responses among COVAC1 participants who received a novel saRNA vaccine followed by the mRNA BNT162b2 vaccine BNT162b2 vaccine, with or without prior COVID-19 history.

7 Oct 2022

Researchers identify a new gene implicated in rare lysosomal storage disorder

In a rare disease called mucolipidosis type II, people’s hearts and abdomens swell, and their bones grow malformed.

6 Oct 2022

$The immune responses and safety of fractional third-doses of heterologous COVID-19 vaccines after CoronaVac primary series$

The immune responses and safety of fractional third-doses of heterologous COVID-19 vaccines after CoronaVac primary series

Researchers evaluated the vaccine effectiveness of half-doses of AZD1222 or BNT162b2 COVID-19 vaccines as a booster dose following primary series vaccination with CoronaVac.

6 Oct 2022

Stanford researchers create new technique for controlling protein production

Thanks to new RNA vaccines, we humans have been able to protect ourselves incredibly quickly from new viruses like SARS-CoV-2, the virus that causes COVID-19.

5 Oct 2022

Researchers uncover an intriguing previously unknown ability of Swiss army knife enzyme

Blue-green algae (AKA cyanobacteria) have a superpower which likely helps them be highly successful as invaders of waterways.

5 Oct 2022

Study opens avenues to improve prognosis of children with congenital hypogonadotropic hypogonadism

Congenital hypogonadotropic hypogonadism is a rare disease characterized by delayed puberty or the complete absence of puberty in adolescence, leading to infertility.

5 Oct 2022

Study shows the important role of hepatocyte adenosine kinase in NAFLD progression

A study led by Texas A&M AgriLife Research provides compelling evidence of the important role of hepatocyte adenosine kinase in the progression of nonalcoholic fatty liver disease, NAFLD.

5 Oct 2022

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

In a new study, researchers developed a three-dimensional (3D) in vitro tissue model to assess the effects of SARS-CoV-2 on the vascular endothelial cells.

5 Oct 2022

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Researchers engineered biparatopic nanobodies against SARS-CoV-2.

5 Oct 2022

Novel protein vaccine NVX-CoV2373 triggered functional T cell responses to SARS-CoV-2

Researchers determined the T cell response to the NVX-CoV2373, an adjuvanted recombinant full-length SARS-CoV-2 spike (S) trimer protein vaccine.

5 Oct 2022

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

In a new study, researchers determined the 1.8-Å resolution crystal structure of the H1 dual specific phosphatase (DSP) of monkeypox virus (MPXV) that is crucial for viral replication, making it an attractive antiviral target.

5 Oct 2022

Study shows SARS-CoV-2 infects human adipose tissue and undergoes productive infection in fat cells

Researchers demonstrated infection of human adipose tissue by SARS-CoV-2.

5 Oct 2022

Omicron reduces host antibody response by lower B-cell antigenicity

A new study explores the functional relevance of some Omicron mutations in terms of their ability to escape neutralizing antibody responses.

4 Oct 2022

Enzyme News and Research

Chronic liver disease in COVID-19 patients

Scientists explore kinetics of naturally induced anti-SARS-CoV-2 antibodies in the Kenyan population

Silver nanoparticle and polyurethane composite provides potential coating options to limit fomite transmission of SARS-CoV-2

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

Study evaluates efficacy of a candidate SARS-CoV-2 subunit vaccine to protect endangered black-footed-ferrets

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Study using human and animal-derived cell lines suggests human origin of SARS-CoV-2 Omicron variant

Study suggests an immunological benefit of combining previous natural infection with vaccination against COVID-19 using a combination of different vaccine platforms

Researchers identify a new gene implicated in rare lysosomal storage disorder

The immune responses and safety of fractional third-doses of heterologous COVID-19 vaccines after CoronaVac primary series

Stanford researchers create new technique for controlling protein production

Researchers uncover an intriguing previously unknown ability of Swiss army knife enzyme

Study opens avenues to improve prognosis of children with congenital hypogonadotropic hypogonadism

Study shows the important role of hepatocyte adenosine kinase in NAFLD progression

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Novel protein vaccine NVX-CoV2373 triggered functional T cell responses to SARS-CoV-2

Structural analysis of monkeypox virus H1 dual phosphatase as a pan-poxvirus target

Study shows SARS-CoV-2 infects human adipose tissue and undergoes productive infection in fat cells

Omicron reduces host antibody response by lower B-cell antigenicity

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Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo